Regulation of CD1d expression and function by a herpesvirus infection

Journal of Clinical Investigation

Volumn 115, Issue 5, 2005, Pages 1369-1378

  Sanchez, David Jesse ^a   Gumperz, Jenny E ^b   Ganem, Don ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD1D ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN MIR1; PROTEIN MIR2; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ANTIGEN RECOGNITION; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DEGRADATION; DOWN REGULATION; ENDOCYTOSIS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HERPES VIRUS INFECTION; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; IMMUNE RESPONSE; IMMUNOMODULATION; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; UBIQUITINATION; VIRUS REPLICATION;

ANTIGENS, CD1; DOWN-REGULATION; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 8, HUMAN; HUMANS; UBIQUITIN; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 18244402636     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200524041     Document Type: Article

References (57)

1. Katze, M.G., He, Y., and Gale, M., Jr. 2002. Viruses and interferon: a fight for supremacy. Nat. Rev. Immunol. 2:675-687.
2. French, A.R., and Yokoyama, W.M. 2003. Natural killer cells and viral infections. Curr. Opin. Immunol. 15:45-51.
3. Gumperz, J.E., and Brenner, M.B. 2001. CD1-specific T cells in microbial immunity. Curr. Opin. Immunol. 13:471-478.
4. Porcelli, S.A., and Modlin, R.L. 1999. The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids. Annu. Rev. Immunol. 17:297-329.
5. Beckman, E.M., et al. 1996. CD1c restricts responses of mycobacteria-specific T cells. Evidence for antigen presentation by a second member of the human CD1 family. J. Immunol. 157:2795-2803.
6. Beckman, E.M., et al. 1994. Recognition of a lipid antigen by CD1-restricted alpha beta+ T cells. Nature. 372:691-694.
7. Moody, D.B., et al. 1997. Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells. Science. 278:283-286.
8. Sieling, P.A., et al. 1995. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science. 269:227-230.
9. Brigl, M., Bry, L., Kent, S.C., Gumperz, J.E., and Brenner, M.B. 2003. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat. Immunol. 4:1230-1237.
10. Gumperz, J.E., et al. 2000. Murine CD1d-restricted T cell recognition of cellular lipids. Immunity. 12:211-221.
11. Bendelac, A., Rivera, M.N., Park, S.H., and Roark, J.H. 1997. Mouse CD1-spedfic NK1 T cells: development, specificity, and function. Annu. Rev. Immunol. 15:535-562.
12. Behar, S.M., and Cardell, S. 2000. Diverse CD1d-restricred T cells: diverse phenotypes, and diverse functions. Semin. Immunol. 12:551-560.
13. Kawano, T., et al. 1997. CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science. 278:1626-1629.
14. Baron, J.L., et al. 2002. Activation of a nonclassical NKT cell subset in a transgenic mouse model of hepatitis B virus infection. Immunity. 16:583-594.
15. Johnson, T.R., Hong, S., Van Kaer, L., Koezuka, Y., and Graham, B.S. 2002. NK T cells contribute to expansion of CD8(+) T cells and amplification of antiviral immune responses to respiratory syncytial virus. J. Virol 76:4294-4303.
16. Grubor-Bauk, B., Simmons, A., Mayrhofer, G., and Speck, P.G. 2003. Impaired clearance of herpes simplex virus type 1 ftom mice lacking CD1d or NKT cells expressing the semivariant V alpha 14-J alpha 281 TCR. J. Immunol. 170:1430-1434.
17. Roberts, T.J., Lin, Y.; Spence, P.M., Van Kaer, L., and Brutkiewicz, R.R. 2004. CD1d1-dependent control of the magnitude of an acute antiviral immune response. J. Immunol. 172:3454-3461.
18. Ploegh, H.L. 1998. Viral strategies of immune evasion. Science. 280:248-253.
19. Yewdell, J.W., and Hill, A.B. 2002. Viral interference with antigen presentation. Nat. Immunol. 3:1019-1025.
20. Chatterjee, M., Osborne, J., Bestetti, G., Chang, Y., and Moore, P.S. 2002. Viral IL-6-induced cell proliferation and immune evasion of interferon activity. Science. 298:1432-1435.
21. Zhu, F.X., King, S.M., Smith, E.J., Levy, D.E., and Yuan, Y. 2002. A Kaposi's sarcoma-associated herpesviral protein inhibits virus-mediated induction of type I interferon by blocking IRF-7 phosphorylation and nuclear accumulation. Proc. Natl. Acad. Sci. U. S. A. 99:5573-5578.
22. Eidson, K.M., Hobbs, W.E., Manning, B.J., Carlson, P., and DeLuca, N.A. 2002. Expression of herpes simplex virus ICPO inhibits the induction of interferon-stimulated genes by viral infection. J. Virol. 76:2180-2191.
23. He, B., Gross, M., and Roizman, B. 1997. The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. Proc. Natl. Acad. Sci. U. S. A. 94:843-848.
24. Lodoen, M., et al. 2003. NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules. J. Exp. Med. 197:1245-1253.
25. Ganem, D. 1997. KSHV and Kaposi's sarcoma: the end of the beginning? Cell. 91:157-160.
26. Dourmishev, L.A., Dourmishev, A.L., Palmeri, D., Schwartz, R.A., and Lukac, D.M. 2003. Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) epidemiology and pathogenesis. Microbiol. Mol. Biol. Rev. 67:175-212.
