Suppression of tumor necrosis factor α-induced matrix metalloproteinase 9 production in human salivary gland acinar cells by cepharanthine occurs via down-regulation of nuclear factor κB: A possible therapeutic agent for preventing the destruction of the acinar structure in the salivary glands of Sjögren's syndrome patients

Arthritis and Rheumatism

Volumn 46, Issue 6, 2002, Pages 1585-1594

  Azuma, Masayuki ^a   Aota, Keiko ^a   Tamatani, Tetsuya ^a   Motegi, Katsumi ^a   Yamashita, Tsuyoshi ^a   Ashida, Yuki ^a   Hayashi, Yoshio ^a   Sato, Mitsunobu ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CEPHARANTHINE; COLLAGEN TYPE 4; GELATINASE B; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PLASMIN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROTECTION; CELL STRUCTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME REPRESSION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MORPHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SALIVARY GLAND; SJOEGREN SYNDROME;

ALKALOIDS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBODIES; CELL DIVISION; CELLS, CULTURED; COLLAGEN TYPE II; DNA-BINDING PROTEINS; DOWN-REGULATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; I-KAPPA B PROTEINS; MATRIX METALLOPROTEINASE 9; NF-KAPPA B; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; SALIVARY GLANDS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036272696     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10315     Document Type: Article

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