QSAR using evolved neural networks for the inhibition of mutant PfDHFR by pyrimethamine derivatives

BioSystems

Volumn 92, Issue 1, 2008, Pages 10-15

  Hecht, David ^a   Cheung, Mars ^b   Fogel, Gary B ^b  

^a Southwestern College   (United States)

^b NATURAL SELECTION INC   (United States)

Author keywords

Dihydrofolate reductase; Evolutionary computation; Malaria; Neural networks; QSAR

Indexed keywords

DIHYDROFOLATE REDUCTASE; PYRIMETHAMINE;

ARTIFICIAL NEURAL NETWORK; DRUG; MALARIA;

ARTICLE; ARTIFICIAL NEURAL NETWORK; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; MALARIA; NONLINEAR SYSTEM; PHYSICAL CHEMISTRY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATISTICAL MODEL;

EID: 39949084319     PISSN: 03032647     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biosystems.2007.10.005     Document Type: Article

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