-
1
-
-
8444223507
-
Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus
-
Anolik JH, Barnard J, Cappione A, et al (2004). Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus. Arthritis Rheum 50:3580 3590.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3580-3590
-
-
Anolik, J.H.1
Barnard, J.2
Cappione, A.3
Al, E.4
-
2
-
-
0027572233
-
Sjogren's syndrome: Oral and dental considerations
-
78 82, 84 86
-
Atkinson JC, Fox PC (1993). Sjogren's syndrome: oral and dental considerations. J Am Dent Assoc 124:74 76, 78 82, 84 86.
-
(1993)
J Am Dent Assoc
, vol.124
, pp. 74-76
-
-
Atkinson, J.C.1
Fox, P.C.2
-
3
-
-
0036272696
-
Suppression of tumor necrosis factor alpha-induced matrix metalloproteinase 9 production in human salivary gland acinar cells by cepharanthine occurs via down-regulation of nuclear factor kappaB: A possible therapeutic agent for preventing the destruction of the acinar structure in the salivary glands of Sjogren's syndrome patients
-
Azuma M, Aota K, Tamatani T, et al (2002). Suppression of tumor necrosis factor alpha-induced matrix metalloproteinase 9 production in human salivary gland acinar cells by cepharanthine occurs via down-regulation of nuclear factor kappaB: a possible therapeutic agent for preventing the destruction of the acinar structure in the salivary glands of Sjogren's syndrome patients. Arthritis Rheum 46:1585 1594.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1585-1594
-
-
Azuma, M.1
Aota, K.2
Tamatani, T.3
Al, E.4
-
4
-
-
0032543858
-
Disease activity and risk of lymphoma in patients with rheumatoid arthritis: Nested case-control study
-
Baecklund E, Ekbom A, Sparen P, et al (1998). Disease activity and risk of lymphoma in patients with rheumatoid arthritis: nested case-control study. BMJ 317:180 181.
-
(1998)
BMJ
, vol.317
, pp. 180-181
-
-
Baecklund, E.1
Ekbom, A.2
Sparen, P.3
Al, E.4
-
5
-
-
0027211704
-
Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: Implications for TNF receptor activation
-
Banner DW, D'Arcy A, Janes W, et al (1993). Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. Cell 73:431 445.
-
(1993)
Cell
, vol.73
, pp. 431-445
-
-
Banner, D.W.1
D'Arcy, A.2
Janes, W.3
Al, E.4
-
6
-
-
0034735827
-
A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis
-
Bathon JM, Martin RW, Fleischmann RM, et al (2000). A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis. N Engl J Med 343:1586 1593.
-
(2000)
N Engl J Med
, vol.343
, pp. 1586-1593
-
-
Bathon, J.M.1
Martin, R.W.2
Fleischmann, R.M.3
Al, E.4
-
7
-
-
17244372491
-
Activation of the type I interferon system in primary Sjogren's syndrome: A possible etiopathogenic mechanism
-
Bave U, Nordmark G, Lovgren T, et al (2005). Activation of the type I interferon system in primary Sjogren's syndrome: a possible etiopathogenic mechanism. Arthritis Rheum 52:1185 1195.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1185-1195
-
-
Bave, U.1
Nordmark, G.2
Lovgren, T.3
Al, E.4
-
8
-
-
0022648104
-
Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors
-
Bertolini DR, Nedwin GE, Bringman TS, et al (1986). Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors. Nature 319:516 518.
-
(1986)
Nature
, vol.319
, pp. 516-518
-
-
Bertolini, D.R.1
Nedwin, G.E.2
Bringman, T.S.3
Al, E.4
-
9
-
-
33644967813
-
CTLA4Ig: Bridging the basic immunology with clinical application
-
Bluestone JA, St Clair EW, Turka LA, et al (2006). CTLA4Ig: bridging the basic immunology with clinical application. Immunity 24:233 238.
-
(2006)
Immunity
, vol.24
, pp. 233-238
-
-
Bluestone, J.A.1
St Clair, E.W.2
Turka, L.A.3
Al, E.4
-
10
-
-
33646696885
-
Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
-
Bongartz T, Sutton AJ, Sweeting MJ, et al (2006). Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA 295:2275 2285.
-
(2006)
JAMA
, vol.295
, pp. 2275-2285
-
-
Bongartz, T.1
Sutton, A.J.2
Sweeting, M.J.3
Al, E.4
-
11
-
-
8644284823
-
The significance of salivary and serum interleukin 6 and basic fibroblast growth factor levels in patients with Sjogren's syndrome
-
Boras VV, Cikes N, Lukac J, et al (2004). The significance of salivary and serum interleukin 6 and basic fibroblast growth factor levels in patients with Sjogren's syndrome. Coll Antropol 28 (Suppl. 2 305 309.
-
(2004)
Coll Antropol
, vol.28
, Issue.2
, pp. 305-309
-
-
Boras, V.V.1
Cikes, N.2
Lukac, J.3
Al, E.4
-
12
-
-
33845357261
-
Syndromes and complications of interferon therapy
-
Borg FA, Isenberg DA (2007). Syndromes and complications of interferon therapy. Curr Opin Rheumatol 19:61 66.
-
(2007)
Curr Opin Rheumatol
, vol.19
, pp. 61-66
-
-
Borg, F.A.1
Isenberg, D.A.2
-
13
-
-
0014941813
-
A theory of self-nonself discrimination
-
Bretscher P, Cohn M (1970). A theory of self-nonself discrimination. Science 169:1042 1049.
-
(1970)
Science
, vol.169
, pp. 1042-1049
-
-
Bretscher, P.1
Cohn, M.2
-
14
-
-
0030024476
-
T cell clones from a Sjogren's syndrome salivary gland biopsy produce high levels of IL-10
-
Brookes SM, Cohen SB, Price EJ, et al (1996). T cell clones from a Sjogren's syndrome salivary gland biopsy produce high levels of IL-10. Clin Exp Immunol 103:268 272.
-
(1996)
Clin Exp Immunol
, vol.103
, pp. 268-272
-
-
Brookes, S.M.1
Cohen, S.B.2
Price, E.J.3
Al, E.4
-
15
-
-
34247564550
-
Immunology: Pimp my antibody
-
Check E (2007). Immunology: pimp my antibody. Nature 446:964 966.
-
(2007)
Nature
, vol.446
, pp. 964-966
-
-
Check, E.1
-
16
-
-
0035932519
-
Cytokine pathways and joint inflammation in rheumatoid arthritis
-
Choy EH, Panayi GS (2001). Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 344:907 916.
