Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice

Journal of Neurochemistry

Volumn 105, Issue 1, 2008, Pages 262-271

  Lopez, José R ^a,b   Lyckman, Alvin ^c   Oddo, Salvatore ^d   LaFerla, Frank M ^d   Querfurth, Henry W ^c   Shtifman, Alexander ^c,e  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e ST ELIZABETH'S MEDICAL CENTER   (United States)

Author keywords

amyloid; Alzheimer's disease; Ca2+ entry; Inositol trisphosphate receptors; L type channels; Ryanodine receptors

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 2,6 DICHLORO 4 DIMETHYLAMINOAMPHETAMINE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CALCIUM; CALCIUM CHANNEL; INOSITOL TRISPHOSPHATE; NIFEDIPINE; RYANODINE; RYANODINE RECEPTOR; SFK 96365; UNCLASSIFIED DRUG; XESTOSPONGIN C;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CELL; CALCIUM HOMEOSTASIS; CELL CULTURE; CONTROLLED STUDY; DRUG INHIBITION; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE STEADY POTENTIAL; MICROELECTRODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FOLDING;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HOMEOSTASIS; HUMANS; MICE; MICE, TRANSGENIC; NEOCORTEX; NEURONS; PRESENILIN-1; RYANODINE; TAU PROTEINS;

MUS;

EID: 41149133293     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.05135.x     Document Type: Article

References (59)

