Mycobacterium tuberculosis subverts the differentiation of human monocytes into dendritic cells

European Journal of Immunology

Volumn 32, Issue 11, 2002, Pages 3050-3058

  Mariotti, Sabrina ^a   Teloni, Raffaela ^a   Iona, Elisabetta ^a   Fattorini, Lanfranco ^a   Giannoni, Federico ^a   Romagnoli, Guilia ^a   Orefici, Graziella ^a   Nisini, Roberto ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Antigen presenting cell; IL 4; Persistence; Phagocytosis; Tuberculosis

Indexed keywords

B7 ANTIGEN; CD1 ANTIGEN; CD83 ANTIGEN; CHEMOKINE RECEPTOR CCR7; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IMMUNE SYSTEM; INTRACELLULAR KILLING; LYMPHOCYTE PROLIFERATION; MONOCYTE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; T LYMPHOCYTE; UMBILICAL CORD BLOOD;

ANTIGEN PRESENTATION; ANTIGENS, CD1; CELL DIFFERENTIATION; DENDRITIC CELLS; HUMANS; IMMUNOPHENOTYPING; INTERFERON TYPE II; INTERLEUKIN-12; MONOCYTES; MYCOBACTERIUM TUBERCULOSIS;

EID: 0036858790     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200211)32:11<3050::AID-IMMU3050>3.0.CO;2-K     Document Type: Review

References (47)