-
(2001)
N Engl J Med
, vol.344
, pp. 907-916
-
-
Choy, E.H.1
Panayi, G.S.2
-
17
-
-
0036190776
-
Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: Results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial
-
Cohen S, Hurd E, Cush J, et al (2002). Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum 46:614 624.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 614-624
-
-
Cohen, S.1
Hurd, E.2
Cush, J.3
Al, E.4
-
18
-
-
33746961890
-
Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks
-
Cohen SB, Emery P, Greenwald MW, et al (2006). Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Arthritis Rheum 54:2793 2806.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2793-2806
-
-
Cohen, S.B.1
Emery, P.2
Greenwald, M.W.3
Al, E.4
-
19
-
-
0042736054
-
Treatment of primary Sjogren's syndrome with low-dose human interferon alfa administered by the oromucosal route: Combined phase III results
-
Cummins MJ, Papas A, Kammer GM, et al (2003). Treatment of primary Sjogren's syndrome with low-dose human interferon alfa administered by the oromucosal route: combined phase III results. Arthritis Rheum 49:585 593.
-
(2003)
Arthritis Rheum
, vol.49
, pp. 585-593
-
-
Cummins, M.J.1
Papas, A.2
Kammer, G.M.3
Al, E.4
-
20
-
-
15944368279
-
Block and tackle: CTLA4Ig takes on lupus
-
Davidson A, Diamond B, Wofsy D, et al (2005). Block and tackle: CTLA4Ig takes on lupus. Lupus 14:197 203.
-
(2005)
Lupus
, vol.14
, pp. 197-203
-
-
Davidson, A.1
Diamond, B.2
Wofsy, D.3
Al, E.4
-
21
-
-
0028345082
-
Serum soluble interleukin 6 (IL-6) receptor and IL-6/soluble IL-6 receptor complex in systemic juvenile rheumatoid arthritis
-
De Benedetti F, Massa M, Pignatti P, et al (1994). Serum soluble interleukin 6 (IL-6) receptor and IL-6/soluble IL-6 receptor complex in systemic juvenile rheumatoid arthritis. J Clin Invest 93:2114 2119.
-
(1994)
J Clin Invest
, vol.93
, pp. 2114-2119
-
-
De Benedetti, F.1
Massa, M.2
Pignatti, P.3
Al, E.4
-
22
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello CA (1996). Biologic basis for interleukin-1 in disease. Blood 87:2095 2147.
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
23
-
-
53749095799
-
Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus
-
Dorner T, Kaufmann J, Wegener WA, et al (2006). Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus. Arthritis Res Ther 8:R74.
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Dorner, T.1
Kaufmann, J.2
Wegener, W.A.3
Al, E.4
-
24
-
-
33746945480
-
Influence of CTLA4 haplotypes on susceptibility and some extraglandular manifestations in primary Sjogren's syndrome
-
Downie-Doyle S, Bayat N, Rischmueller M, et al (2006). Influence of CTLA4 haplotypes on susceptibility and some extraglandular manifestations in primary Sjogren's syndrome. Arthritis Rheum 54:2434 2440.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2434-2440
-
-
Downie-Doyle, S.1
Bayat, N.2
Rischmueller, M.3
Al, E.4
-
25
-
-
2942537697
-
Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis
-
Edwards JC, Szczepanski L, Szechinski J, et al (2004). Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. N Engl J Med 350:2572 2581.
-
(2004)
N Engl J Med
, vol.350
, pp. 2572-2581
-
-
Edwards, J.C.1
Szczepanski, L.2
Szechinski, J.3
Al, E.4
-
26
-
-
0027438710
-
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha
-
Elliott MJ, Feldmann M, Maini RN, et al (1993). Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis Rheum 36:1681 1690.
-
(1993)
Arthritis Rheum
, vol.36
, pp. 1681-1690
-
-
Elliott, M.J.1
Feldmann, M.2
Maini, R.N.3
Al, E.4
-
27
-
-
0028143211
-
Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
-
Elliott MJ, Maini RN, Feldmann M, et al (1994). Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 344:1105 1110.
-
(1994)
Lancet
, vol.344
, pp. 1105-1110
-
-
Elliott, M.J.1
Maini, R.N.2
Feldmann, M.3
Al, E.4
-
28
-
-
0028953686
-
TNF alpha blockade in rheumatoid arthritis: Rationale, clinical outcomes and mechanisms of action
-
Elliott MJ, Maini RN, Feldmann M, et al (1995). TNF alpha blockade in rheumatoid arthritis: rationale, clinical outcomes and mechanisms of action. Int J Immunopharmacol 17:141 145.
-
(1995)
Int J Immunopharmacol
, vol.17
, pp. 141-145
-
-
Elliott, M.J.1
Maini, R.N.2
Feldmann, M.3
Al, E.4
-
29
-
-
33646483031
-
The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: Results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial
-
Emery P, Fleischmann R, Filipowicz-Sosnowska A, et al (2006). The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial. Arthritis Rheum 54:1390 1400.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1390-1400
-
-
Emery, P.1
Fleischmann, R.2
Filipowicz-Sosnowska, A.3
Al, E.4
-
30
-
-
0030017916
-
Interferon alpha-2 (IFN alpha 2) increases lacrimal and salivary function in Sjogren's syndrome patients. Preliminary results of an open pilot trial versus OH-chloroquine
-
Ferraccioli GF, Salaffi F, De Vita S, et al (1996). Interferon alpha-2 (IFN alpha 2) increases lacrimal and salivary function in Sjogren's syndrome patients. Preliminary results of an open pilot trial versus OH-chloroquine. Clin Exp Rheumatol 14:367 371.
-
(1996)
Clin Exp Rheumatol
, vol.14
, pp. 367-371
-
-
Ferraccioli, G.F.1
Salaffi, F.2
De Vita, S.3
Al, E.4
-
31
-
-
0036400157
-
Safety of anakinra, a recombinant interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis and comparison to anti-TNF-alpha agents
-
Fleishmann RM (2002). Safety of anakinra, a recombinant interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis and comparison to anti-TNF-alpha agents. Clin Exp Rheumatol 20 (5 Suppl. 27 S35 S41.
-
(2002)
Clin Exp Rheumatol
, vol.20
, Issue.527
-
-
Fleishmann, R.M.1
-
32
-
-
0348109372
-
Adalimumab, a fully human anti tumor necrosis factor-alpha monoclonal antibody, and concomitant standard antirheumatic therapy for the treatment of rheumatoid arthritis: Results of STAR (Safety Trial of Adalimumab in Rheumatoid Arthritis)
-
Furst DE, Schiff MH, Fleischmann RM, et al (2003). Adalimumab, a fully human anti tumor necrosis factor-alpha monoclonal antibody, and concomitant standard antirheumatic therapy for the treatment of rheumatoid arthritis: results of STAR (Safety Trial of Adalimumab in Rheumatoid Arthritis). J Rheumatol 30:2563 2571.
