Overexpression of Akt1 upregulates glycogen synthase activity and phosphorylation of mTOR in IRS-1 knockdown HepG2 cells

Journal of Cellular Biochemistry

Volumn 103, Issue 5, 2008, Pages 1424-1437

  Varma, Shailly ^a   Khandelwal, Ramji L ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Akt1 (Ser 473); Glycogen synthase; HepG2; IRS 1 knockdown; mTOR (Ser 2448); p70S6K (Thr 389)

Indexed keywords

GLYCOGEN SYNTHASE; INSULIN RECEPTOR SUBSTRATE 1; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL STIMULATION; CELL STRAIN HEPG2; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME PHOSPHORYLATION; GLYCOGEN METABOLISM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INSULIN RESISTANCE; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE, TUMOR; CELL PROLIFERATION; GLYCOGEN; GLYCOGEN SYNTHASE; HUMANS; INSULIN; PHOSPHORYLATION; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 41749111571     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21525     Document Type: Article

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