Reprint of "Stereology meets electron tomography: towards quantitative 3D electron microscopy" [J. Struct. Biol. 159 (2007) 443-450]

Journal of Structural Biology

Volumn 161, Issue 3, 2008, Pages 314-321

  Vanhecke, Dimitri ^a   Studer, Daniel ^a   Ochs, Matthias ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Cavalieri principle; Depth of field; Disector; Electron tomography; Overprojection; Quantification; Stereology; Transmission electron microscopy

Indexed keywords

ARTICLE; CONTROLLED STUDY; ELECTRON BEAM TOMOGRAPHY; ELECTRON MICROSCOPY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STEREOMETRY; SYMBIOSIS; THREE DIMENSIONAL IMAGING; TISSUE SECTION;

HUMANS; IMAGING, THREE-DIMENSIONAL; LUNG; MICROSCOPY, ELECTRON, TRANSMISSION; STEREOTAXIC TECHNIQUES;

RICHES;

EID: 40749085722     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/S1047-8477(08)00061-0     Document Type: Article

References (51)

1. Al-Amoudi A., Studer D., and Dubochet J. Cutting artifacts and cutting process in vitreous sections for cryo-electron microscopy. J. Struct. Biol. 150 (2005) 109-121
2. Aydinli B., Kantarci M., Polat K.Y., Unal B., Atamanalp S.S., Durur I., Unal D., and Akgun M. Stereological evaluation of treatment response in patients with non-resectable hepatic alveolar echinococcosis using computed tomography via the Cavalieri method. Liver Int. 26 (2006) 1234-1240
3. Baddeley A.J., and Vedel Jensen E.B. Stereology for Statisticians (2005), Chapman and Hall, Boca Raton, Florida, USA
4. Batson P.E., Dellby N., and Krivanek O.L. Sub-ångstrom resolution using aberration corrected electron optics. Nature 418 (2002) 617-620
5. Borisevich A.Y., Lupini A.R., and Pennycook S.J. Depth sectioning with the aberration-corrected scanning transmission electron microscope. Proc. Natl. Acad. Sci. USA 103 (2006) 3044-3048
6. Cruz-Orive L.M., and Weibel E.R. Sampling designs for stereology. J. Micrsoc. 122 (1981) 235-257
7. Dorph-Petersen K.A., Nyengaard J.R., and Gundersen H.J.G. Tissue shrinkage and unbiased stereological estimation of particle and size. J. Microsc. 204 (2001) 232-246
8. Fehrenbach H., and Ochs M. Studying lung ultrastructure. In: Uhlig S., and Taylor A.E. (Eds). Methods in Pulmonary Research (1998), Birkhäuser, Basel 429-454
9. Fehrenbach H., Schmiedl A., Wahlers T., Hirt S.W., Brasch F., Riemann D., and Richter J. Morphometric characterization of the fine-structure of human type-II pneumocytes. Anat. Rec. 243 (1995) 49-62
10. Fehrenbach H., Wahlers T., Ochs M., Brasch F., Schmiedl A., Hirt S.W., Haverich A., and Richter J. Ultrastructural pathology of the alveolar type II pneumocytes of human donor lungs - Electron microscopy, stereology, and microanalysis. Virchows Arch. 432 (1998) 229-239
11. Frank J. Electron tomography: three-dimensional imaging with the transmission electron microscope. first ed. (1992), Plenum Press, New York
12. Frank J. Electron tomography: methods for three-dimensional visualization of structures in the cell. second ed. (2006), Springer, New York
13. Freitag B., Kujawa S., Mul P.M., Ringnalda J., and Tiemeijer P.C. Breaking the spherical and chromatic aberration barrier in transmission electron microscopy. Ultramicroscopy 102 (2005) 209-214
14. Gardella D., Hatton W.J., Rind H.B., Rosen G.D., and von Bartheld C.S. Differential tissue shrinkage and compression in the z-axis: implications for optical disector counting in vibratome-, plastic- and cryosections. J. Neurosci. Methods 124 (2003) 45-59
15. Gundersen H.J.G., and Østerby R. Optimizing sampling efficiency of stereological studies in biology: or "Do more, less well". J. Microsc. 121 (1981) 65-73
16. Gundersen H.J.G., Boysen M., and Reith A. Comparison of semiautomatic digitizer-tablet and simple point counting performance in morphometry. Virchows Arch. B 37 (1981) 317-325
17. Gundersen H.J.G., and Jensen E.B. The efficiency of systematic sampling in stereology and its prediction. J. Microsc. 147 (1987) 229-263
18. Gundersen H.J.G., Bendtsen T.F., Korbo L., Marcussen N., Møller A., Nielsen K., Nyengaard J.R., Pakkenberg B., Sørensen F.B., Vesterby A., and West M.J. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96 (1988) 379-394
19. Gundersen H.J.G., Bagger P., Bendtsen T.F., Evans S.M., Korbo L., Marcussen N., Møller A., Nielsen K., Nyengaard J.R., Pakkenberg B., Sørensen F.B., Vesterby A., and West M.J. The new stereological tools: disector, fractionator, nucleator and point sampling intercepts and their use in pathological research and diagnosis. APMIS 96 (1988) 587-881
20. Gundersen H.J.G., Jensen E.B.V., Kieu K., and Nielsen J. The efficiency of systematic sampling in stereology-reconsidered. J. Micrsoc. 193 (1999) 199-211
21. Howard C.V., and Reed M.G. Unbiased Stereology: Three-dimensional Measurement in Microscopy. second ed. (2005), BIOS scientific publishers, Abingdon, UK
22. Haider M., Uhlemann S., Schwan E., Rose H., Kabius B., and Urban K. Electron microscopy image enhanced. Nature 392 (1998) 768-769