-
(2003)
J Rheumatol
, vol.30
, pp. 2563-2571
-
-
Furst, D.E.1
Schiff, M.H.2
Fleischmann, R.M.3
Al, E.4
-
33
-
-
35649016260
-
Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2007
-
Furst DE, Breedveld FC, Kalden JR, et al (2007). Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2007. Ann Rheum Dis 66 (Suppl. 3 iii2 iii22.
-
(2007)
Ann Rheum Dis
, vol.66
, Issue.3
-
-
Furst, D.E.1
Breedveld, F.C.2
Kalden, J.R.3
Al, E.4
-
34
-
-
40749130097
-
Abatacept inhibits structural damage progression in rheumatoid arthritis: Results from the long-term extension of the AIM trial
-
in press.
-
Genant HK, Peterfy CG, Westhovens R, et al (2007). Abatacept inhibits structural damage progression in rheumatoid arthritis: results from the long-term extension of the AIM trial. Ann Rheum Dis in press.
-
(2007)
Ann Rheum Dis
-
-
Genant, H.K.1
Peterfy, C.G.2
Westhovens, R.3
Al, E.4
-
35
-
-
0036274944
-
Etanercept versus methotrexate in patients with early rheumatoid arthritis: Two-year radiographic and clinical outcomes
-
Genovese MC, Bathon JM, Martin RW, et al (2002). Etanercept versus methotrexate in patients with early rheumatoid arthritis: two-year radiographic and clinical outcomes. Arthritis Rheum 46:1443 1450.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1443-1450
-
-
Genovese, M.C.1
Bathon, J.M.2
Martin, R.W.3
Al, E.4
-
36
-
-
2342551979
-
Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate
-
Genovese MC, Cohen S, Moreland L, et al (2004). Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate. Arthritis Rheum 50:1412 1419.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1412-1419
-
-
Genovese, M.C.1
Cohen, S.2
Moreland, L.3
Al, E.4
-
37
-
-
24944498854
-
Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition
-
Genovese MC, Becker JC, Schiff M, et al (2005). Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition. N Engl J Med 353:1114 1123.
-
(2005)
N Engl J Med
, vol.353
, pp. 1114-1123
-
-
Genovese, M.C.1
Becker, J.C.2
Schiff, M.3
Al, E.4
-
38
-
-
33746876396
-
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition
-
Goldbach-Mansky R, Dailey NJ, Canna SW, et al (2006). Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition. N Engl J Med 355:581 592.
-
(2006)
N Engl J Med
, vol.355
, pp. 581-592
-
-
Goldbach-Mansky, R.1
Dailey, N.J.2
Canna, S.W.3
Al, E.4
-
39
-
-
0037007683
-
Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor alpha
-
Gorman JD, Sack KE, Davis JC, Jr., et al (2002). Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor alpha. N Engl J Med 346:1349 1356.
-
(2002)
N Engl J Med
, vol.346
, pp. 1349-1356
-
-
Gorman, J.D.1
Sack, K.E.2
Davis Jr., J.C.3
Al, E.4
-
40
-
-
21344465207
-
Correlation of serum B lymphocyte stimulator and beta2 microglobulin with autoantibody secretion and systemic involvement in primary Sjogren's syndrome
-
Gottenberg JE, Busson M, Cohen-Solal J, et al (2005a). Correlation of serum B lymphocyte stimulator and beta2 microglobulin with autoantibody secretion and systemic involvement in primary Sjogren's syndrome. Ann Rheum Dis 64:1050 1055.
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 1050-1055
-
-
Gottenberg, J.E.1
Busson, M.2
Cohen-Solal, J.3
Al, E.4
-
41
-
-
21144438589
-
Tolerance and short term efficacy of rituximab in 43 patients with systemic autoimmune diseases
-
Gottenberg JE, Guillevin L, Lambotte O, et al (2005b). Tolerance and short term efficacy of rituximab in 43 patients with systemic autoimmune diseases. Ann Rheum Dis 64:913 920.
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 913-920
-
-
Gottenberg, J.E.1
Guillevin, L.2
Lambotte, O.3
Al, E.4
-
43
-
-
0033808893
-
Cytokine production, serum levels and disease activity in systemic lupus erythematosus
-
Grondal G, Gunnarsson I, Ronnelid J, et al (2000). Cytokine production, serum levels and disease activity in systemic lupus erythematosus. Clin Exp Rheumatol 18:565 570.
-
(2000)
Clin Exp Rheumatol
, vol.18
, pp. 565-570
-
-
Grondal, G.1
Gunnarsson, I.2
Ronnelid, J.3
Al, E.4
-
44
-
-
0036144353
-
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome
-
Groom J, Kalled SL, Cutler AH, et al (2002). Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome. J Clin Invest 109:59 68.
-
(2002)
J Clin Invest
, vol.109
, pp. 59-68
-
-
Groom, J.1
Kalled, S.L.2
Cutler, A.H.3
Al, E.4
-
45
-
-
0036927904
-
Disseminated cytomegalovirus infection in Crohn's disease following anti-tumour necrosis factor therapy
-
Helbling D, Breitbach TH, Krause M, et al (2002). Disseminated cytomegalovirus infection in Crohn's disease following anti-tumour necrosis factor therapy. Eur J Gastroenterol Hepatol 14:1393 1395.
-
(2002)
Eur J Gastroenterol Hepatol
, vol.14
, pp. 1393-1395
-
-
Helbling, D.1
Breitbach, T.H.2
Krause, M.3
Al, E.4
-
46
-
-
0024269961
-
Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis
-
Hirano T, Matsuda T, Turner M, et al (1988). Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis. Eur J Immunol 18:1797 1801.
-
(1988)
Eur J Immunol
, vol.18
, pp. 1797-1801
-
-
Hirano, T.1
Matsuda, T.2
Turner, M.3
Al, E.4
-
47
-
-
0034677123
-
Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice
-
Horai R, Saijo S, Tanioka H, et al (2000). Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice. J Exp Med 191:313 320.
-
(2000)
J Exp Med
, vol.191
, pp. 313-320
-
-
Horai, R.1
Saijo, S.2
Tanioka, H.3
Al, E.4
-
48
-
-
0018110856
-
Excess risk of lymphomas, leukemia and myeloma in patients with rheumatoid arthritis
-
Isomaki HA, Hakulinen T, Joutsenlahti U, et al (1978). Excess risk of lymphomas, leukemia and myeloma in patients with rheumatoid arthritis. J Chronic Dis 31:691 696.
