Reperfusion activates metalloproteinases that contribute to neurovascular injury

Experimental Neurology

Volumn 210, Issue 2, 2008, Pages 549-559

  Lu, Aigang ^a,b   Clark, Joseph F ^a,b   Broderick, Joseph P ^a,b   Pyne Geithman, Gail J ^a,b   Wagner, Kenneth R ^a,b   Ran, Ruiqiong ^c   Khatri, Pooja ^a,b   Tomsick, Thomas ^a,b   Sharp, Frank R ^c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain damage; Cerebral ischemia; Neuroprotection; Rats

Indexed keywords

4 AMINOBENZOYL GLYCYLPROLYL DEXTRO LEUCYL DEXTRO ALANYL HYDROXAMATE; ANTIGEN; COLLAGEN TYPE 4; CRESYL VIOLET; DYE; ENDOTHELIAL BARRIER ANTIGEN; GELATINASE A; GELATINASE B; HYDROXAMIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BLOOD VESSEL INJURY; BRAIN INJURY; CONTROLLED STUDY; CORPUS STRIATUM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; GLIA CELL; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY; NERVE CELL LESION; NEUROVASCULAR INJURY; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; ZYMOGRAPHY;

ANALYSIS OF VARIANCE; ANIMALS; AUTOANTIGENS; BASEMENT MEMBRANE; CEREBROVASCULAR TRAUMA; COLLAGEN TYPE IV; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; ENZYME ACTIVATION; ENZYME INHIBITORS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION; REPERFUSION INJURY; TIME FACTORS;

EID: 41149138828     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2007.12.003     Document Type: Article

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