Presentation of lipid antigens to T cells

Immunology Letters

Volumn 117, Issue 1, 2008, Pages 1-8

  Mori, Lucia ^a   De Libero, Gennaro ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Antigen presentation; CD1; Lipid antigens; T cells

Indexed keywords

APOLIPOPROTEIN A; HIGH DENSITY LIPOPROTEIN; LIPOARABINOMANNAN; VERY LOW DENSITY LIPOPROTEIN;

ANTIBODY RESPONSE; ANTIGEN RECOGNITION; AUTOIMMUNITY; CELL METABOLISM; IMMUNOGENICITY; IMMUNOREGULATION; LIPID TRANSPORT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; REVIEW; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; ANTIGENS, CD1; HUMANS; LIPIDS; T-LYMPHOCYTES;

EID: 40649118463     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2007.11.027     Document Type: Review

References (76)

1. van den Elzen P., Garg S., Leon L., Brigl M., Leadbetter E.A., Gumperz J.E., et al. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature 437 (2005) 906-910
2. Wu D.Y., Segal N.H., Sidobre S., Kronenberg M., and Chapman P.B. Cross-presentation of disialoganglioside GD3 to natural killer T cells. J Exp Med 198 (2003) 173-181
3. Schaible U.E., Winau F., Sieling P.A., Fischer K., Collins H.L., Hagens K., et al. Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis. Nat Med 9 (2003) 1039-1046
4. Winau F., Weber S., Sad S., de Diego J., Hoops S.L., Breiden B., et al. Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis. Immunity 24 (2006) 105-117
5. Jeon H., and Blacklow S.C. Structure and physiologic function of the low-density lipoprotein receptor. Annu Rev Biochem 74 (2005) 535-562
6. Sharma D.K., Choudhury A., Singh R.D., Wheatley C.L., Marks D.L., and Pagano R.E. Glycosphingolipids internalized via caveolar-related endocytosis rapidly merge with the clathrin pathway in early endosomes and form microdomains for recycling. J Biol Chem 278 (2003) 7564-7572
7. Pelkmans L., Burli T., Zerial M., and Helenius A. Caveolin-stabilized membrane domains as multifunctional transport and sorting devices in endocytic membrane traffic. Cell 118 (2004) 767-780
8. Tailleux L., Schwartz O., Herrmann J.L., Pivert E., Jackson M., Amara A., et al. DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells. J Exp Med 197 (2003) 121-127
9. Ernst W.A., Maher J., Cho S., Niazi K.R., Chatterjee D., Moody D.B., et al. Molecular interaction of CD1b with lipoglycan antigens. Immunity 8 (1998) 331-340
10. PrigozyTI, Naidenko O., Qasba P., Elewaut D., Brossay L., Khurana A., et al. Glycolipid antigen processing for presentation by CD1d molecules. Science 291 (2001) 664-667
11. Zhou D., Mattner J., Cantu III C., Schrantz N., Yin N., Gao Y., et al. Lysosomal glycosphingolipid recognition by NKT cells. Science 306 (2004) 1786-1789
12. de la Salle H., Mariotti S., Angenieux C., Gilleron M., Garcia-Alles L.F., Malm D., et al. Assistance of microbial glycolipid antigen processing by CD1e. Science 310 (2005) 1321-1324
13. Gilleron M., Ronet C., Mempel M., Monsarrat B., Gachelin G., and Puzo G. Acylation state of the phosphatidylinositol mannosides from Mycobacterium bovis bacillus Calmette Guerin and ability to induce granuloma and recruit natural killer T cells. J Biol Chem 276 (2001) 34896-34904
14. Sieling P.A., Chatterjee D., Porcelli S.A., Prigozy T.I., Mazzaccaro R.J., Soriano T., et al. CD 1-restricted T cell recognition of microbial lipoglycan antigens. Science 269 (1995) 227-230
15. Angenieux C., Salamero J., Fricker D., Cazenave J.P., Goud B., Hanau D., et al. Characterization of CD1e, a third type of CD1 molecule expressed in dendritic cells. J Biol Chem 275 (2000) 37757-37764