-
(1978)
J Chronic Dis
, vol.31
, pp. 691-696
-
-
Isomaki, H.A.1
Hakulinen, T.2
Joutsenlahti, U.3
Al, E.4
-
49
-
-
34249799278
-
Anakinra treatment in patients with adult-onset Still's disease is fast, effective, safe and steroid sparing: Experience from an uncontrolled trial
-
Kalliolias GD, Georgiou PE, Antonopoulos IA, et al (2007). Anakinra treatment in patients with adult-onset Still's disease is fast, effective, safe and steroid sparing: experience from an uncontrolled trial. Ann Rheum Dis 66:842 843.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 842-843
-
-
Kalliolias, G.D.1
Georgiou, P.E.2
Antonopoulos, I.A.3
Al, E.4
-
52
-
-
0026039673
-
Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
-
Keffer J, Probert L, Cazlaris H, et al (1991). Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J 10:4025 4031.
-
(1991)
EMBO J
, vol.10
, pp. 4025-4031
-
-
Keffer, J.1
Probert, L.2
Cazlaris, H.3
Al, E.4
-
53
-
-
0028540931
-
Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily
-
Kelm S, Pelz A, Schauer R, et al (1994). Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily. Curr Biol 4:965 972.
-
(1994)
Curr Biol
, vol.4
, pp. 965-972
-
-
Kelm, S.1
Pelz, A.2
Schauer, R.3
Al, E.4
-
54
-
-
2342658406
-
Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: A randomized, placebo-controlled, 52-week trial
-
Keystone EC, Kavanaugh AF, Sharp JT, et al (2004a). Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial. Arthritis Rheum 50:1400 1411.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1400-1411
-
-
Keystone, E.C.1
Kavanaugh, A.F.2
Sharp, J.T.3
Al, E.4
-
55
-
-
1042290332
-
Once-weekly administration of 50 mg etanercept in patients with active rheumatoid arthritis: Results of a multicenter, randomized, double-blind, placebo-controlled trial
-
Keystone EC, Schiff MH, Kremer JM, et al (2004b). Once-weekly administration of 50 mg etanercept in patients with active rheumatoid arthritis: results of a multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum 50:353 363.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 353-363
-
-
Keystone, E.C.1
Schiff, M.H.2
Kremer, J.M.3
Al, E.4
-
56
-
-
0028868424
-
CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system
-
Khoury SJ, Akalin E, Chandraker A, et al (1995). CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system. J Immunol 155:4521 4524.
-
(1995)
J Immunol
, vol.155
, pp. 4521-4524
-
-
Khoury, S.J.1
Akalin, E.2
Chandraker, A.3
Al, E.4
-
57
-
-
0038182745
-
A pilot study to test the efficacy of oral administration of interferon-alpha lozenges to patients with Sjogren's syndrome
-
Khurshudian AV (2003). A pilot study to test the efficacy of oral administration of interferon-alpha lozenges to patients with Sjogren's syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:38 44.
-
(2003)
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
, vol.95
, pp. 38-44
-
-
Khurshudian, A.V.1
-
58
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G, Milstein C (1975). Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256:495 497.
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
59
-
-
0242574700
-
Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig
-
Kremer JM, Westhovens R, Moreland LW, et al (2003). Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig. N Engl J Med 349:1907 1915.
-
(2003)
N Engl J Med
, vol.349
, pp. 1907-1915
-
-
Kremer, J.M.1
Westhovens, R.2
Moreland, L.W.3
Al, E.4
-
60
-
-
33745291091
-
Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: A randomized trial
-
Kremer JM, Genant HK, Leon M, et al (2006). Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: a randomized trial. Ann Intern Med 144:865 876.
-
(2006)
Ann Intern Med
, vol.144
, pp. 865-876
-
-
Kremer, J.M.1
Genant, H.K.2
Leon, M.3
Al, E.4
-
61
-
-
1842583827
-
Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjogren's syndrome
-
Lavie F, Miceli-Richard C, Quillard J, et al (2004). Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjogren's syndrome. J Pathol 202:496 502.
-
(2004)
J Pathol
, vol.202
, pp. 496-502
-
-
Lavie, F.1
Miceli-Richard, C.2
Quillard, J.3
Al, E.4
-
62
-
-
33747860018
-
Incidence of cancer in a cohort of patients with primary Sjogren's syndrome
-
Lazarus MN, Robinson D, Mak V, et al (2006). Incidence of cancer in a cohort of patients with primary Sjogren's syndrome. Rheumatology (Oxford) 45:1012 1015.
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 1012-1015
-
-
Lazarus, M.N.1
Robinson, D.2
Mak, V.3
Al, E.4
-
63
-
-
0036785351
-
Clinical outcome in 22 patients with rheumatoid arthritis treated with B lymphocyte depletion
-
Leandro MJ, Edwards JC, Edwards JC, et al (2002). Clinical outcome in 22 patients with rheumatoid arthritis treated with B lymphocyte depletion. Ann Rheum Dis 61:883 888.
-
(2002)
Ann Rheum Dis
, vol.61
, pp. 883-888
-
-
Leandro, M.J.1
Edwards, J.C.2
Edwards, J.C.3
Al, E.4
-
64
-
-
28544449032
-
B-cell depletion in the treatment of patients with systemic lupus erythematosus: A longitudinal analysis of 24 patients
-
Leandro MJ, Cambridge G, Cambridge G, et al (2005). B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients. Rheumatology (Oxford) 44:1542 1545.
-
(2005)
Rheumatology (Oxford)
, vol.44
, pp. 1542-1545
-
-
Leandro, M.J.1
Cambridge, G.2
Cambridge, G.3
Al, E.4
-
65
-
-
0036822552
-
Life-threatening histoplasmosis complicating immunotherapy with tumor necrosis factor alpha antagonists infliximab and etanercept
-
Lee JH, Slifman NR, Gershon SK, et al (2002). Life-threatening histoplasmosis complicating immunotherapy with tumor necrosis factor alpha antagonists infliximab and etanercept. Arthritis Rheum 46:2565 2570.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2565-2570
-
-
Lee, J.H.1
Slifman, N.R.2
Gershon, S.K.3
Al, E.4
-
66
-
-
0028900297
-
Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse
-
Lenschow DJ, Ho SC, Sattar H, et al (1995). Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. J Exp Med 181:1145 1155.
-
(1995)
J Exp Med
, vol.181
, pp. 1145-1155
-
-
Lenschow, D.J.1
Ho, S.C.2
Sattar, H.3
Al, E.4
-
67
-
-
0025990288
-
Elevated levels of endogenous IL-6 in systemic lupus erythematosus. a putative role in pathogenesis
-
Linker-Israeli M, Deans RJ, Wallace DJ, et al (1991). Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis. J Immunol 147:117 123.
