Cholesterol Depletion Disrupts Caveolae and Insulin Receptor Signaling for Metabolic Control via Insulin Receptor Substrate-1, but Not for Mitogen-activated Protein Kinase Control

Journal of Biological Chemistry

Volumn 276, Issue 13, 2001, Pages 9670-9678

  Parpal, Santiago ^a   Karlsson, Margareta ^a   Thorn, Hans ^a   Strålfors, Peter ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; ENZYMES; GLUCOSE; INSULIN;

MITOGENIC EFFECTS;

CHOLESTEROL;

BETA CYCLODEXTRIN; CHOLESTEROL; GLUCOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; IODINE 125; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; PROTEIN SHC; BETA CYCLODEXTRIN DERIVATIVE; CARCINOGEN; CYCLODEXTRIN; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 3; ONCOPROTEIN; PHOSPHOPROTEIN; PROTEIN; PROTEIN SERINE THREONINE KINASE; SERINE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SRC HOMOLOGY 2 DOMAIN CONTAINING, TRANSFORMING PROTEIN 1; SRC HOMOLOGY 2 DOMAIN-CONTAINING, TRANSFORMING PROTEIN 1; THREONINE; TYROSINE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ADIPOCYTE; ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CAVEOLA; CELL MEMBRANE; CONTROLLED STUDY; GLUCOSE TRANSPORT; IMMUNOBLOTTING; INSULIN BINDING; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN TREATMENT; METABOLIC REGULATION; MITOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION; TARGET CELL; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CELL DIVISION; CELL STRAIN 3T3; DOSE RESPONSE; DRUG EFFECT; ELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; METABOLISM; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; RABBIT; SPRAGUE DAWLEY RAT; TIME;

ANIMALIA; BACTERIA (MICROORGANISMS); BOS TAURUS; BOVIDAE; BOVINAE; LACTOBACILLUS; MYXOZOA; PROTOZOA; SUS SCROFA; TETRAHYMENA;

3T3 CELLS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ADIPOCYTES; ANIMALS; BETA-CYCLODEXTRINS; CARCINOGENS; CAVEOLAE; CELL DIFFERENTIATION; CELL DIVISION; CELL MEMBRANE; CELLS, CULTURED; CHOLESTEROL; CYCLODEXTRINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLUCOSE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INSULIN; MAP KINASE SIGNALING SYSTEM; MICE; MICROSCOPY, ELECTRON; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, INSULIN; SERINE; SIGNAL TRANSDUCTION; THREONINE; TIME FACTORS; TYROSINE;

EID: 0035971086     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M007454200     Document Type: Article

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