Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b

EMBO Journal

Volumn 25, Issue 15, 2006, Pages 3684-3692

  Garcia Alles, Luis F ^a   Versluis, Kees ^b   Maveyraud, Laurent ^a   Vallina, Ana Tesouro ^a   Sansano, Sebastiano ^c   Bello, Nana Fatimath ^a   Gober, Hans Jürgen ^c   Guillet, Valérie ^a   De La Salle, Henri ^d,e,f   Puzo, Germain ^a   Mori, Lucia ^c   Heck, Albert J R ^b   De Libero, Gennaro ^c   Mourey, Lionel ^a  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY HOSPITAL BASEL   (Switzerland)

^d INSERM   (France)

^e UNIVERSITÉ DE STRASBOURG   (France)

^f ETABLISSEMENT FRANÇAIS DU SANG   (France)

Author keywords

Antigen; CD1 proteins; Crystal structure; Endogenous lipid; Mass spectrometry

Indexed keywords

CD1 ANTIGEN; CD1B ANTIGEN; LIPID; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; ENDOPLASMIC RETICULUM; ENDOSOME; HYDROPHOBICITY; ISOELECTRIC FOCUSING; LIGAND BINDING; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; T LYMPHOCYTE;

ANTIGENS, CD1; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROPHOBICITY; ISOELECTRIC FOCUSING; LIGANDS; MASS SPECTROMETRY; MODELS, MOLECULAR; PHOSPHATIDYLCHOLINES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING;

EID: 33747621666     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601244     Document Type: Article

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