Evaluating the high-throughput screening computations

Journal of Biomolecular Screening

Volumn 10, Issue 7, 2005, Pages 649-652

  Lang, Paula Therese ^a   Kuntz, Irwin D ^a,d   Maggiora, Gerald M ^b   Bajorath, Jürgen ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c UNIVERSITY OF BONN   (Germany)

^d Genentech Hall N474A ^*  (United States)

Author keywords

DHFR; Docking; High throughput screening; Judges' review; QSAR MS

Indexed keywords

DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE INHIBITOR; DIHYDROFOLIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TETRAHYDROFOLIC ACID;

CHEMICAL ANALYSIS; COMPETITION; COMPETITIVE INHIBITION; ENZYME ACTIVITY; EVALUATION; EXPERIMENTAL DESIGN; HIGH THROUGHPUT SCREENING; HUMAN; MATHEMATICAL ANALYSIS; NONHUMAN; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; SCORING SYSTEM;

COMPUTATIONAL BIOLOGY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FOLIC ACID ANTAGONISTS; MODELS, CHEMICAL; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 26944477332     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057105281269     Document Type: Review

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