-
2
-
-
0021741559
-
Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells
-
Ashcroft FM, Harrison DE, Ashcroft SJ: Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells. Nature 1984;312:446-448.
-
(1984)
Nature
, vol.312
, pp. 446-448
-
-
Ashcroft, F.M.1
Harrison, D.E.2
Ashcroft, S.J.3
-
3
-
-
0026712462
-
+ channels and their probable role for the membrane potential of mouse motor nerve endings
-
+ channels and their probable role for the membrane potential of mouse motor nerve endings. Pflügers Arch 1992;421:292-294
-
(1992)
Pflügers Arch
, vol.421
, pp. 292-294
-
-
Deist, M.1
Repp, H.2
Dreyer, F.3
-
4
-
-
0035947177
-
Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure
-
Yamada K, Ji JJ, Yuan H, Miki T, Sato S, Horimoto N, Shimizu T, Seino S, Inagaki N: Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science 2001;292:1543-1546.
-
(2001)
Science
, vol.292
, pp. 1543-1546
-
-
Yamada, K.1
Ji, J.J.2
Yuan, H.3
Miki, T.4
Sato, S.5
Horimoto, N.6
Shimizu, T.7
Seino, S.8
Inagaki, N.9
-
5
-
-
0025064919
-
Action potential duration and activation of ATP-sensitive potassium current in isolated guinea pig ventricular myocytes
-
Faivre JF, Findlay I: Action potential duration and activation of ATP-sensitive potassium current in isolated guinea pig ventricular myocytes. Biochim Biophys Acta 1990;1029:167-172.
-
(1990)
Biochim Biophys Acta
, vol.1029
, pp. 167-172
-
-
Faivre, J.F.1
Findlay, I.2
-
7
-
-
0030755672
-
+ channel openers and glucose deprivation
-
+ channel openers and glucose deprivation. J Physiol 1997;502:397-408.
-
(1997)
J Physiol
, vol.502
, pp. 397-408
-
-
Langheinrich, U.1
Daut, J.2
-
8
-
-
0030772859
-
ATP-sensitive and inwardly rectifying potassium channels in smooth muscle
-
Quayle JM, Nelson MT, Standen NB: ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. Physiol Rev 1997;77:1165-1232.
-
(1997)
Physiol Rev
, vol.77
, pp. 1165-1232
-
-
Quayle, J.M.1
Nelson, M.T.2
Standen, N.B.3
-
9
-
-
0028972501
-
ATP: An inward rectifier subunit plus the sulfonylurea receptor
-
ATP: an inward rectifier subunit plus the sulfonylurea receptor. Science 1995;270:1166-1170.
-
(1995)
Science
, vol.270
, pp. 1166-1170
-
-
Inagaki, N.1
Gonoi, T.2
Clement, J.P.3
Namba, N.4
Inazawa, J.5
Gonzalez, G.6
Aguilar-Bryan, L.7
Seino, S.8
Bryan, J.9
-
13
-
-
0032505868
-
ATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit
-
ATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit. Proc Natl Acad Sci USA 1998;95:13953-13958.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13953-13958
-
-
Drain, P.1
Li, L.2
Wang, J.3
-
15
-
-
0032491319
-
ATP channels
-
ATP channels. Science 1998;282:1141-1144.
-
(1998)
Science
, vol.282
, pp. 1141-1144
-
-
Baukrowitz, T.1
Schulte, U.2
Oliver, D.3
Herlitze, S.4
Krauter, T.5
Tucker, S.J.6
Ruppersberg, J.P.7
Fakler, B.8
-
16
-
-
0032500529
-
Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA
-
Gribble FM, Proks P, Corkey BE, Ashcroft FM: Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA. J Biol Chem 1998;273:26383-26387.
-
(1998)
J Biol Chem
, vol.273
, pp. 26383-26387
-
-
Gribble, F.M.1
Proks, P.2
Corkey, B.E.3
Ashcroft, F.M.4
-
17
-
-
0032553536
-
Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel
-
Branstrom R, Leibiger IB, Leibiger B, Corkey BE, Berggren PO, Larsson O: Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel. J Biol Chem 1998;273:31395-31400.
-
(1998)
J Biol Chem
, vol.273
, pp. 31395-31400
-
-
Branstrom, R.1
Leibiger, I.B.2
Leibiger, B.3
Corkey, B.E.4
Berggren, P.O.5
Larsson, O.6
-
18
-
-
0030016913
-
Adenosine diphosphate as an intracellular regulator of insulin secretion
-
Nichols CG, Shyng SL, Nestorowicz A, Glaser B, Clement JP, Gonzalez G, Aguilar-Bryan L, Permutt MA, Bryan J: Adenosine diphosphate as an intracellular regulator of insulin secretion. Science 1996;272:1785-1787.
