Blocking LINGO-1 function promotes retinal ganglion cell survival following ocular hypertension and optic nerve transection

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 3, 2008, Pages 975-985

  Fu, Qing Ling ^a,b   Hu, Bing ^a,b   Wu, Tian ^a,b   Pepinsky, R Blake ^c   Mi, Sha ^c   So, Kwok Fai ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; NEUROTROPHIN RECEPTOR P75; NOGO 66 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN INHIBITOR; PROTEIN KINASE B; PROTEIN LINGO 1; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; BLOCKING ANTIBODY; LINGO1 PROTEIN, RAT; MEMBRANE PROTEIN; NERVE PROTEIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; IMMUNOHISTOCHEMISTRY; INTRAOCULAR HYPERTENSION; NERVE TRANSECTION; NEUROPROTECTION; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; RETINA GANGLION CELL; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CYTOLOGY; DISEASE MODEL; DRUG ANTAGONISM; ENZYME IMMUNOASSAY; FLUORESCENT ANTIBODY TECHNIQUE; INTRAOCULAR PRESSURE; METABOLISM; MOUSE; OPTIC NERVE INJURY; PHYSIOLOGY; RETINA; SPRAGUE DAWLEY RAT; UPREGULATION; VITREOUS BODY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIBODIES, BLOCKING; BLOTTING, WESTERN; CELL SURVIVAL; DISEASE MODELS, ANIMAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOENZYME TECHNIQUES; INTRAOCULAR PRESSURE; MEMBRANE PROTEINS; MICE; NERVE TISSUE PROTEINS; OCULAR HYPERTENSION; OPTIC NERVE INJURIES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RETINA; RETINAL GANGLION CELLS; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; UP-REGULATION; VITREOUS BODY;

EID: 41949111140     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1199     Document Type: Article

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