16. Sugita M., Porcelli S.A., and Brenner M.B. Assembly and retention of CD1b heavy chains in the endoplasmic reticulum. J Immunol 159 (1997) 2358-2365
17. 2-microglobulin. Int Immunol 11 (1999) 1615-1623
18. Kang S.J., and Cresswell P. Calnexin, calreticulin, and ERp57 cooperate in disulfide bond formation in human CD1d heavy chain. J Biol Chem 277 (2002) 44838-44844
19. De Silva A.D., Park J.J., Matsuki N., StanicAK, Brutkiewicz R.R., Medof M.E., et al. Lipid protein interactions: the assembly of CD1d1 with cellular phospholipids occurs in the endoplasmic reticulum. J Immunol 168 (2002) 723-733
20. Jayawardena-Wolf J., and Bendelac A. CD1 and lipid antigens: intracellular pathways for antigen presentation. Curr Opin Immunol 13 (2001) 109-113
21. Briken V., Jackman R.M., Dasgupta S., Hoening S., and Porcelli S.A. Intracellular trafficking pathway of newly synthesized CD1b molecules. Embo J 21 (2002) 825-834
22. Jayawardena-Wolf J., Benlagha K., Chiu Y.H., Mehr R., and Bendelac A. CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain. Immunity 15 (2001) 897-908
23. Kang S.J., and Cresswell P. Regulation of intracellular trafficking of human CD1 d by association with MHC class II molecules. Embo J 21 (2002) 1650-1660
24. Yuan W., Dasgupta A., and Cresswell P. Herpes simplex virus evades natural killer T cell recognition by suppressing CD1d recycling. Nat Immunol 7 (2006) 835-842
25. Brigl M., and Brenner M.B. CD1: antigen presentation and T cell function. Annu Rev Immunol 22 (2004) 817-890
26. Sugita M., Cernadas M., and Brenner M.B. New insights into pathways for CD1-mediated antigen presentation. Curr Opin Immunol 16 (2004) 90-95
27. Sugita M., Peters P.J., and Brenner M.B. Pathways for lipid antigen presentation by CD1 molecules: nowhere for intracellular pathogens to hide. Traffic 1 (2000) 295-300
28. Angenieux C., Fraisier V., Maitre B., Racine V., van der Wel N., Fricker D., et al. The cellular pathway of CD1e in immature and maturing dendritic cells. Traffic 6 (2005) 286-302
29. Zajonc D.M., Elsliger M.A., Teyton L., and Wilson I.A. Crystal structure of CD1 a in complex with a sulfatide self antigen at a resolution of 2.15 A. Nat Immunol 4 (2003) 808-815
30. Manolova V., Kistowska M., Paoletti S., Baltariu G.M., Bausinger H., Hanau D., et al. Functional CD1a is stabilized by exogenous lipids. Eur J Immunol 36 (2006) 1083-1092
31. Sanchez D.J., Gumperz J.E., and Ganem D. Regulation of CD1d expression and function by a herpesvirus infection. J Clin Invest 115 (2005) 1369-1378
32. Shinya E., Owaki A., Shimizu M., Takeuchi J., Kawashima T., Hidaka C., et al. Endogenously expressed HIV-1 nef down-regulates antigen-presenting molecules, not only class I MHC but also CD1a, in immature dendritic cells. Virology 326 (2004) 79-89
33. Mariotti S., Teloni R., Iona E., Fattorini L., Giannoni F., Romagnoli G., et al. Mycobacterium tuberculosis subverts the differentiation of human monocytes into dendritic cells. Eur J Immunol 32 (2002) 3050-3058
34. Amprey J.L., Spath G.F., and Porcelli S.A. Inhibition of CD1 expression in human dendritic cells during intracellular infection with Leishmania donovani. Infect Immun 72 (2004) 589-592
35. Kawana K., Quayle A.J., Ficarra M., Ibana J.A., Shen L., Kawana Y., et al. CD1d degradation in Chlamydia trachomatis-infected epithelial cells is the result of both cellular and chlamydial proteasomal activity. J Biol Chem 282 (2007) 7368-7375
36. Sprong H., van der Sluijs P., and van Meer G. How proteins move lipids and lipids move proteins. Nat Rev Mol Cell Biol 2 (2001) 504-513