-
(1991)
J Immunol
, vol.147
, pp. 117-123
-
-
Linker-Israeli, M.1
Deans, R.J.2
Wallace, D.J.3
Al, E.4
-
68
-
-
0034735842
-
Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group
-
Lipsky PE, van der Heijde DM, St Clair EW, et al (2000). Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N Engl J Med 343:1594 1602.
-
(2000)
N Engl J Med
, vol.343
, pp. 1594-1602
-
-
Lipsky, P.E.1
Van Der Heijde, D.M.2
St Clair, E.W.3
Al, E.4
-
69
-
-
4043179907
-
B cell depletion as a novel treatment for systemic lupus erythematosus: A phase I-/-II dose-escalation trial of rituximab
-
Looney RJ, Anolik JH, Campbell D, et al (2004). B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I-/-II dose-escalation trial of rituximab. Arthritis Rheum 50:2580 2589.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2580-2589
-
-
Looney, R.J.1
Anolik, J.H.2
Campbell, D.3
Al, E.4
-
70
-
-
0034673697
-
Etanercept in children with polyarticular juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group
-
Lovell DJ, Giannini EH, Reiff A, et al (2000). Etanercept in children with polyarticular juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group. N Engl J Med 342:763 769.
-
(2000)
N Engl J Med
, vol.342
, pp. 763-769
-
-
Lovell, D.J.1
Giannini, E.H.2
Reiff, A.3
Al, E.4
-
71
-
-
0027518860
-
Serum interleukin 6 levels in rheumatoid arthritis: Correlations with clinical and laboratory indices of disease activity
-
Madhok R, Crilly A, Watson J, et al (1993). Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity. Ann Rheum Dis 52:232 234.
-
(1993)
Ann Rheum Dis
, vol.52
, pp. 232-234
-
-
Madhok, R.1
Crilly, A.2
Watson, J.3
Al, E.4
-
72
-
-
0033524159
-
Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: A randomised phase III trial. ATTRACT Study Group
-
Maini R, St Clair EW, Breedveld F, et al (1999). Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group. Lancet 354:1932 1939.
-
(1999)
Lancet
, vol.354
, pp. 1932-1939
-
-
Maini, R.1
St Clair, E.W.2
Breedveld, F.3
Al, E.4
-
73
-
-
11144354315
-
Sustained improvement over two years in physical function, structural damage, and signs and symptoms among patients with rheumatoid arthritis treated with infliximab and methotrexate
-
Maini RN, Breedveld FC, Kalden JR, et al (2004). Sustained improvement over two years in physical function, structural damage, and signs and symptoms among patients with rheumatoid arthritis treated with infliximab and methotrexate. Arthritis Rheum 50:1051 1065.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1051-1065
-
-
Maini, R.N.1
Breedveld, F.C.2
Kalden, J.R.3
Al, E.4
-
74
-
-
33749363027
-
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate
-
Maini RN, Taylor PC, Szechinski J, et al (2006). Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate. Arthritis Rheum 54:2817 2829.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2817-2829
-
-
Maini, R.N.1
Taylor, P.C.2
Szechinski, J.3
Al, E.4
-
75
-
-
0037310430
-
The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjogren's syndrome
-
Mariette X, Roux S, Zhang J, et al (2003). The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjogren's syndrome. Ann Rheum Dis 62:168 171.
-
(2003)
Ann Rheum Dis
, vol.62
, pp. 168-171
-
-
Mariette, X.1
Roux, S.2
Zhang, J.3
Al, E.4
-
76
-
-
11144355974
-
Inefficacy of infliximab in primary Sjogren's syndrome: Results of the randomized, controlled Trial of Remicade in Primary Sjogren's Syndrome (TRIPSS)
-
Mariette X, Ravaud P, Steinfeld S, et al (2004). Inefficacy of infliximab in primary Sjogren's syndrome: results of the randomized, controlled Trial of Remicade in Primary Sjogren's Syndrome (TRIPSS). Arthritis Rheum 50:1270 1276.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1270-1276
-
-
Mariette, X.1
Ravaud, P.2
Steinfeld, S.3
Al, E.4
-
77
-
-
0025787402
-
Occurrence of neoplasia in patients with rheumatoid arthritis enrolled in a DMARD Registry. Rheumatoid Arthritis Azathioprine Registry Steering Committee
-
Matteson EL, Hickey AR, Maguire L, et al (1991). Occurrence of neoplasia in patients with rheumatoid arthritis enrolled in a DMARD Registry. Rheumatoid Arthritis Azathioprine Registry Steering Committee. J Rheumatol 18:809 814.
-
(1991)
J Rheumatol
, vol.18
, pp. 809-814
-
-
Matteson, E.L.1
Hickey, A.R.2
Maguire, L.3
Al, E.4
-
78
-
-
0034729950
-
Etanercept in the treatment of psoriatic arthritis and psoriasis: A randomised trial
-
Mease PJ, Goffe BS, Metz J, et al (2000). Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial. Lancet 356:385 390.
-
(2000)
Lancet
, vol.356
, pp. 385-390
-
-
Mease, P.J.1
Goffe, B.S.2
Metz, J.3
Al, E.4
-
79
-
-
0035674613
-
Demyelination occurring during anti-tumor necrosis factor alpha therapy for inflammatory arthritides
-
Mohan N, Edwards ET, Cupps TR, et al (2001). Demyelination occurring during anti-tumor necrosis factor alpha therapy for inflammatory arthritides. Arthritis Rheum 44:2862 2869.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 2862-2869
-
-
Mohan, N.1
Edwards, E.T.2
Cupps, T.R.3
Al, E.4
-
80
-
-
3943084864
-
Tuberculosis following the use of etanercept, a tumor necrosis factor inhibitor
-
Mohan AK, Cote TR, Block JA, et al (2004). Tuberculosis following the use of etanercept, a tumor necrosis factor inhibitor. Clin Infect Dis 39:295 299.
-
(2004)
Clin Infect Dis
, vol.39
, pp. 295-299
-
-
Mohan, A.K.1
Cote, T.R.2
Block, J.A.3
Al, E.4
-
81
-
-
0013511183
-
Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
-
Moreland LW, Baumgartner SW, Schiff MH, et al (1997). Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med 337:141 147.
-
(1997)
N Engl J Med
, vol.337
, pp. 141-147
-
-
Moreland, L.W.1
Baumgartner, S.W.2
Schiff, M.H.3
Al, E.4
-
82
-
-
0033574147
-
Etanercept therapy in rheumatoid arthritis. a randomized, controlled trial
-
Moreland LW, Schiff MH, Baumgartner SW, et al (1999). Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial. Ann Intern Med 130:478 486.
