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Volumn 65, Issue 1, 2002, Pages 37-47

Quantitative structure-activity relationships by evolved neural networks for the inhibition of dihydrofolate reductase by pyrimidines

Author keywords

Artificial neural networks; Dihydrofolate reductase; Evolutionary computation; Quantitative structure activity relationships

Indexed keywords

DIHYDROFOLATE REDUCTASE; PYRIMIDINE DERIVATIVE;

EID: 0036120914     PISSN: 03032647     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-2647(01)00192-7     Document Type: Article
Times cited : (15)

References (29)
  • 2
    • 0026075594 scopus 로고
    • Applications of neural networks in quantitative structure-activity relationships of dihydrofolate reductase inhibitors
    • (1991) J. Med. Chem. , vol.34 , Issue.9 , pp. 2824-2836
    • Andrea, T.A.1    Kalayeh, H.2
  • 15
    • 0028548591 scopus 로고
    • Evolutionary programming applied to the development of quantitative structure-activity relationships and quantitative structure-property relationships
    • (1994) J. Chem. Inf. Comput. Sci. , vol.34 , pp. 1279-1287
    • Luke, B.T.1
  • 22
    • 0029970338 scopus 로고    scopus 로고
    • Evolutionary optimization in quantitative structure-activity relationship: An application of genetic neural networks
    • (1996) J. Med. Chem. , vol.39 , pp. 1521-1530
    • So, S.-S.1    Karplus, M.2
  • 24
    • 0031434910 scopus 로고    scopus 로고
    • Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 1. Method and validations
    • (1997) J. Med. Chem. , vol.40 , pp. 4347-4359
    • So, S.-S.1    Karplus, M.2
  • 25
    • 0031466773 scopus 로고    scopus 로고
    • Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications
    • (1997) J. Med. Chem. , vol.40 , pp. 4360-4371
    • So, S.-S.1    Karplus, M.2
  • 26
    • 0026738394 scopus 로고
    • Application of neural networks: Quantitative structure-activity relationships of the derivatives of 2,4-diamino-5-(substituted-benzyl)pyrimidines as DHFR inhibitors
    • (1992) J. Med. Chem. , vol.35 , pp. 3201-3207
    • So, S.-S.1    Richards, W.G.2
  • 29
    • 84985315770 scopus 로고
    • Experiments on whether schooling by their prey affects the hunting behavior of cephalopods and fish predators
    • (1974) J. Zool. Lond. , vol.172 , pp. 549-569
    • Neill, S.R.St.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.