The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine

Molecular Pharmacology

Volumn 73, Issue 3, 2008, Pages 824-832

  Zhang, Yong Wei ^a   Zhang, Zhi Xiang ^a   Miao, Ze Hong ^a   Ding, Jian ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; CHECKPOINT KINASE RAD3; DITERPENOID; DOUBLE STRANDED DNA; PROTEASOME; SALVICINE; SMALL INTERFERING RNA; TELOMERIC REPEAT BINDING FACTOR 2; UNCLASSIFIED DRUG;

ARTICLE; CANCER GROWTH; CELL DEGENERATION; CELL DISRUPTION; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; DRUG SYNTHESIS; ENZYME ACTIVATION; GENE; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TELOMERE; TRANSCRIPTION INITIATION; TRF2 GENE;

CARCINOMA; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; COMET ASSAY; DNA BREAKS, DOUBLE-STRANDED; DNA-BINDING PROTEINS; HUMANS; LUNG NEOPLASMS; NAPHTHOQUINONES; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; STATISTICS AS TOPIC; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 2; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

EID: 40849102709     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.039081     Document Type: Article

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