37. Strauss III J.F., Kishida T., Christenson L.K., Fujimoto T., and Hiroi H. START domain proteins and the intracellular trafficking of cholesterol in steroidogenic cells. Mol Cell Endocrinol 202 (2003) 59-65
38. Mukherjee S., and Maxfield F.R. Lipid and cholesterol trafficking in NPC. Biochim Biophys Acta 1685 (2004) 28-37
39. Sagiv Y., Hudspeth K., Mattner J., Schrantz N., Stern R.K., Zhou D., et al. Cutting edge: impaired glycosphingolipid trafficking and NKT cell development in mice lacking Niemann-Picktype C1 protein. J Immunol 177 (2006) 26-30
40. Gadola S.D., Silk J.D., Jeans A., Illarionov P.A., Salio M., Besra G.S., et al. Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases. J Exp Med 203 (2006) 2293-2303
41. Schumann J., Facciotti F., Panza L., Michieletti M., Compostella F., Collmann A., et al. Differential alteration of lipid antigen presentation to NKT cells due to imbalances in lipid metabolism. Eur J Immunol 37 (2007) 1431-1441
42. Routt S.M., and Bankaitis V.A. Biological functions of phosphatidylinositol transfer proteins. Biochem Cell Biol 82 (2004) 254-262
43. Riezman H., and van Meer G. Lipid pickup and delivery. Nat Cell Biol 6 (2004) 15-16
44. Albers J.J., and Cheung M.C. Emerging roles for phospholipid transfer protein in lipid and lipoprotein metabolism. Curr Opin Lipidol 15 (2004) 255-260
45. Moody D.B., Briken V., Cheng T.Y., Roura-Mir C., Guy M.R., Geho D.H., et al. Lipid length controls antigen entry into endosomal and non-endosomal pathways for CD1b presentation. Nat Immunol 3 (2002) 435-442
46. Beatty W.L., Rhoades E.R., Ullrich H.J., Chatterjee D., Heuser J.E., and Russell D.G. Trafficking and release of mycobacterial lipids from infected macrophages. Traffic 1 (2000) 235-247
47. Schaible U.E., Hagens K., Fischer K., Collins H.L., and Kaufmann S.H. Intersection of group I CD1 molecules and mycobacteria in different intracellular compartments of dendritic cells. J Immunol 164 (2000) 4843-4852
48. Zeng Z., Castano A.R., Segelke B.W., Stura E.A., Peterson P.A., and Wilson I.A. Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove. Science 277 (1997) 339-345
49. Garcia-Alles L.F., Versluis K., Maveyraud L., Vallina A.T., Sansano S., Bello N.F., et al. Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b. Embo J 25 (2006) 3684-3692
50. Giabbai B., Sidobre S., Crispin M.D., Sanchez-Ruiz Y., Bachi A., Kronenberg M., et al. Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: a molecular basis for NKT cell activation. J Immunol 175 (2005) 977-984
51. Kang S.J., and Cresswell P. Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells. Nat Immunol 5 (2004) 175-181
52. Winau F., Schwierzeck V., Hurwitz R., Remmel N., Sieling P.A., Modlin R.L., et al. Saposin C is required for lipid presentation by human CD1b. Nat Immunol 5 (2004) 169-174
53. Zhou D., Cantu III C., Sagiv Y., Schrantz N., Kulkarni A.B., Qi X., et al. Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins. Science 303 (2004) 523-527
54. Schrantz N., Sagiv Y., Liu Y., Savage P.B., Bendelac A., and Teyton L. The Niemann-Picktype C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cells. J Exp Med 204 (2007) 841-852
55. Brozovic S., Nagaishi T., Yoshida M., Betz S., Salas A., Chen D., et al. CD1d function is regulated by microsomal triglyceride transfer protein. Nat Med 10 (2004) 535-539
56. Dougan S.K., Salas A., Rava P., Agyemang A., Kaser A., Morrison J., et al. Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells. J Exp Med 202 (2005) 529-539
