Neuronal activity-dependent increase of net matrix metalloproteinase activity is associated with MMP-9 neurotoxicity after kainate

European Journal of Neuroscience

Volumn 18, Issue 6, 2003, Pages 1507-1517

  Jourquin, Jérôme ^a   Tremblay, Evelyne ^a   Décanis, Nadège ^a   Charton, Gérard ^a   Hanessian, Stephen ^b   Chollet, Anne Marie ^c   Le Diguardher, Thierry ^c   Khrestchatisky, Michel ^a   Rivera, Santiago ^a  

^a CNRS   (France)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Excitotoxicity; Hippocampus; Inflammation; Neuronal death; Organotypic culture; Rat; TIMP

Indexed keywords

BATIMASTAT; GELATINASE A; GELATINASE B; GELATINASE INHIBITOR; HYDROXAMIC ACID; KAINIC ACID; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; S 24994; S 34237; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL; CONTROLLED STUDY; ENCEPHALITIS; ENZYME ACTIVITY; GLIA CELL; HIPPOCAMPUS; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PYRAMIDAL NERVE CELL; RAT; SEIZURE; TISSUE CULTURE; ZYMOGRAPHY;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD147; ANTIGENS, NEOPLASM; ANTIGENS, SURFACE; AVIAN PROTEINS; BLOOD PROTEINS; BLOOD VESSELS; CELL COUNT; CELL DEATH; DIAZEPAM; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENCEPHALITIS; EXCITATORY AMINO ACID AGONISTS; GABA MODULATORS; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; KAINIC ACID; MALE; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; MEMBRANE GLYCOPROTEINS; NEUROGLIA; NEURONS; ORGAN CULTURE TECHNIQUES; PHENANTHROLINES; PHENYLMERCURY COMPOUNDS; PROTEASE INHIBITORS; RATS; RATS, WISTAR; SEIZURES; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 0141816709     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02876.x     Document Type: Article

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