T cell attractant chemokine expression initiates lacrimal gland destruction in nonobese diabetic mice

Laboratory Investigation

Volumn 79, Issue 12, 1999, Pages 1719-1726

  Törnwall, Jyrki ^a,b   Lane, Thomas E ^a   Fox, Robert I ^a   Fox, Howard S ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DIABETES MELLITUS; GENE DELETION; GENETIC TRANSCRIPTION; INFLAMMATORY CELL; LACRIMAL GLAND; LYMPHOCYTIC INFILTRATION; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SJOEGREN SYNDROME; T LYMPHOCYTE ACTIVATION;

ANIMALS; BASE SEQUENCE; CHEMOKINES, C; DNA PRIMERS; GENE EXPRESSION; LACRIMAL APPARATUS; LYMPHOKINES; MICE; MICE, INBRED NOD; PLATELET FACTOR 4; RANTES; RECEPTORS, CHEMOKINE; SIALOGLYCOPROTEINS;

EID: 0343384370     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Baggiolini M, Dewald B, and Moser B (1994). Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines. Adv Immunol 55:97-179.
2. Barnes DA, Tse J, Kaufhold M, Owen M, Hesselgesser J, Strieter R, Horuk R, and Perez HD (1998). Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model. J Clin Invest 101:2910-9.
3. Bonecchi R, Bianchi G, Bordignon PP, D'Ambrosio D, Lang R, Borsatti A, Sozzani S, Allavena P, Gray PA, Mantovani A, and Sinigaglia F (1998). Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med 187:129-34.
4. Cairns JS, and D'Souza MP (1998). Chemokines and HIV-1 second receptors: the therapeutic connection. Nat Med 4:563-8.
5. Clark-Lewis I, Kim KS, Rajarathnam K, Gong JH, Dewald B, Moser B, Baggiolini M, and Sykes BD (1995). Structure-activity relationships of chemokines. J Leukoc Biol 57:703-11.
6. Fox RI, and Kang HI (1992). Pathogenesis of Sjogren's syndrome. Rheum Dis Clin North Am 18:517-38.
7. Gong JH, Ratkay LG, Waterfield JD, and Clark-Lewis I (1997). An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model. J Exp Med 186:131-7.
8. Gottlieb PA, Rossini AA, and Mordes JP (1988). Approaches to prevention and treatment of IDDM in animal models. Diabetes Care 11(Suppl) 1:29-36.
9. Hang L, Haraoka M, Agace WW, Leffler H, Burdick M, Strieter R, and Svanborg C (1999). Macrophage inflammatory protein-2 is required for neutrophil passage across the epithelial barrier of the infected urinary tract. J Immunol 162:3037-44.
10. Humphreys-Beher MG, Hu Y, Nakagawa Y, Wang PL, and Purushotham KR (1994). Utilization of the non-obese diabetic (NOD) mouse as an animal model for the study of secondary Sjogren's syndrome. Adv Exp Med Biol 350:631-6.
11. Hunger RE, Carnaud C, Vogt I, and Mueller C (1998). Male gonadal environment paradoxically promotes dacryoadenitis in nonobese diabetic mice. J Clin Invest 101:1300-9.
12. Hunger RE, Muller S, Laissue JA, Hess MW, Carnaud C, Garcia I, and Mueller C (1996). Inhibition of submandibular and lacrimal gland infiltration in nonobese diabetic mice by transgenic expression of soluble TNF-receptor p55. J Clin Invest 98:954-61.
13. Karpus WJ, Lukacs NW, McRae BL, Strieter RM, Kunkel SL, and Miller SD (1995). An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J Immunol 155:5003-10.
14. Kelner GS, Kennedy J, Bacon KB, Kleyensteuber S, Largaespada DA, Jenkins NA, Copeland NG, Bazan JF, Moore KW, Schall TJ, and Zlotnik A (1994). Lymphotactin: a cytokine that represents a new class of chemokine. Science 266:1395-9.