-
(1996)
Science
, vol.272
, pp. 1785-1787
-
-
Nichols, C.G.1
Shyng, S.L.2
Nestorowicz, A.3
Glaser, B.4
Clement, J.P.5
Gonzalez, G.6
Aguilar-Bryan, L.7
Permutt, M.A.8
Bryan, J.9
-
20
-
-
0030609142
-
ATP channel activity by diazoxide and MgADP: Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor
-
ATP channel activity by diazoxide and MgADP: distinct functions of the two nucleotide binding folds of the sulfonylurea receptor. J Gen Physiol 1997;110:643-654.
-
(1997)
J Gen Physiol
, vol.110
, pp. 643-654
-
-
Shyng, S.1
Ferrigni, T.2
Nichols, C.G.3
-
22
-
-
0033558137
-
ATP channels in dopaminergic midbrain neurons
-
ATP channels in dopaminergic midbrain neurons. EMBO J 1999;18:833-846.
-
(1999)
EMBO J
, vol.18
, pp. 833-846
-
-
Liss, B.1
Bruns, R.2
Roeper, J.3
-
23
-
-
0029743412
-
+ channel
-
+ channel. J Biol Chem 1996;271:24321-24324.
-
(1996)
J Biol Chem
, vol.271
, pp. 24321-24324
-
-
Isomoto, S.1
Kondo, C.2
Yamada, M.3
Matsumoto, S.4
Higashiguchi, O.5
Horio, Y.6
Matsuzawa, Y.7
Kurachi, Y.8
-
24
-
-
20044367632
-
ATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature
-
ATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature. BMC Physiol 2005;5:1.
-
(2005)
BMC Physiol
, vol.5
, pp. 1
-
-
Morrissey, A.1
Rosner, E.2
Lanning, J.3
Parachuru, L.4
Dhar Chowdhury, P.5
Han, S.6
Lopez, G.7
Tong, X.8
Yoshida, H.9
Nakamura, T.Y.10
Artman, M.11
Giblin, J.P.12
Tinker, A.13
Coetzee, W.A.14
-
25
-
-
0029024314
-
Cloning of the beta cell high-affinity sulfonylurea receptor: A regulator of insulin secretion
-
Aguilar-Bryan L, Nichols CG, Wechsler SW, Clement JP, Boyd AE 3rd, Gonzalez G, Herrera-Sosa H, Nguy K, Bryan J, Nelson DA: Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. Science 1995;268:423-426.
-
(1995)
Science
, vol.268
, pp. 423-426
-
-
Aguilar-Bryan, L.1
Nichols, C.G.2
Wechsler, S.W.3
Clement, J.P.4
Boyd 3rd, A.E.5
Gonzalez, G.6
Herrera-Sosa, H.7
Nguy, K.8
Bryan, J.9
Nelson, D.A.10
-
26
-
-
20644449030
-
Function and distribution of the SUR isoforms and splice variants
-
Shi NQ, Ye B, Makielski JC: Function and distribution of the SUR isoforms and splice variants. J Mol Cell Cardiol 2005;39:51-60.
-
(2005)
J Mol Cell Cardiol
, vol.39
, pp. 51-60
-
-
Shi, N.Q.1
Ye, B.2
Makielski, J.C.3
-
28
-
-
0033783059
-
Sulfonylurea sensitivity of adenosine triphosphate-sensitive potassium channels from beta cells and extrapancreatic tissues
-
Gribble FM, Ashcroft FM: Sulfonylurea sensitivity of adenosine triphosphate-sensitive potassium channels from beta cells and extrapancreatic tissues. Metabolism 2000;49:3-6.
-
(2000)
Metabolism
, vol.49
, pp. 3-6
-
-
Gribble, F.M.1
Ashcroft, F.M.2
-
30
-
-
0042071600
-
Sulphonylurea action revisited: The post-cloning era
-
Gribble FM, Reimann F: Sulphonylurea action revisited: the post-cloning era. Diabetologia 2003;46:875-891.
-
(2003)
Diabetologia
, vol.46
, pp. 875-891
-
-
Gribble, F.M.1
Reimann, F.2
-
31
-
-
0027409532
-
The pharmacology of ATP-sensitive potassium channels
-
Edwards G, Weston AH: The pharmacology of ATP-sensitive potassium channels. Annu Rev Pharmacol Toxicol 1993;33:597-637.