23. Hehl A.B., and Marti M. Secretory protein trafficking in Giardia intestinalis. Mol. Microbiol. 53 (2004) 19-28
24. Jastrow H.J., Von Mach M.A., and Vollrath L. Adaptation of the disector method to rare small organelles in TEM sections exemplified by counting synaptic bodies in the rat pineal gland. J. Anat. 191 (1997) 399-405
25. Jung A., Allen L., Nyengaard J.R., Gundersen H.J.G., Richter J., Hawgood S., and Ochs M. Design-based stereological analysis of the lung parenchymal architecture and alveolar type II cells in surfactant protein A and D double deficient mice. Anat. Rec. 286 (2005) 885-890
26. Kroustrup J.P., and Gundersen H.J.G. Estimating the number of complex particles using the ConnEulor principle. J. Microsc. 203 (2001) 314-320
27. Liu C., Edwards S., Gong Q., Roberts N., and Blumhardt L.D. Three dimensional MRI estimates of brain and spinal chord atrophy in multiple sclerosis. J. Neurol. Neurosurg. Psychiatry 66 (1999) 323-330
28. Lučić V., Förster F., and Baumeister W. Structural studies by electron tomography: from cells to molecules. Annu. Rev. Biochem. 74 (2005) 833-865
29. Mathieu O., Cruz-Orive L.M., Hoppeler H., and Weibel E.R. Measuring error and sampling variation in stereology: comparison of the efficiency of various methods for planar image analysis. J. Microsc. 121 (1981) 75-88
30. Mayhew T.M. The new stereological tools for interpreting functional morphology from slices of cells and organs. Exp. Physiol. 76 (1991) 639-665
31. McEwen B.F., and Marko M. The emergence of electron tomography as an important tool for investigating cellular ultrastructure. J. Histochem. Cytochem. 49 (2001) 553-563
32. Messaoudi, C., Halary, S., Sorzano, C.O.S., Marco, S., Boudier, T., 2006. TomoJ: new tools for electron tomography. In: Proceedings of the 1st ImageJ User and Developer Conference, Luxembourg.
33. Mironov A.A., and Mironov Jr. A.A. Estimation of subcellular organelle volume from ultrathin sections through centrioles with a discretized version of the vertical rotator. J. Microsc. 192 (1998) 29-36
34. Ochs M., Nyengaard J.R., Jung A., Knudsen L., Voigt M., Wahlers T., Richter J., and Gundersen H.J.G. The number of alveoli in the human lung. Am. J. Respir. Crit. Care Med. 169 (2004) 120-124
35. Ochs M., Knudsen L., Allen L., Stumbaugh A., Levitt S., Nyengaard J.R., and Hawgood S. GM-CSF mediates alveolar epithelial type II cell changes, but not emphysema-like pathology, in SP-D-deficient mice. Am. J. Physiol. Lung Cell. Mol. Physiol. 287 (2004) L1333-L1341
36. Ochs M. A brief update on lung stereology. J. Microsc. 222 (2006) 188-200
37. Roberts N., Puddephat M.J., and McNulty V. The benefit of stereology for quantitative radiology. Br. J. Radiol. 73 (2000) 679-697
38. Ress D.B., Harlow M.L., Marshall R.M., and McMahan U.J. Methods for generating high-resolution structural models from electron microscope tomography data. Structure 12 (2004) 1763-1774
39. Richter T., Biel S.S., Sattler M., Wenck H., Wittern K.P., Wiesendanger R., and Wepf R. Pros and cons: cryo-electron microscopic evaluation of block faces versus cryo-sections from frozen-hydrated skin specimens prepared by different techniques. J. Microsc. 225 (2007) 201-207
40. Sjöstrand, F.S., 1967. Electron Microscopy of Cells and Tissue: Instrumentation and Techniques, vol. 1. Academic press, New York, p. 119.
41. Sterio D.C. The unbiased estimation of number and sizes of arbitrary particles using the disector. J. Microsc. 134 (1984) 127-136
42. Studer D., and Gnaegi H. Minimal compression of ultrathin sections with use of an oscillating diamond knife. J. Microsc. 197 (2000) 94-100
43. Tang Y., Nyengaard J.R., De Groot D., and Gundersen HJG. Total regional and global number of synapses in the human brain neocortex. Synapse 41 (2001) 258-273
44. Vanhecke, D., Ochs, M., in press. Counting in nano: optical sectioning at the electron microscopic level. Microsc. Microanal. Suppl. 12.
45. Van Vré E.A., Van Beusekom H.M., Vrints C.J., Bosmans J.M., Bult H., and Van der Giessen W.J. Stereology: a simplified and more time-efficient method than planimetry for the quantitative analysis of vascular structures in different models of intimal thickening. Cardiovasc. Pathol. 16 (2007) 43-50
46. Webb R.H. Theoretical basis of confocal microscopy. In: Conn P.M. (Ed). Methods in Enzymology: Confocal Microscopy vol. 307 (1999), Academic press, San Diego 3-20
47. Weibel E.R. Principles and methods for the morphometric study of the lung and other organs. Lab. Invest. 12 (1963) 131-155
48. Weibel, E.R., 1979. Stereological Methods: Practical Methods for Biological Morphometry, vol. 1. Academic Press, London.
49. Weibel, E.R., 1980. Stereological Methods: Theoretical Foundations, vol. 2. Academic Press, London.
50. Weibel E.R., Hsia C.C.W., and Ochs M. How much is there really? Why stereology is essential in lung morphometry. J. Appl. Physiol. 102 (2007) 459-567
51. West M.J., and Gundersen H.J.G. Unbiased stereological estimation of the number of neurons in the human hippocampus. J. Comp. Neurol. 296 (1990) 1-22