메뉴 건너뛰기




Volumn 166, Issue 4, 2004, Pages 465-471

Dynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles

Author keywords

Dynactin; Kinesin; Microtubule; Mitosis; Spindle

Indexed keywords

BINDING PROTEIN; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; KINESIN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN KIF2A; PROTEIN KIN1; PROTEIN NUMA; UNCLASSIFIED DRUG;

EID: 4143127831     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200404015     Document Type: Article
Times cited : (165)

References (31)
  • 1
    • 0033005733 scopus 로고    scopus 로고
    • Accessory protein regulation of microtubule dynamics throughout the cell cycle
    • Cassimeris, L. 1999. Accessory protein regulation of microtubule dynamics throughout the cell cycle. Curr. Opin. Cell Biol. 11:134-141.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 134-141
    • Cassimeris, L.1
  • 2
    • 0032608492 scopus 로고    scopus 로고
    • The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro
    • Desai, A., A. Murray, T.J. Mitchison, and C.E. Walczak. 1999a. The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro. Methods Cell Biol. 61:385-412.
    • (1999) Methods Cell Biol. , vol.61 , pp. 385-412
    • Desai, A.1    Murray, A.2    Mitchison, T.J.3    Walczak, C.E.4
  • 3
    • 0033534575 scopus 로고    scopus 로고
    • Kin I kinesins are microtubule-destabilizing enzymes
    • Desai, A., S. Verma, T.J. Mitchison, and C.E. Walczak. 1999b. Kin I kinesins are microtubule-destabilizing enzymes. Cell. 96:69-78.
    • (1999) Cell , vol.96 , pp. 69-78
    • Desai, A.1    Verma, S.2    Mitchison, T.J.3    Walczak, C.E.4
  • 4
    • 0035205087 scopus 로고    scopus 로고
    • A mammalian partner of inscuteable binds NuMA and regulates mitotic spindle organization
    • Du, Q., P.T. Stukenberg, and I.G. Macara. 2001. A mammalian partner of inscuteable binds NuMA and regulates mitotic spindle organization. Nat. Cell Biol. 3:1069-1075.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 1069-1075
    • Du, Q.1    Stukenberg, P.T.2    Macara, I.G.3
  • 5
    • 0037137429 scopus 로고    scopus 로고
    • LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation
    • Du, Q., L. Taylor, D.A. Compton, and I.G. Macara. 2002. LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation. Curr. Biol. 12:1928-1933.
    • (2002) Curr. Biol. , vol.12 , pp. 1928-1933
    • Du, Q.1    Taylor, L.2    Compton, D.A.3    Macara, I.G.4
  • 6
    • 0029913484 scopus 로고    scopus 로고
    • Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis
    • Echeverri, C.J., B.M. Paschal, K.T. Vaughan, and R.B. Vallee. 1996. Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J. Cell Biol. 132:617-633.
    • (1996) J. Cell Biol. , vol.132 , pp. 617-633
    • Echeverri, C.J.1    Paschal, B.M.2    Vaughan, K.T.3    Vallee, R.B.4
  • 7
    • 0031372605 scopus 로고    scopus 로고
    • Mechanics of microtubule-based membrane extension
    • Fygenson, D.K., J.F. Marko, and A. Libchaber. 1997. Mechanics of microtubule-based membrane extension. Phys. Rev. Lett. 79:4497-4500.
    • (1997) Phys. Rev. Lett. , vol.79 , pp. 4497-4500
    • Fygenson, D.K.1    Marko, J.F.2    Libchaber, A.3
  • 8
    • 4143075910 scopus 로고    scopus 로고
    • The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK
    • Ganem, N., and D.A. Compton. 2004 The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK. J. Cell Biol. 166:473-478.
    • (2004) J. Cell Biol. , vol.166 , pp. 473-478
    • Ganem, N.1    Compton, D.A.2
  • 9
    • 0028877327 scopus 로고
    • NuMA is required for the organization of microtubules into aster-like mitotic arrays
    • Gaglio, T., A. Saredi, and D.A. Compton. 1995. NuMA is required for the organization of microtubules into aster-like mitotic arrays. J. Cell Biol. 131:693-708.
    • (1995) J. Cell Biol. , vol.131 , pp. 693-708