-
(1999)
Ann Intern Med
, vol.130
, pp. 478-486
-
-
Moreland, L.W.1
Schiff, M.H.2
Baumgartner, S.W.3
Al, E.4
-
83
-
-
84925549112
-
The paradigm of IL-6: From basic science to medicine
-
Naka T, Nishimoto N, Kishimoto T, et al (2002). The paradigm of IL-6: from basic science to medicine. Arthritis Res 4 (Suppl. 3 S233 S242.
-
(2002)
Arthritis Res
, vol.4
, Issue.3
-
-
Naka, T.1
Nishimoto, N.2
Kishimoto, T.3
Al, E.4
-
84
-
-
0036157807
-
Reactivation of histoplasmosis after treatment with infliximab
-
Nakelchik M, Mangino JE (2002). Reactivation of histoplasmosis after treatment with infliximab. Am J Med 112:78.
-
(2002)
Am J Med
, vol.112
, pp. 78
-
-
Nakelchik, M.1
Mangino, J.E.2
-
85
-
-
33646701639
-
Interleukin-6 in rheumatoid arthritis
-
Nishimoto N (2006). Interleukin-6 in rheumatoid arthritis. Curr Opin Rheumatol 18:277 281.
-
(2006)
Curr Opin Rheumatol
, vol.18
, pp. 277-281
-
-
Nishimoto, N.1
-
86
-
-
2642558925
-
Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: A multicenter, double-blind, placebo-controlled trial
-
Nishimoto N, Yoshizaki K, Miyasaka N, et al (2004). Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum 50:1761 1769.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1761-1769
-
-
Nishimoto, N.1
Yoshizaki, K.2
Miyasaka, N.3
Al, E.4
-
87
-
-
34447300492
-
Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): Evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab
-
Nishimoto N, Hashimoto J, Miyasaka N, et al (2007). Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab. Ann Rheum Dis 66:1162 1167.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 1162-1167
-
-
Nishimoto, N.1
Hashimoto, J.2
Miyasaka, N.3
Al, E.4
-
88
-
-
0033583479
-
Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
-
O'Keefe TL, Williams GT, Batista FD, et al (1999). Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J Exp Med 189:1307 1313.
-
(1999)
J Exp Med
, vol.189
, pp. 1307-1313
-
-
O'Keefe, T.L.1
Williams, G.T.2
Batista, F.D.3
Al, E.4
-
89
-
-
0030467610
-
CD22 regulates thymus-independent responses and the lifespan of B cells
-
Otipoby KL, Andersson KB, Draves KE, et al (1996). CD22 regulates thymus-independent responses and the lifespan of B cells. Nature 384:634 637.
-
(1996)
Nature
, vol.384
, pp. 634-637
-
-
Otipoby, K.L.1
Andersson, K.B.2
Draves, K.E.3
Al, E.4
-
90
-
-
0031781756
-
IL-1 receptor antagonist (IL-1RA) gene polymorphism in Sjogren's syndrome and rheumatoid arthritis
-
Perrier S, Coussediere C, Dubost JJ, et al (1998). IL-1 receptor antagonist (IL-1RA) gene polymorphism in Sjogren's syndrome and rheumatoid arthritis. Clin Immunol Immunopathol 87:309 313.
-
(1998)
Clin Immunol Immunopathol
, vol.87
, pp. 309-313
-
-
Perrier, S.1
Coussediere, C.2
Dubost, J.J.3
Al, E.4
-
91
-
-
0030457978
-
Serum and urinary interleukin-6 in systemic lupus erythematosus
-
Peterson E, Robertson AD, Emlen W, et al (1996). Serum and urinary interleukin-6 in systemic lupus erythematosus. Lupus 5:571 575.
-
(1996)
Lupus
, vol.5
, pp. 571-575
-
-
Peterson, E.1
Robertson, A.D.2
Emlen, W.3
Al, E.4
-
92
-
-
25444437442
-
Rituximab treatment in patients with primary Sjogren's syndrome: An open-label phase II study
-
Pijpe J, van Imhoff GW, Spijkervet FK, et al (2005). Rituximab treatment in patients with primary Sjogren's syndrome: an open-label phase II study. Arthritis Rheum 52:2740 2750.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2740-2750
-
-
Pijpe, J.1
Van Imhoff, G.W.2
Spijkervet, F.K.3
Al, E.4
-
93
-
-
0022996769
-
Taking mortality in rheumatoid arthritis seriously - Predictive markers, socioeconomic status and comorbidity
-
Pincus T, Callahan LF (1986). Taking mortality in rheumatoid arthritis seriously - predictive markers, socioeconomic status and comorbidity. J Rheumatol 13:841 845.
-
(1986)
J Rheumatol
, vol.13
, pp. 841-845
-
-
Pincus, T.1
Callahan, L.F.2
-
94
-
-
0021212076
-
Severe functional declines, work disability, and increased mortality in seventy-five rheumatoid arthritis patients studied over nine years
-
Pincus T, Callahan LF, Sale WG, et al (1984). Severe functional declines, work disability, and increased mortality in seventy-five rheumatoid arthritis patients studied over nine years. Arthritis Rheum 27:864 872.
-
(1984)
Arthritis Rheum
, vol.27
, pp. 864-872
-
-
Pincus, T.1
Callahan, L.F.2
Sale, W.G.3
Al, E.4
-
95
-
-
0033529049
-
Infliximab for the treatment of fistulas in patients with Crohn's disease
-
Present DH, Rutgeerts P, Targan S, et al (1999). Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med 340:1398 1405.
-
(1999)
N Engl J Med
, vol.340
, pp. 1398-1405
-
-
Present, D.H.1
Rutgeerts, P.2
Targan, S.3
Al, E.4
-
96
-
-
0028057250
-
Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20
-
Reff ME, Carner K, Chambers KS, et al (1994). Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood 83:435 445.
-
(1994)
Blood
, vol.83
, pp. 435-445
-
-
Reff, M.E.1
Carner, K.2
Chambers, K.S.3
Al, E.4
-
97
-
-
0035068351
-
Infliximab for Crohn's disease in clinical practice at the Mayo Clinic: The first 100 patients
-
Ricart E, Panaccione R, Loftus EV, et al (2001). Infliximab for Crohn's disease in clinical practice at the Mayo Clinic: the first 100 patients. Am J Gastroenterol 96:722 729.
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 722-729
-
-
Ricart, E.1
Panaccione, R.2
Loftus, E.V.3
Al, E.4
-
98
-
-
5044226801
-
Sensory neuropathy revealing necrotizing vasculitis during infliximab therapy for rheumatoid arthritis
-
Richette P, Dieude P, Damiano J, et al (2004). Sensory neuropathy revealing necrotizing vasculitis during infliximab therapy for rheumatoid arthritis. J Rheumatol 31:2079 2081.