27. Hengge, U.R., et al. 2002. Update on Kaposi's sarcoma and other HHV8 associated diseases. Part 2: pathogenesis, Castleman's disease, and pleural effusion lymphoma. Lancet. Infect. Dis. 2:344-352.
28. Coscoy, L., and Ganem, D. 2000. Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis. Proc. Natl. Acad. Sci. U. S. A. 97:8051-8056.
29. Haque, M., et al. 2001. Major histocompatibility complex class I molecules are down-regulated at the cell surface by the K5 protein encoded by Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8. J. Gen. Virol. 82:1175-1180.
30. Ishido, S., Wang, C., Lee, B.S., Cohen, G.B., and Jung, J.U. 2000. Downregulation of major histocompatibility complex class I molecules by Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins. J. Virol. 74:5300-5309.
31. Stevenson, P.G., Efstathiou, S., Doherry, P.C., and Lehner, P.J. 2000. Inhibition of MHC class I-restricted antigen presentation by gamma 2-herpesviruses. Proc. Natl. Acad. Sci. U. S. A. 97:8455-8460.
32. Coscoy, L., Sanchez, D.J., and Ganem, D. 2001. A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition. J. Cell Biol. 155:1265-1273.
33. Coscoy, L., and Ganem, D. 2001. A viral protein that selectively downregulates ICAM-1 and B7-2 and modulates T cell costimulation. J. Clin. Invest. 107:1599-1606.
34. Ishido, S., et al. 2000. Inhibition of natural killer cell-mediated cytotoxicity by Kaposi's sarcoma-associated herpesvirus K5 protein. Immunity. 13:365-374.
35. Chang, J., Renne, R., Dittmer, D., and Ganem, D. 2000. Inflammatory cytokines and the reactivation of Kaposi's sarcoma-associated herpesvirus lyric replication. Virology. 266:17-25.
36. Sanchez, D.J., Coscoy, L., and Ganem, D. 2002. Functional organization of M1R2, a novel viral regulator of selective endocytosis. J. Biol. Chem. 277:6124-6130.
37. Kang, S.J., and Cresswell, P. 2002. Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules. EMBO J. 21:1650-1660.
38. Boname, J.M., and Stevenson, P.G. 2001. MHC class I ubiquitination by a viral PHD/LAP finger protein. Immunity. 15:627-636.
39. Hewitt, E.W., et al. 2002. Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation. EMBO J. 21:2418-2429.
40. Katzmann, D.J., Odorizzi, G., and Emr, S.D. 2002. Receptor downregulation and multivesicular-body sorting. Nat. Rev. Mol. Cell Biol. 3:893-905.
41. Herskovits, J.S., Burgess, C.C., Obar, R.A., and Vallee, R.B. 1993. Effects of mutant rat dynamin on endocytosis. J. Cell Biol. 122:565-578.
42. Tomescu, C., Law, W.K., and Kedes, D.H. 2003. Surface downregulation of major histocompatibility complex class I, PE-CAM, and ICAM-1 following de novo infection of endothelial cells with Kaposi's sarcoma-associated herpesvirus. J. Virol. 77:9669-9684.
43. Krmpotic, A., et al. 2002. MCMV glycoprotein gp40 confers virus resistance to CD8+ T cells and NK cells in vivo. Nat. Immunol. 3:529-535.
44. Nishimura, T., et al. 2000. The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes. Int. Immunol. 12:987-994.
45. Carnaud, C., et al. 1999. Cutting edge: Crosstalk between cells of the innate immune system: NKT cells rapidly activate NK cells. J. Immunol. 163:4647-4650.
46. Chiu, N.M., Chun, T., Fay, M., Mandai, M., and Wang, C.R. 1999. The majority of H2-M3 is retained intracellularly in a pepride-receptive state and traffics to the cell surface in the presence of N-formylated peptides. J. Exp.Med. 190:423-434.
47. Sriram, V., et al. 2002. Inhibition of glycolipid shedding rescues recognition of a CD1+ T cell lymphoma by natural killer T (NKT) cells. Proc. Natl. Acad. Sci. U. S. A. 99:8197-8202.
48. Castano, A.R., et al. 1995. Peptide binding and presentation by mouse CD1. Science. 269:223-226.
49. Sugita, M., et al. 2002. Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells. Immunity 16:697-706.
50. Elewaut, D., et al. 2003. The adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Valpha14i NKT cells. J. Exp. Med. 198:1133-1146.
51. Cernadas, M., et al. 2003. Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development. J. Immunol. 171:4149-4155.
52. Chiu, Y.H., et al. 1999. Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments. J. Exp. Med. 189:103-110.
53. Roberts, T.J., et al. 2002. Recycling CD1d1 molecules present endogenous antigens processed in an endocytic compartment to NKT cells. J Immunol. 168:5409-5414.
54. Prigozy, T.I., et al. 2001. Glycolipid antigen processing for presentation by CD1d molecules. Science. 291:664-667.
55. Zhou, D., et al. 2004. Editing of Cd1d-bound lipid antigens by endosomal lipid transfer proteins. Science. 303:523-527.
56. Jayawardena-Wolf, J., Benlagha, K., Chiu, Y.H., Mehr, R., and Bendelac, A. 2001. CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain. Immunity. 15:897-908.
57. Gumperz, J.E., Miyake, S., Yamamura, T., and Brenner, M.B. 2002. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J. Exp. Med. 195:625-636.