    • Gaglio, T.1    Saredi, A.2    Compton, D.A.3
  • 10
    • 0141768258 scopus 로고    scopus 로고
    • The roles of microtubule-based motor proteins in mitosis: Comprehensive RNAi analysis in the Drosophila S2 cell line
    • Goshima, G., and R.D. Vale. 2003. The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line. J. Cell Biol. 162:1003-1016.
    • (2003) J. Cell Biol. , vol.162 , pp. 1003-1016
    • Goshima, G.1    Vale, R.D.2
  • 11
    • 0029836330 scopus 로고    scopus 로고
    • Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts
    • Heald, R., R. Tournebize, T. Blank, R. Sandaltzopoulos, P. Becker, A. Hyman, and E. Karsenti. 1996. Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature. 382: 420-425.
    • (1996) Nature , vol.382 , pp. 420-425
    • Heald, R.1    Tournebize, R.2    Blank, T.3    Sandaltzopoulos, R.4    Becker, P.5    Hyman, A.6    Karsenti, E.7
  • 12
    • 0030751640 scopus 로고    scopus 로고
    • Spindle assembly in Xenopus egg extracts: Respective roles of centrosomes and microtubule self-organization
    • Heald, R., R. Tournebize, A. Habermann, E. Karsenti, and A. Hyman. 1997. Spindle assembly in Xenopus egg extracts: respective roles of centrosomes and microtubule self-organization. J. Cell Biol. 138:615-628.
    • (1997) J. Cell Biol. , vol.138 , pp. 615-628
    • Heald, R.1    Tournebize, R.2    Habermann, A.3    Karsenti, E.4    Hyman, A.5
  • 13
    • 0035945356 scopus 로고    scopus 로고
    • Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation
    • Howell, B.J., B.F. McEwen, J.C. Canman, D.B. Hoffman, E.M. Farrar, C.L. Rieder, and E.D. Salmon. 2001. Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation. J. Cell Biol. 155:1159-1172.
    • (2001) J. Cell Biol. , vol.155 , pp. 1159-1172
    • Howell, B.J.1    McEwen, B.F.2    Canman, J.C.3    Hoffman, D.B.4    Farrar, E.M.5    Rieder, C.L.6    Salmon, E.D.7
  • 15
    • 0033004145 scopus 로고    scopus 로고
    • Cytoplasmic dynein and dynactin in cell division and intracellular transport
    • Karki, S., and E.L. Holzbaur. 1999. Cytoplasmic dynein and dynactin in cell division and intracellular transport. Curr. Opin. Cell Biol. 11:45-53.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 45-53
    • Karki, S.1    Holzbaur, E.L.2
  • 17
    • 0028977966 scopus 로고
    • Minus-end-directed motion of kinesin-coated microspheres driven by microtubule depolymerization
    • Lombillo, V.A., R.J. Stewart, and J.R. McIntosh. 1995. Minus-end-directed motion of kinesin-coated microspheres driven by microtubule depolymerization. Nature. 373:161-164.
    • (1995) Nature , vol.373 , pp. 161-164
    • Lombillo, V.A.1    Stewart, R.J.2    McIntosh, J.R.3
  • 18
    • 0036792853 scopus 로고    scopus 로고
    • Poleward microtubule flux is a major component of spindle dynamics and anaphase a in mitotic Drosophila embryos
    • Maddox, P., A. Desai, K. Oegema, T.J. Mitchison, and E.D. Salmon. 2002. Poleward microtubule flux is a major component of spindle dynamics and anaphase a in mitotic Drosophila embryos. Curr. Biol. 12:1670-1674.
    • (2002) Curr. Biol. , vol.12 , pp. 1670-1674
    • Maddox, P.1    Desai, A.2    Oegema, K.3    Mitchison, T.J.4    Salmon, E.D.5
  • 19
    • 0030298137 scopus 로고    scopus 로고
    • A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly
    • Merdes, A., K. Ramyar, J.D. Vechio, and D.W. Cleveland. 1996. A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell. 87:447-458.
    • (1996) Cell , vol.87 , pp. 447-458
    • Merdes, A.1    Ramyar, K.2    Vechio, J.D.3    Cleveland, D.W.4
  • 20
    • 0034658078 scopus 로고    scopus 로고
    • Formation of spindle poles by dynein/dynactin-dependent transport of NuMA
    • Merdes, A., R. Heald, K. Samejima, W.C. Earnshaw, and D.W. Cleveland. 2000. Formation of spindle poles by dynein/dynactin-dependent transport of NuMA. J. Cell Biol. 149:851-862.