-
(2004)
J Rheumatol
, vol.31
, pp. 2079-2081
-
-
Richette, P.1
Dieude, P.2
Damiano, J.3
Al, E.4
-
99
-
-
0022441214
-
Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage
-
Saklatvala J (1986). Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature 322:547 549.
-
(1986)
Nature
, vol.322
, pp. 547-549
-
-
Saklatvala, J.1
-
100
-
-
3142755717
-
Etanercept in Sjogren's syndrome: A twelve-week randomized, double-blind, placebo-controlled pilot clinical trial
-
Sankar V, Brennan MT, Kok MR, et al (2004). Etanercept in Sjogren's syndrome: a twelve-week randomized, double-blind, placebo-controlled pilot clinical trial. Arthritis Rheum 50:2240 2245.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2240-2245
-
-
Sankar, V.1
Brennan, M.T.2
Kok, M.R.3
Al, E.4
-
101
-
-
34047177483
-
Tolerance and efficacy of rituximab and changes in serum B cell biomarkers in patients with systemic complications of primary Sjogren's syndrome
-
Seror R, Sordet C, Guillevin L, et al (2007). Tolerance and efficacy of rituximab and changes in serum B cell biomarkers in patients with systemic complications of primary Sjogren's syndrome. Ann Rheum Dis 66:351 357.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 351-357
-
-
Seror, R.1
Sordet, C.2
Guillevin, L.3
Al, E.4
-
102
-
-
0027392629
-
A preliminary study on the interferon-alpha treatment for xerostomia of Sjogren's syndrome
-
Shiozawa S, Morimoto I, Tanaka Y, et al (1993). A preliminary study on the interferon-alpha treatment for xerostomia of Sjogren's syndrome. Br J Rheumatol 32:52 54.
-
(1993)
Br J Rheumatol
, vol.32
, pp. 52-54
-
-
Shiozawa, S.1
Morimoto, I.2
Tanaka, Y.3
Al, E.4
-
103
-
-
0031900178
-
Single-blinded controlled trial of low-dose oral IFN-alpha for the treatment of xerostomia in patients with Sjogren's syndrome
-
Shiozawa S, Tanaka Y, Shiozawa K, et al (1998). Single-blinded controlled trial of low-dose oral IFN-alpha for the treatment of xerostomia in patients with Sjogren's syndrome. J Interferon Cytokine Res 18:255 262.
-
(1998)
J Interferon Cytokine Res
, vol.18
, pp. 255-262
-
-
Shiozawa, S.1
Tanaka, Y.2
Shiozawa, K.3
Al, E.4
-
104
-
-
0033174272
-
Treatment of primary Sjogren's syndrome with low-dose natural human interferon-alpha administered by the oral mucosal route: A phase II clinical trial. IFN Protocol Study Group
-
Ship JA, Fox PC, Michalek JE, et al (1999). Treatment of primary Sjogren's syndrome with low-dose natural human interferon-alpha administered by the oral mucosal route: a phase II clinical trial. IFN Protocol Study Group. J Interferon Cytokine Res 19:943 951.
-
(1999)
J Interferon Cytokine Res
, vol.19
, pp. 943-951
-
-
Ship, J.A.1
Fox, P.C.2
Michalek, J.E.3
Al, E.4
-
105
-
-
33749331884
-
Long-term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: Remission, relapse, and re-treatment
-
Smith KG, Jones RB, Burns SM, et al (2006). Long-term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: remission, relapse, and re-treatment. Arthritis Rheum 54:2970 2982.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2970-2982
-
-
Smith, K.G.1
Jones, R.B.2
Burns, S.M.3
Al, E.4
-
106
-
-
8444239359
-
Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: A randomized, controlled trial
-
St Clair EW, van der Heijde DM, Smolen JS, et al (2004). Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial. Arthritis Rheum 50:3432 3443.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3432-3443
-
-
St Clair, E.W.1
Van Der Heijde, D.M.2
Smolen, J.S.3
Al, E.4
-
107
-
-
70350591584
-
Epratuzumab (humanized anti-CD22 antibody) in primary Sjogren's syndrome: An open-label phase I/II study
-
Steinfeld SD, Tant L, Burmester GR, et al (2006). Epratuzumab (humanized anti-CD22 antibody) in primary Sjogren's syndrome: an open-label phase I/II study. Arthritis Res Ther 8:R129.
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Steinfeld, S.D.1
Tant, L.2
Burmester, G.R.3
Al, E.4
-
108
-
-
2942752122
-
Rationale for interleukin-6 blockade in systemic lupus erythematosus
-
Tackey E, Lipsky PE, EIllei GG, et al (2004). Rationale for interleukin-6 blockade in systemic lupus erythematosus. Lupus 13:339 343.
-
(2004)
Lupus
, vol.13
, pp. 339-343
-
-
Tackey, E.1
Lipsky, P.E.2
Eillei, G.G.3
Al, E.4
-
109
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group
-
Targan SR, Hanauer SB, van Deventer SJ, et al (1997). A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 337:1029 1035.
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.3
Al, E.4
-
110
-
-
0030993376
-
CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling
-
Tedder TF, Tuscano J, Sato S, et al (1997). CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. Annu Rev Immunol 15:481 504.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 481-504
-
-
Tedder, T.F.1
Tuscano, J.2
Sato, S.3
Al, E.4
-
111
-
-
28744446703
-
Rituximab: A promising therapy in systemic lupus erythematosus
-
Thatayatikom A, White AJ (2006). Rituximab: a promising therapy in systemic lupus erythematosus. Autoimmun Rev 5:18 24.
-
(2006)
Autoimmun Rev
, vol.5
, pp. 18-24
-
-
Thatayatikom, A.1
White, A.J.2
-
112
-
-
33744503669
-
Lymphoma and other malignancies in primary Sjogren's syndrome: A cohort study on cancer incidence and lymphoma predictors
-
Theander E, Henriksson G, Ljungberg O, et al (2006). Lymphoma and other malignancies in primary Sjogren's syndrome: a cohort study on cancer incidence and lymphoma predictors. Ann Rheum Dis 65:796 803.
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 796-803
-
-
Theander, E.1
Henriksson, G.2
Ljungberg, O.3
Al, E.4
-
113
-
-
0031597373
-
Sjogren's syndrome: A community-based study of prevalence and impact
-
Thomas E, Hay EM, Hajeer A, et al (1998). Sjogren's syndrome: a community-based study of prevalence and impact. Br J Rheumatol 37:1069 1076.
