Self-antigen recognition by TGFβ1-deficient T cells causes their activation and systemic inflammation

Laboratory Investigation

Volumn 86, Issue 10, 2006, Pages 1008-1019

  Bommireddy, Ramireddy ^a,f   Pathak, Leena J ^a   Martin, Jennifer ^a   Ormsby, Ilona ^a   Engle, Sandra J ^b   Boivin, Gregory P ^a   Babcock, George F ^a,c   Eriksson, Anna U ^d   Singh, Ram R ^d,e   Doetschman, Thomas ^a,f  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b PFIZER INC   (United States)

^c SHRINERS HOSPITALS FOR CHILDREN   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF ARIZONA   (United States)

Author keywords

Autoimmunity; Inflammation; Knockout; Self antigen; T cells; TGF 1

Indexed keywords

ANTIGEN; RAG1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CELL ACTIVATION; CELL MATURATION; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; EX VIVO STUDY; GENE EXPRESSION; IN VIVO STUDY; INFLAMMATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; THYMOCYTE; TRANSGENE;

ANIMALS; AUTOANTIGENS; AUTOIMMUNITY; INFLAMMATION; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; T-LYMPHOCYTES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 33748849303     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700460     Document Type: Article

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