Prediction of drug solubility from structure

Advanced Drug Delivery Reviews

Volumn 54, Issue 3, 2002, Pages 355-366

  Jorgensen, William L ^a   Duffy, Erin M ^b  

^a YALE UNIVERSITY   (United States)

^b Rib X Pharmaceuticals Incorporated   (United States)

Author keywords

Aqueous solubility; Drug design; Drug solubility; Molecular properties; Quantitative structure properties relationships (QSPR)

Indexed keywords

SOLUBILITY;

BIOAVAILABILITY;

DRUG DOSAGE;

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHANE; 1,2,4 TRIBROMOBENZENE; 3 METHYL 3 HEXANOL; 3,3 DIMETHYL 1 BUTANOL; 4 METHYLMORPHOLINE; 7,12 DIMETHYLBENZ[A]ANTHRACENE; ACICLOVIR; ALCOHOL DERIVATIVE; BENFLURALIN; BENZENE DERIVATIVE; BENZO[J]FLUORANTHENE; BIS(2 CHLOROETHYL)SULFONE; FLUORANTHENE; HALOPERIDOL; HEPTABARB; ISONIAZID; LUPETAZINE; MINOXIDIL; MORPHOLINE DERIVATIVE; OMEPRAZOLE; PIPERAZINE DERIVATIVE; POLYCHLORINATED BIPHENYL DERIVATIVE; SULFADIAZINE; SULFONE DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; COMBINATORIAL LIBRARY; DATA BASE; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG SCREENING; DRUG SOLUBILITY; DRUG STRUCTURE; MATHEMATICAL ANALYSIS; PREDICTION; PRIORITY JOURNAL; QUALITY CONTROL; REVIEW;

EID: 0037204544     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(02)00008-X     Document Type: Article

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