-
(1998)
Br J Rheumatol
, vol.37
, pp. 1069-1076
-
-
Thomas, E.1
Hay, E.M.2
Hajeer, A.3
Al, E.4
-
114
-
-
0343384370
-
T cell attractant chemokine expression initiates lacrimal gland destruction in nonobese diabetic mice
-
Tornwall J, Lane TE, Fox RI, et al (1999). T cell attractant chemokine expression initiates lacrimal gland destruction in nonobese diabetic mice. Lab Invest 79:1719 1726.
-
(1999)
Lab Invest
, vol.79
, pp. 1719-1726
-
-
Tornwall, J.1
Lane, T.E.2
Fox, R.I.3
Al, E.4
-
115
-
-
34547907464
-
Immunomodulatory properties of mesenchymal stem cells: A review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005
-
Tyndall A, Walker UA, Cope A, et al (2007). Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005. Arthritis Res Ther 9:301.
-
(2007)
Arthritis Res Ther
, vol.9
, pp. 301
-
-
Tyndall, A.1
Walker, U.A.2
Cope, A.3
Al, E.4
-
116
-
-
0030981088
-
Tumour necrosis factor and Crohn's disease
-
Van Deventer SJ (1997). Tumour necrosis factor and Crohn's disease. Gut 40:443 448.
-
(1997)
Gut
, vol.40
, pp. 443-448
-
-
Van Deventer, S.J.1
-
117
-
-
0029050742
-
Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2)
-
van Dullemen HM, van Deventer SJ, Hommes DW, et al (1995). Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2). Gastroenterology 109:129 135.
-
(1995)
Gastroenterology
, vol.109
, pp. 129-135
-
-
Van Dullemen, H.M.1
Van Deventer, S.J.2
Hommes, D.W.3
Al, E.4
-
118
-
-
34047186008
-
T cell costimulation: A rational target in the therapeutic armamentarium for autoimmune diseases and transplantation
-
Vincenti F, Luggen M (2007). T cell costimulation: a rational target in the therapeutic armamentarium for autoimmune diseases and transplantation. Annu Rev Med 58:347 358.
-
(2007)
Annu Rev Med
, vol.58
, pp. 347-358
-
-
Vincenti, F.1
Luggen, M.2
-
119
-
-
0035810141
-
Invasive pulmonary aspergillosis associated with infliximab therapy
-
Warris A, Bjorneklett A, Gaustad P, et al (2001). Invasive pulmonary aspergillosis associated with infliximab therapy. N Engl J Med 344:1099 1100.
-
(2001)
N Engl J Med
, vol.344
, pp. 1099-1100
-
-
Warris, A.1
Bjorneklett, A.2
Gaustad, P.3
Al, E.4
-
120
-
-
0033611472
-
A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate
-
Weinblatt ME, Kremer JM, Bankhurst AD, et al (1999). A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 340:253 259.
-
(1999)
N Engl J Med
, vol.340
, pp. 253-259
-
-
Weinblatt, M.E.1
Kremer, J.M.2
Bankhurst, A.D.3
Al, E.4
-
121
-
-
0037231533
-
Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: The ARMADA trial
-
Weinblatt ME, Keystone EC, Furst DE, et al (2003). Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial. Arthritis Rheum 48:35 45.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 35-45
-
-
Weinblatt, M.E.1
Keystone, E.C.2
Furst, D.E.3
Al, E.4
-
122
-
-
33846853779
-
Selective costimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: A randomised clinical trial
-
Weinblatt M, Schiff M, Goldman A, et al (2007). Selective costimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: a randomised clinical trial. Ann Rheum Dis 66:228 234.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 228-234
-
-
Weinblatt, M.1
Schiff, M.2
Goldman, A.3
Al, E.4
-
123
-
-
0038721588
-
Efficacy, pharmacokinetic, and safety assessment of adalimumab, a fully human anti-tumor necrosis factor-alpha monoclonal antibody, in adults with rheumatoid arthritis receiving concomitant methotrexate: A pilot study
-
Weisman MH, Moreland LW, Furst DE, et al (2003). Efficacy, pharmacokinetic, and safety assessment of adalimumab, a fully human anti-tumor necrosis factor-alpha monoclonal antibody, in adults with rheumatoid arthritis receiving concomitant methotrexate: a pilot study. Clin Ther 25:1700 1721.
-
(2003)
Clin Ther
, vol.25
, pp. 1700-1721
-
-
Weisman, M.H.1
Moreland, L.W.2
Furst, D.E.3
Al, E.4
-
124
-
-
0026644298
-
Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
-
Williams RO, Feldmann M, Maini RN, et al (1992). Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci U S A 89:9784 9788.
-
(1992)
Proc Natl Acad Sci U S a
, vol.89
, pp. 9784-9788
-
-
Williams, R.O.1
Feldmann, M.2
Maini, R.N.3
Al, E.4
-
126
-
-
31544451391
-
Open label phase II trial of single, ascending doses of MRA in Caucasian children with severe systemic juvenile idiopathic arthritis: Proof of principle of the efficacy of IL-6 receptor blockade in this type of arthritis and demonstration of prolonged clinical improvement
-
Woo P, Wilkinson N, Prieur AM, et al (2005). Open label phase II trial of single, ascending doses of MRA in Caucasian children with severe systemic juvenile idiopathic arthritis: proof of principle of the efficacy of IL-6 receptor blockade in this type of arthritis and demonstration of prolonged clinical improvement. Arthritis Res Ther 7:R1281 R1288.
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Woo, P.1
Wilkinson, N.2
Prieur, A.M.3
Al, E.4
-
128
-
-
20144362101
-
Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis
-
Yokota S, Miyamae T, Imagawa T, et al (2005). Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 52:818 825.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 818-825
-
-
Yokota, S.1
Miyamae, T.2
Imagawa, T.3
Al, E.4
-
129
-
-
0035167632
-
Cutting edge: A role for B lymphocyte stimulator in systemic lupus erythematosus
-
Zhang J, Roschke V, Baker KP, et al (2001). Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 166:6 10.
-
(2001)
J Immunol
, vol.166
, pp. 6-10
-
-
Zhang, J.1
Roschke, V.2
Baker, K.P.3
Al, E.4
-
130
-
-
0038662940
-
Tumor necrosis factor inhibitor gene expression suppresses lacrimal gland immunopathology in a rabbit model of autoimmune dacryoadenitis
-
Zhu Z, Stevenson D, Schechter JE, et al (2003). Tumor necrosis factor inhibitor gene expression suppresses lacrimal gland immunopathology in a rabbit model of autoimmune dacryoadenitis. Cornea 22:343 351.
-
(2003)
Cornea
, vol.22
, pp. 343-351
-
-
Zhu, Z.1
Stevenson, D.2
Schechter, J.E.3
Al, E.4
|