    • (2000) J. Cell Biol. , vol.149 , pp. 851-862
    • Merdes, A.1    Heald, R.2    Samejima, K.3    Earnshaw, W.C.4    Cleveland, D.W.5
  • 21
    • 0024369644 scopus 로고
    • Polewards microtubule flux in the mitotic spindle: Evidence from photoactivation of fluorescence
    • Mitchison, T.J. 1989. Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence. J. Cell Biol. 109:637-652.
    • (1989) J. Cell Biol. , vol.109 , pp. 637-652
    • Mitchison, T.J.1
  • 22
    • 0028948491 scopus 로고
    • KIF2 is a new microtubule-based anterograde motor that transports membranous organelles distinct from those carried by kinesin heavy chain or KIF3A/B
    • Noda, Y., R. Sato-Yoshitake, S. Kondo, M. Nangaku, and N. Hirokawa. 1995. KIF2 is a new microtubule-based anterograde motor that transports membranous organelles distinct from those carried by kinesin heavy chain or KIF3A/B. J. Cell Biol. 129:157-167.
    • (1995) J. Cell Biol. , vol.129 , pp. 157-167
    • Noda, Y.1    Sato-Yoshitake, R.2    Kondo, S.3    Nangaku, M.4    Hirokawa, N.5
  • 25
    • 0030031999 scopus 로고    scopus 로고
    • XKCM1: A Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly
    • Walczak, C.E., T.J. Mitchison, and A. Desai. 1996. XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly. Cell. 84:37-47.
    • (1996) Cell , vol.84 , pp. 37-47
    • Walczak, C.E.1    Mitchison, T.J.2    Desai, A.3
  • 26
    • 0037195285 scopus 로고    scopus 로고
    • The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly
    • Walczak, C.E., E.G. Gan, A. Desai, T.J. Mitchison, and S.L. Kline-Smith. 2002. The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly. Curr. Biol. 12:1885-1889.
    • (2002) Curr. Biol. , vol.12 , pp. 1885-1889
    • Walczak, C.E.1    Gan, E.G.2    Desai, A.3    Mitchison, T.J.4    Kline-Smith, S.L.5
  • 27
    • 0032488046 scopus 로고    scopus 로고
    • Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells
    • Waterman-Storer, C.M., A. Desai, J.C. Bulinski, and E.D. Salmon. 1998. Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells. Curr. Biol. 8:1227-1230.
    • (1998) Curr. Biol. , vol.8 , pp. 1227-1230
    • Waterman-Storer, C.M.1    Desai, A.2    Bulinski, J.C.3    Salmon, E.D.4
  • 28
    • 0029836707 scopus 로고    scopus 로고
    • The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work
    • Waters, J.C., T.J. Mitchison, C.L. Rieder, and E.D. Salmon. 1996. The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work. Mol. Biol. Cell. 7:1547-1558.
    • (1996) Mol. Biol. Cell , vol.7 , pp. 1547-1558
    • Waters, J.C.1    Mitchison, T.J.2    Rieder, C.L.3    Salmon, E.D.4
  • 29
    • 0032622374 scopus 로고    scopus 로고
    • Recombinant p50/dynamitin as a tool to examine the role of dynactin in intracellular processes
    • Wittmann, T., and T. Hyman. 1999. Recombinant p50/dynamitin as a tool to examine the role of dynactin in intracellular processes. Methods Cell Biol. 61: 137-143.
    • (1999) Methods Cell Biol. , vol.61 , pp. 137-143
    • Wittmann, T.1    Hyman, T.2
  • 30
    • 0035146128 scopus 로고    scopus 로고
    • The spindle: A dynamic assembly of microtubules and motors
    • Wittmann, T., A. Hyman, and A. Desai. 2001. The spindle: a dynamic assembly of microtubules and motors. Nat. Cell Biol. 3:E28-E34.
    • (2001) Nat. Cell Biol. , vol.3
    • Wittmann, T.1    Hyman, A.2    Desai, A.3
  • 31
    • 0034681261 scopus 로고    scopus 로고
    • Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization
    • Yu, F., X. Morin, Y. Cai, X. Yang, and W. Chia. 2000. Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization. Cell. 100:399-409.
    • (2000) Cell , vol.100 , pp. 399-409
    • Yu, F.1    Morin, X.2    Cai, Y.3    Yang, X.4    Chia, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.