57. Shamshiev A., Gober H.J., Donda A., Mazorra Z., Mori L., and De Libero G. Presentation of the same glycolipid by different CD1 molecules. J Exp Med 195 (2002) 1013-1021
58. Lanzavecchia A., Reid P.A., and Watts C. Irreversible association of peptides with class II MHC molecules in living cells. Nature 357 (1992) 249-252
59. Shamshiev A., Donda A., Carena I., Mori L., Kappos L., and De Libero G. Self glycolipids as T-cell autoantigens. Eur J Immunol 29 (1999) 1667-1675
60. Shamshiev A., Donda A., Prigozy T.I., Mori L., Chigorno V., Benedict C.A., et al. The αβ T cell response to self-glycolipids shows a novel mechanism of CD1b loading and a requirement for complex oligosaccharides. Immunity 13 (2000) 255-264
61. Rauch J., Gumperz J., Robinson C., Skold M., Roy C., Young D.C., et al. Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD 1d-restricted invariant NKT (iNKT) cell. J Biol Chem 278 (2003) 47508-47515
62. Gumperz J.E., Roy C., Makowska A., Lum D., Sugita M., Podrebarac T., et al. Murine CD1 d-restricted T cell recognition of cellular lipids. Immunity 12 (2000) 211-221
63. Agea E., Russano A., Bistoni O., Mannucci R., Nicoletti I., Corazzi L., et al. Human CD 1-restricted T cell recognition of lipids from pollens. J Exp Med 202 (2005) 295-308
64. Moody D.B., Ulrichs T., Muhlecker W., Young D.C., Gurcha S.S., Grant E., et al. CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. Nature 404 (2000) 884-888
65. Porcelli S., Brenner M.B., Greenstein J.L., Balk S.P., Terhorst C., and Bleicher P.A. Recognition of cluster of differentiation 1 antigens by human CD4-CD8-cytolyticT lymphocytes. Nature 341 (1989) 447-450
66. Faure F., Jitsukawa S., Miossec C., and Hercend T. CD1c as a target recognition structure for human T lymphocytes: analysis with peripheral blood gamma/delta cells. Eur J Immunol 20 (1990) 703-706
67. Spada F.M., Grant E.P., Peters P.J., Sugita M., Melian A., Leslie D.S., et al. Self-recognition of CD1 by gamma/delta T cells: implications for innate immunity. J Exp Med 191 (2000) 937-948
68. + T cells. Nature 372 (1994) 691-694
69. Gilleron M., Stenger S., Mazorra Z., Wittke F., Mariotti S., Bohmer G., et al. Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD 1-restricted T cells during infection with Mycobacterium tuberculosis. J Exp Med 199 (2004) 649-659
70. Matsunaga I., Bhatt A., Young D.C., Cheng T.Y., Eyles S.J., Besra G.S., et al. Mycobacterium tuberculosis pks12 produces a novel polyketide presented by CD1c to T cells. J Exp Med 200 (2004) 1559-1569
71. Moody D.B., Young D.C., Cheng T.Y., Rosat J.P., Roura-Mir C., O'Connor P.B., et al. T cell activation by lipopeptide antigens. Science 303 (2004) 527-531
72. Kawano T., Cui J., Koezuka Y., Toura I., Kaneko Y., Motoki K., et al. CD 1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides. Science 278 (1997) 1626-1629
73. Mattner J., DeBord K.L., Ismail N., Goff R.D., Cantu III C., Zhou D., et al. Both exogenous and endogenous glycolipid antigens activate N KT cells during microbial infections. Nature 434 (2005) 525-529
74. Kinjo Y., Wu D., Kim G., Xing G.-W., Poles M.A., Ho D.H., et al. Recognition of bacterial glycosphingolipids by natural killer T cells. Nature 434 (2005) 520-525
75. Kinjo Y., Tupin E., Wu D., Fujio M., Garcia-Navarro R., Benhnia M.R., et al. Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat Immunol 7 (2006) 978-986
76. Van Rhijn I., Young D.C., Im J.S., Levery S.B., Illarionov P.A., Besra G.S., et al. CD 1d-restricted T cell activation by non-lipidic small molecules. Proc Natl Acad Sci USA 101 (2004) 13578-13583