1. Flynn, J. L. and Chan, J., Immunology of tuberculosis. Annu. Rev. Immunol. 2001. 19: 93-129.
2. Kaufmann, S. H. E., How can immunology contribute to the control of tuberculosis? Nat. Rev. Immunol. 2001. 1: 20-30.
3. Lauzardo, M. and Ashkin, D., Physiology at the dawn of the new century. Chest 2000. 117: 1455-1473.
4. Manabe, Y. C. and Bishai, W. R., Latent Mycobacterium tuberculosis-persistence, patience, and winning by waiting. Nat. Med. 2000. 6: 1327-1329.
5. Pulendran, B., Palucka, K. and Banchereau, J., Sensing pathogens and tuning immune responses. Science 2001. 293: 253-256.
6. Schluger, N. W. and Rom, W. N., The host immune response to tuberculosis. Am. J. Respir. Crit. Care Med. 1998. 157: 679-691.
7. Banchereau, J. and Steinman, R. M., Dendritic cells and the control of immunity. Nature 1998. 392: 245-252.
8. Hawiger, D., Inaba, K., Dorsett, Y., Guo, M., Mahnke, K., Rivera, M., Ravetch, J. V., Steinman, R. M. and Nussenzweig, M. C., Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J. Exp. Med. 2001. 194: 769-779.
9. Steinman, R. M., Turley, S., Mellman, I. and Inaba, K., The induction of tolerance by dendritic cells that have captured apoptotic cells. J. Exp. Med. 2000. 191: 411-416.
10. Lanzavecchia, A., From antigen presentation to T cell activation. Res. Immunol. 1998. 149: 626.
11. Mellman, I. and Steinman, R. M., Dendritic cells: specialized and regulated antigen processing machines. Cell 2001. 106: 255-258.
12. Cella, M., Sallusto, F. and Lanzavecchia, A., Origin, maturation and antigen presenting function of dendritic cells. Curr. Opin. Immunol. 1997. 9: 10-16.
13. Lanzavecchia, A., Dendritic cell maturation and generation of immune responses. Haematologica 1999. 84 Suppl EHA-4: 23-25.
14. Lanzavecchia, A. and Sallusto, F., Regulation of T cell immunity by dendritic cells. Cell 2001. 106: 263-266.
15. Lanzavecchia, A. and Sallusto, F., The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics. Curr. Opin. Immunol. 2001. 13: 291-298.
16. Lanzavecchia, A. and Sallusto, F., Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells. Science 2000. 290: 92-97.
17. Sadek, M. I., Sada, E., Toossi, Z., Schwander, S. K. and Rich, E. A., Chemokines induced by infection of mononuclear phagocytes with mycobacteria and present in lung alveoli during active pulmonary tuberculosis. Am. J. Respir. Cell. Mol. Biol. 1998. 19: 513-521.
18. Randolph, G. J., Inaba, K., Robbiani, D. F., Steinman, R. M. and Muller, W. A., Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity 1999. 11: 753-761.
19. Randolph, G. J., Beaulieu, S., Lebecque, S., Steinman, R. M. and Muller, W. A., Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking. Science 1998. 282: 480-483.
20. Giacomini, E., Iona, E., Ferroni, L., Miettinen, M., Fattorini, L., Orefici, G., Julkunen, I. and Coccia, E. M., Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response. J. Immunol. 2001. 166: 7033-7041.
21. Sallusto, F. and Lanzavecchia, A., Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 1994. 179: 1109-1118.
22. Van der Auwera, P., Interactions between antibiotics and phagocytosis in bacterial killing. Scand. J. Infect. Dis. Suppl. 1990. 74: 42-48.
23. van den Broek, P. J., Antimicrobial drugs, microorganisms, and phagocytes. Rev. Infect. Dis. 1989. 11: 213-245.
24. Fattorini, L., Xiao, Y., Li, B., Santoro, C., Ippoliti, F. and Orefici, G., Induction of IL-1 beta, IL-6, TNF-alpha, GM-CSF and G-CSF in human macrophages by smooth transparent and smooth opaque colonial variants of Mycobacterium avium. J. Med. Microbiol. 1994. 40: 129-133.
25. Fenhalls, G., Wong, A., Bezuidenhout, J., van Heiden, P., Bardin, P. and Lukey, P. T., In situ production of gamma interferon, interleukin-4, and tumor necrosis factor alpha mRNA in human lung tuberculous granulomas. Infect. Immun. 2000. 68: 2827-2836.
26. Baliko, Z., Szereday, L. and Szekeres-Bartho, J., Th2 biased immune response in cases with active Mycobacterium tuberculosis infection and tuberculin anergy. FEMS Immunol. Med. Microbiol. 1998. 22: 199-204.
27. Page, G., Lebecque, S. and Miossec, P., Anatomic localization of immature and mature dendritic cells in an ectopic lymphoid organ: correlation with selective chemokine expression in rheumatoid synovium. J. Immunol. 2002. 168: 5333-5341.
28. Caux, C., Vanbervliet, B., Massacrier, C., Ait-Yahia, S., Vaure, C., Chemin, K., Dieu Nosjean And, MC and Vicari, A., Regulation of dendritic cell recruitment by chemokines. Transplantation 2002. 73: S7-S11.
29. Parlato, S., Santini, S. M., Lapenta, C., Di Pucchio, T., Logozzi, M., Spada, M., Giammarioli, A. M., Malorni, W., Fais, S. and Belardelli, F., Expression of CCR-7, MIP-3beta, and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: importance for the rapid acquisition of potent migratory and functional activities. Blood 2001. 98: 3022-3029.
30. Randolph, G. J., Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators. Semin. Immunol. 2001. 13: 267-274.
31. Stenger, S., Hanson, D. A., Teitelbaum, R., Dewan, P., Niazi, K. R., Froelich, C. J., Ganz, T., Thoma-Uszynski, S., Melian, A., Bogdan, C., Porcelli, S. A., Bloom, B. R., Krensky, A. M. and Modlin, R. L., An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 1998. 282: 121-125.
32. Stenger, S., Mazzaccaro, R. J., Uyemura, K., Cho, S., Barnes, P. F., Rosat, J.-P., Sette, A., Brenner, M. B., Porcelli, S. A., Bloom, B. R. and Modlin, R. L., Differential effects of cytolytic T cell subsets on intracellular infection. Science 1997. 276: 1684-1687.
33. Johansson, U., Ivanyi, J. and Londei, M., Inhibition of IL-1 2 production in human dendritic cells matured in the presence of Bacillus Calmette-Guerin or lipoarabinomannan. Immunol. Lett. 2001. 77: 63-66.
34. Nigou, J., Zelle-Rieser, C., Gilleron, M., Thurnher, M. and Puzo, G., Mannosylated lipoarabinomannans inhibit IL-12 production by human dendritic cells: evidence for a negative signal delivered through the mannose receptor. J. Immunol. 2001. 166: 7477-7485.
35. Schaible, U. E., Hagens, K., Fischer, K., Collins, H. L. and Kaufmann, S. H., Intersection of group I CD1 molecules and mycobacteria in different intracellular compartments of dendritic cells. J. Immunol. 2000. 164: 4843-4852.
36. Giuliani, A., Prete, S. P., Graziani, G., Aquino, A., Balduzzi, A., Sugita, M., Brenner, M. B., Iona, E., Fattorini, L., Orefici, G., Porcelli, S. A. and Bonmassar, E., Influence of Mycobacterium bovis bacillus Calmette Guerin on in vitro induction of CD1 molecules in human adherent mononuclear cells. Infect. Immun. 2001. 69: 7461-7470.
37. Stenger, S., Niazi, K. R. and Modlin, R. L., Down-regulation of CD1 on antigen-presenting cells by infection with Mycobacterium tuberculosis. J. Immunol. 1998. 161: 3582-3588.
38. Albert, M. L., Jegathesan, M. and Darnell, R. B., Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells. Nat. Immunol. 2001. 2: 1010-1017.
39. Kalinski, P., Hilkens, C. M., Wierenga, E. A. and Kapsenberg, M. L., T cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunol. Today 1999. 20: 561-567.
40. Ding, A. H., Nathan, C. F. and Stuehr, D. J., Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 1988. 141: 2407-2412.
41. Flynn, J. L., Chan, J., Triebold, K. J., Dalton, D. K., Stewart, T. A. and Bloom, B. R., An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 1993. 178: 2249-2254.
42. Dalton, D. K., Pitts-Meek, S., Keshav, S., Figari, I. S., Bradley, A. and Stewart, T. A., Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science 1993. 259: 1739-1742.
43. Pathan, A. A., Wilkinson, K. A., Klenerman, P., McShane, H., Davidson, R. N., Pasvol, G., Hill, A. V. and Lalvani, A., Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment. J. Immunol. 2001. 167: 5217-5225.
44. Nisini, R., Paroli, M., Accapezzato, D., Bonino, F., Rosina, F., Santantonio, T., Sallusto, F., Amoroso, A., Houghton, M. and Barnaba, V., Human CD4+ T cell response to hepatitis delta virus: identification of multiple epitopes; and characterization of T-helper cytokine profiles. J. Virol. 1997. 71: 2241-2251.
45. Accapezzato, D., Nisini, R., Paroli, M., Bruno, G., Bonino, F., Houghton, M. and Barnaba, V., Generation of an MHC class II-restricted T cell epitope by extracellular processing of hepatitis delta antigen. J. Immunol. 1998. 160: 5262-5266.
46. Nisini, R., Fattorossi, A., Ferlini, C. and D'Amelio, R., One cause for the apparent inability of human T cell clones to function as professional superantigen-presenting cells is autoactivation. Eur. J. Immunol. 1996. 26: 797-803.
47. Fattorossi, A., Nisini, R., Pizzolo, J. G. and D'Amelio, R., New, simple flow cytometry technique to discriminate between internalized and membrane-bound particles in phagocytosis. Cytometry 1989. 10: 320-325.