-
(1993)
Annu Rev Pharmacol Toxicol
, vol.33
, pp. 597-637
-
-
Edwards, G.1
Weston, A.H.2
-
32
-
-
0026498034
-
Potassium channel openers: Pharmacological and clinical aspects
-
Quast U: Potassium channel openers: pharmacological and clinical aspects. Fundam Clin Pharmacol 1992;6:279-293.
-
(1992)
Fundam Clin Pharmacol
, vol.6
, pp. 279-293
-
-
Quast, U.1
-
33
-
-
1842579441
-
Type 2 diabetes mellitus: Not quite exciting enough?
-
Ashcroft F, Rorsman P: Type 2 diabetes mellitus: not quite exciting enough? Hum Mol Genet 2004;1:21-31.
-
(2004)
Hum Mol Genet
, vol.1
, pp. 21-31
-
-
Ashcroft, F.1
Rorsman, P.2
-
34
-
-
0029243704
-
An imprinted gene(s) for diabetes?
-
Temple IK, James RS, Crolla JA, Sitch FL, Jacobs PA, Howell WM, Betts P, Baum JD, Shield JP: An imprinted gene(s) for diabetes? Nat Genet 1995;9:110-112.
-
(1995)
Nat Genet
, vol.9
, pp. 110-112
-
-
Temple, I.K.1
James, R.S.2
Crolla, J.A.3
Sitch, F.L.4
Jacobs, P.A.5
Howell, W.M.6
Betts, P.7
Baum, J.D.8
Shield, J.P.9
-
35
-
-
20244368494
-
Relapsing diabetes can result from moderately activating mutations in KCNJ11
-
Gloyn AL, Reimann F, Girard C, Edghill EL, Proks P, Pearson ER, Temple IK, Mackay DJ, Shield JP, Freedenberg D, Noyes K, Ellard S, Ashcroft FM, Gribble FM, Hattersley AT: Relapsing diabetes can result from moderately activating mutations in KCNJ11. Hum Mol Genet 2005;14:925-934.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 925-934
-
-
Gloyn, A.L.1
Reimann, F.2
Girard, C.3
Edghill, E.L.4
Proks, P.5
Pearson, E.R.6
Temple, I.K.7
Mackay, D.J.8
Shield, J.P.9
Freedenberg, D.10
Noyes, K.11
Ellard, S.12
Ashcroft, F.M.13
Gribble, F.M.14
Hattersley, A.T.15
-
36
-
-
0342902204
-
Neonatal diabetes mellitus due to complete glucokinase deficiency
-
Njolstad PR, Sovik O, Cuesta-Munoz A, Bjorkhaug L, Massa O, Barbetti F, Undlien DE, Shiota C, Magnuson MA, Molven A, Matschinsky FM, Bell GI: Neonatal diabetes mellitus due to complete glucokinase deficiency. N Engl J Med 2001;344:1588-1592.
-
(2001)
N Engl J Med
, vol.344
, pp. 1588-1592
-
-
Njolstad, P.R.1
Sovik, O.2
Cuesta-Munoz, A.3
Bjorkhaug, L.4
Massa, O.5
Barbetti, F.6
Undlien, D.E.7
Shiota, C.8
Magnuson, M.A.9
Molven, A.10
Matschinsky, F.M.11
Bell, G.I.12
-
37
-
-
0031031571
-
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
-
Stoffers DA, Zinkin NT, Stanojevic V, Clarke WL, Habener JF: Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat Genet 1997;15:106-110.
-
(1997)
Nat Genet
, vol.15
, pp. 106-110
-
-
Stoffers, D.A.1
Zinkin, N.T.2
Stanojevic, V.3
Clarke, W.L.4
Habener, J.F.5
-
38
-
-
0141787919
-
Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1
-
Schwitzgebel VM, Mamin A, Brun T, Ritz-Laser B, Zaiko M, Maret A, Jornayvaz FR, Theintz GE, Michielin O, Melloul D, Philippe J: Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1. J Clin Endocrinol Metab 2003;88:4398-4406.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 4398-4406
-
-
Schwitzgebel, V.M.1
Mamin, A.2
Brun, T.3
Ritz-Laser, B.4
Zaiko, M.5
Maret, A.6
Jornayvaz, F.R.7
Theintz, G.E.8
Michielin, O.9
Melloul, D.10
Philippe, J.11
-
39
-
-
0029058637
-
Neonatal diabetes mellitus associated with severe diarrhea, hyperimmunoglobulin E syndrome, and absence of islets of Langerhans
-
Roberts J, Searle J: Neonatal diabetes mellitus associated with severe diarrhea, hyperimmunoglobulin E syndrome, and absence of islets of Langerhans. Pediatr Pathol Lab Med 1995;15:477-483.