1. Alvarez-Leefmans F. J., Rink T. J. Tsien R. Y. (1981) Free calcium ions in neurones of Helix aspersa measured with ion-selective micro-electrodes. J. Physiol. 315, 531 548.
2. Billings L. M., Oddo S., Green K. N., McGaugh J. L. LaFerla F. M. (2005) Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron 45, 675 688.
3. Borchelt D. R., Thinakaran G., Eckman C. B. et al. (1996) Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron 17, 1005 1013.
4. Borchelt D. R., Ratovitski T., van Lare J., Lee M. K., Gonzales V., Jenkins N. A., Copeland N. G., Price D. L. Sisodia S. S. (1997) Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19, 939 945.
5. Brewer G. J. (1997) Isolation and culture of adult rat hippocampal neurons. J. Neurosci. Methods 71, 143 155.
6. Campbell L. W., Hao S. Y., Thibault O., Blalock E. M. Landfield P. W. (1996) Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons. J. Neurosci. 16, 6286 6295.
7. Chan S. L., Mayne M., Holden C. P., Geiger J. D. Mattson M. P. (2000) Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons. J. Biol. Chem. 275, 18195 18200.
8. 2+ entry by depolarization of skeletal myotubes. Proc. Natl Acad. Sci. USA 101, 15793 15798.
9. Choe C. U. Ehrlich B. E. (2006) The inositol 1,4,5-trisphosphate receptor (IP3R) and its regulators: sometimes good and sometimes bad teamwork. Sci. STKE 2006, re15.
10. Christensen R. A., Shtifman A., Allen P. D., Lopez J. R. Querfurth H. W. (2004) Calcium dyshomeostasis in beta-amyloid and tau-bearing skeletal myotubes. J. Biol. Chem. 279, 53524 53532.
11. Davare M. A. Hell J. W. (2003) Increased phosphorylation of the neuronal L-type Ca(2+) channel Ca(v)1.2 during aging. Proc. Natl Acad. Sci. USA 100, 16018 16023.
12. Fill M. Copello J. A. (2002) Ryanodine receptor calcium release channels. Physiol. Rev. 82, 893 922.
13. Freir D. B., Costello D. A. Herron C. E. (2003) A beta 25-35-induced depression of long-term potentiation in area CA1 in vivo and in vitro is attenuated by verapamil. J. Neurophysiol. 89, 3061 3069.
14. Fu H., Li W., Lao Y. et al. (2006) Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels. J. Neurochem. 98, 1400 1410.
15. Gafni J., Munsch J. A., Lam T. H., Catlin M. C., Costa L. G., Molinski T. F. Pessah I. N. (1997) Xestospongin: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor. Neuron 19, 723 733.
16. 2+ entry is associated with the familial Alzheimer's disease presenilin-2 T122R mutation and anticipates the onset of dementia. Neurobiol. Dis. 18, 638 648.
17. Gouras G. K., Almeida C. G. Takahashi R. H. (2005) Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease. Neurobiol. Aging 26, 1235 1244.
18. 2+ entry and immediate early gene expression in mouse hepatoma cells. Toxicology 220, 218 231.
19. Harkany T., Abraham I., Timmerman W. et al. (2000) beta-amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis. Eur. J. Neurosci. 12, 2735 2745.
20. Herms J., Schneider I., Dewachter I., Caluwaerts N., Kretzschmar H. Van Leuven F. (2003) Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein. J. Biol. Chem. 278, 2484 2489.
21. Kelliher M., Fastbom J., Cowburn R. F., Bonkale W., Ohm T. G., Ravid R., Sorrentino V. O'Neill C. (1999) Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and beta-amyloid pathologies. Neuroscience 92, 499 513.
22. Kirischuk S. Verkhratsky A. (1996) Calcium homeostasis in aged neurones. Life Sci. 59, 451 459.
23. Kirischuk S., Pronchuk N. Verkhratsky A. (1992) Measurements of intracellular calcium in sensory neurons of adult and old rats. Neuroscience 50, 947 951.
24. Kirischuk S., Voitenko N., Kostyuk P. Verkhratsky A. (1996) Age-associated changes of cytoplasmic calcium homeostasis in cerebellar granule neurons in situ: investigation on thin cerebellar slices. Exp. Gerontol. 31, 475 487.
25. LaFerla F. M. (2002) Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat. Rev. Neurosci. 3, 862 872.
26. Leissring M. A., Parker I. LaFerla F. M. (1999a) Presenilin-2 mutations modulate amplitude and kinetics of inositol 1, 4,5-trisphosphate-mediated calcium signals. J. Biol. Chem. 274, 32535 32538.
27. Leissring M. A., Paul B. A., Parker I., Cotman C. W. LaFerla F. M. (1999b) Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes. J. Neurochem. 72, 1061 1068.
28. Leissring M. A., Akbari Y., Fanger C. M., Cahalan M. D., Mattson M. P. LaFerla F. M. (2000) Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice. J. Cell Biol. 149, 793 798.
29. Mack W. M., Zimanyi I. Pessah I. N. (1992) Discrimination of multiple binding sites for antagonists of the calcium release channel complex of skeletal and cardiac sarcoplasmic reticulum. J. Pharmacol. Exp. Ther. 262, 1028 1037.
30. MacManus A., Ramsden M., Murray M., Henderson Z., Pearson H. A. Campbell V. A. (2000) Enhancement of (45)Ca(2+) influx and voltage-dependent Ca(2+) channel activity by beta-amyloid-(1-40) in rat cortical synaptosomes and cultured cortical neurons. Modulation by the proinflammatory cytokine interleukin-1beta. J. Biol. Chem. 275, 4713 4718.
31. 2+ concentration of hippocampal CA1 pyramidal neurons. J. Neurophysiol. 76, 3460 3470.
32. Mattson M. P., LaFerla F. M., Chan S. L., Leissring M. A., Shepel P. N. Geiger J. D. (2000) Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders. Trends Neurosci. 23, 222 229.
33. Miyamoto S., Izumi M., Hori M., Kobayashi M., Ozaki H. Karaki H. (2000) Xestospongin C, a selective and membrane-permeable inhibitor of IP(3) receptor, attenuates the positive ionotropic effect of alpha-adrenergic stimulation in guinea-pig papillary muscle. Br. J. Pharmacol. 130, 650 654.
34. 2+ leak function of presenilin 1. J. Clin. Invest. 117, 1230 1239.
35. Oddo S., Caccamo A., Kitazawa M., Tseng B. P. LaFerla F. M. (2003a) Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiol. Aging 24, 1063 1070.
36. Oddo S., Caccamo A., Shepherd J. D., Murphy M. P., Golde T. E., Kayed R., Metherate R., Mattson M. P., Akbari Y. LaFerla F. M. (2003b) Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39, 409 421.
37. Parks J. K., Smith T. S., Trimmer P. A., Bennett J. P. Jr. Parker W. D. Jr. (2001) Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro. J. Neurochem. 76, 1050 1056.
38. Pierrot N., Ghisdal P., Caumont A. S. Octave J. N. (2004) Intraneuronal amyloid-beta1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death. J. Neurochem. 88, 1140 1150.
39. Raza M., Deshpande L. S., Blair R. E., Carter D. S., Sombati S. DeLorenzo R. J. (2007) Aging is associated with elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons. Neurosci. Lett. 418, 77 81.
40. 2+ channels. FASEB J. 19, 150 152.
41. Selkoe D. J. (2001) Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81, 741 766.
42. Smith I. F., Boyle J. P., Vaughan P. F., Pearson H. A., Cowburn R. F. Peers C. S. (2002) Ca(2+) stores and capacitative Ca(2+) entry in human neuroblastoma (SH-SY5Y) cells expressing a familial Alzheimer's disease presenilin-1 mutation. Brain Res. 949, 105 111.
43. 2+ release in the 3xTg-AD mouse model of Alzheimer's disease. J. Neurochem. 94, 1711 1718.
44. 2+ signals and altered membrane excitability. J. Neurosci. 24, 508 513.
45. 2+ disruptions in young, adult, and aged Alzheimer's disease mice. J. Neurosci. 26, 5180 5189.
46. Thibault O. Landfield P. W. (1996) Increase in single L-type calcium channels in hippocampal neurons during aging. Science 272, 1017 1020.
47. +]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. J. Neurosci. 21, 9744 9756.
48. 2+-selective electrodes: a novel PVC-gelled neutral carrier mixture compared with other currently available sensors. J. Neurosci. Methods 4, 73 86.
49. 2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations. Cell 126, 981 993.
50. 2+ channels: a possible involvement of free radicals. J. Neurochem. 68, 265 271.
51. Verkhratsky A. (2005) Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons. Physiol. Rev. 85, 201 279.
52. Viel J. J., McManus D. Q., Cady C., Evans M. S. Brewer G. J. (2001) Temperature and time interval for culture of postmortem neurons from adult rat cortex. J. Neurosci. Res. 64, 311 321.
53. 2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture. J. Neurochem. 62, 372 375.
54. Xie C. W. (2004) Calcium-regulated signaling pathways: role in amyloid beta-induced synaptic dysfunction. Neuromol. Med. 6, 53 64.
55. 2+ homeostasis in aged cerebellar granule neurons in brain slices. J. Neurosci. 22, 10761 10771.
56. i in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the sarcoplasmic reticulum. Am. J. Physiol. Cell Physiol. 292, 1591 1598.
57. Ye C., Walsh D. M., Selkoe D. J. Hartley D. M. (2004) Amyloid beta-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation. Neurosci. Lett. 366, 320 325.
58. Yoo A. S., Cheng I., Chung S. et al. (2000) Presenilin-mediated modulation of capacitative calcium entry. Neuron 27, 561 572.
59. 2+ release from intracellular stores. Neurobiol. Dis. 15, 269 278.