15. Kennedy KJ, Strieter RM, Kunkel SL, Lukacs NW, and Karpus WJ (1998). Acute and relapsing experimental autoimmune encephalomyelitis are regulated by differential expression of the CC chemokines macrophage inflammatory protein-1 alpha and monocyte chemotactic protein-1. J Neuroimmunol 92:98-108.
16. Lane TE, Asensio VC, Yu N, Paoletti AD, Campbell IL, and Buchmeier MJ (1998). Dynamic regulation of alpha-and beta-chemokine expression in the central nervous system during mouse hepatitis virus-induced demyelinating disease. J Immunol 160:970-8.
17. Littman DR (1998). Chemokine receptors: keys to AIDS pathogenesis? Cell 93:677-80.
18. Liu R, Paxton WA, Choe S, Ceradini D, Martin SR, Horuk R, MacDonald ME, Stuhlmann H, Koup RA, and Landau NR (1996). Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86:367-77.
19. Loetscher M, Gerber B, Loetscher P, Jones SA, Piali L, Clark-Lewis I, Baggiolini M, and Moser B. (1996a). Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med 184:963-9.
20. Loetscher P, Seitz M, Baggiolini M, and Moser B. (1996b). Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J Exp Med 184:569-77.
21. Miyagawa J, Hanafusa T, Miyazaki A, Yamada K, Fujino-Kurihara H, Nakajima H, Kono N, Nonaka K, Tochino Y, and Tarui S (1986). Ultrastructural and immunocytochemical aspects of lymphocytic submandibulitis in the non-obese diabetic (NOD) mouse. Virchows Arch B Cell Pathol Incl Mol Pathol 51:215-25.
22. Mustafa W, Sharafeldin A, Diab A, Huang YM, Bing H, Zhu J, Link H, Frithiof L, and Klinge B (1998). Coordinate up-regulation of the beta-chemokine subfamily in autoimmune sialoadenitis of MRL/lpr mice. Scand J Immunol 48:623-8.
23. Ohmori Y, and Hamilton TA (1995). The interferon-stimulated response element and a kappa B site mediate synergistic induction of murine IP-10 gene transcription by IFN-gamma and TNF-alpha. J Immunol 154:5235-44.
24. Plater-Zyberk C, Hoogewerf AJ, Proudfoot AE, Power CA, and Wells TN (1997). Effect of a CC chemokine receptor antagonist on collagen induced arthritis in DBA/1 mice. Immunol Lett 57:117-20.
25. Qin S, Rottman JB, Myers P, Kassam N, Weinblatt M, Loetscher M, Koch AE, Moser B, and Mackay CR (1998). The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J Clin Invest 101:746-54.
26. Taguchi M, Sampath D, Koga T, Castro M, Look DC, Nakajima S, and Holtzman MJ (1998). Patterns for RANTE S secretion and intercellular adhesion molecule 1 expression mediate transepithelial T cell traffic based on analyses in vitro and in vivo. J Exp Med 187:1927-40.
27. Taub DD, Lloyd AR, Conlon K, Wang JM, Ortaldo JR, Harada A, Matsushima K, Kelvin DJ, and Oppenheim JJ (1993). Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J Exp Med 177:1809-14.
28. Taub DD and Oppenheim JJ (1994). Chemokines, inflammation and the immune system. Ther Immunol 1:229-46.
29. Wu X, Wittwer AJ, Carr LS, Crippes BA, DeLarco JE, and Lefkowith JB (1994). Cytokine-induced neutrophil chemoattractant mediates neutrophil influx in immune complex glomerulonephritis in rat. J Clin Invest 94:337-44.
30. Yanagi K, Ishimaru N, Haneji N, Saegusa K, Saito I, and Hayashi Y (1998). Anti-120-kDa alpha-fodrin immune response with Th1-cytokine profile in the NOD mouse model of Sjogren's syndrome. Eur J Immunol 28:3336-45.