TGFβ1 deficiency does not affect the generation and maintenance of CD4+CD25+FOXP3+ putative Treg cells, but causes their numerical inadequacy and loss of regulatory function

Clinical Immunology

Volumn 127, Issue 2, 2008, Pages 206-213

  Bommireddy, Ramireddy ^a,b   Babcock, George F ^c,d   Singh, Ram R ^e   Doetschman, Thomas ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d SHRINERS HOSPITALS FOR CHILDREN   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Autoimmunity; DO11.10; FOXP3; Inflammation; Knockout mice; Treg cells; TGF 1; Tolerance

Indexed keywords

TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; CD69 ANTIGEN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; L SELECTIN; LEUKOCYTE ANTIGEN; T LYMPHOCYTE ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CD4+ CD25+ T LYMPHOCYTE; CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE; ANIMAL; BAGG ALBINO MOUSE; CELL PROLIFERATION; CYTOLOGY; FLOW CYTOMETRY; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; MOUSE MUTANT; PHENOTYPE; SPLEEN; THYMUS;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; AUTOIMMUNITY; CELL PROLIFERATION; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; IMMUNE TOLERANCE; L-SELECTIN; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICE, TRANSGENIC; PHENOTYPE; SPLEEN; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND; TRANSFORMING GROWTH FACTOR BETA1;

EID: 41549164685     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2007.12.008     Document Type: Article

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