-
(1995)
Pediatr Pathol Lab Med
, vol.15
, pp. 477-483
-
-
Roberts, J.1
Searle, J.2
-
40
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson J, Carlsson L, Edlund T, Edlund H: Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 1994;371:606-609.
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
Edlund, H.4
-
41
-
-
9644255692
-
Mutations in PTF1A cause pancreatic and cerebellar agenesis
-
Sellick GS, Barker KT, Stolte-Dijkstra I, Fleischmann C, Coleman RJ, Garrett C, Gloyn AL, Edghill EL, Hattersley AT, Wellauer PK, Goodwin G, Houlston RS: Mutations in PTF1A cause pancreatic and cerebellar agenesis. Nat Genet 2004;36:1301-1305.
-
(2004)
Nat Genet
, vol.36
, pp. 1301-1305
-
-
Sellick, G.S.1
Barker, K.T.2
Stolte-Dijkstra, I.3
Fleischmann, C.4
Coleman, R.J.5
Garrett, C.6
Gloyn, A.L.7
Edghill, E.L.8
Hattersley, A.T.9
Wellauer, P.K.10
Goodwin, G.11
Houlston, R.S.12
-
42
-
-
0034425698
-
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome
-
Delepine M, Nicolino M, Barrett T, Golamaully M, Lathrop GM, Julier C: EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat Genet 2000;25:406-409.
-
(2000)
Nat Genet
, vol.25
, pp. 406-409
-
-
Delepine, M.1
Nicolino, M.2
Barrett, T.3
Golamaully, M.4
Lathrop, G.M.5
Julier, C.6
-
43
-
-
33746778878
-
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus
-
Babenko AP, Polak M, Cave H, Busiah K, Czernichow P, Scharfmann R, Bryan J, Aguilar-Bryan L, Vaxillaire M, Froguel P: Activating mutations in the ABCC8 gene in neonatal diabetes mellitus. N Engl J Med 2006;355:456-466.
-
(2006)
N Engl J Med
, vol.355
, pp. 456-466
-
-
Babenko, A.P.1
Polak, M.2
Cave, H.3
Busiah, K.4
Czernichow, P.5
Scharfmann, R.6
Bryan, J.7
Aguilar-Bryan, L.8
Vaxillaire, M.9
Froguel, P.10
-
44
-
-
33744722778
-
A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes
-
Proks P, Arnold AL, Bruining J, Girard C, Flanagan SE, Larkin B, Colclough K, Hattersley AT, Ashcroft FM, Ellard S: A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes. Hum Mol Genet 2006;15:1793-1800.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1793-1800
-
-
Proks, P.1
Arnold, A.L.2
Bruining, J.3
Girard, C.4
Flanagan, S.E.5
Larkin, B.6
Colclough, K.7
Hattersley, A.T.8
Ashcroft, F.M.9
Ellard, S.10
-
45
-
-
20344380957
-
ATP channel and permanent neonatal diabetes: New insights and new treatment
-
ATP channel and permanent neonatal diabetes: new insights and new treatment. Ann Med 2005;37:186-195.
-
(2005)
Ann Med
, vol.37
, pp. 186-195
-
-
Slingerland, A.S.1
Hattersley, A.T.2
-
46
-
-
2342633204
-
Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes
-
Gloyn AL, Pearson ER, Antcliff JF, Proks P, Bruining GJ, Slingerland AS, Howard N, Srinivasan S, Silva JM, Molnes J, Edghill EL, Frayling TM, Temple IK, Mackay D, Shield JP, Sumnik Z, van Rhijn A, Wales JK, Clark P, Gorman S, Aisenberg J, Ellard S, Njolstad PR, Ashcroft FM, Hattersley AT: Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes. N Engl J Med 2004;350:1838-1849.
-
(2004)
N Engl J Med
, vol.350
, pp. 1838-1849
-
-
Gloyn, A.L.1
Pearson, E.R.2
Antcliff, J.F.3
Proks, P.4
Bruining, G.J.5
Slingerland, A.S.6
Howard, N.7
Srinivasan, S.8
Silva, J.M.9
Molnes, J.10
Edghill, E.L.11
Frayling, T.M.12
Temple, I.K.13
Mackay, D.14
Shield, J.P.15
Sumnik, Z.16
van Rhijn, A.17
Wales, J.K.18
Clark, P.19
Gorman, S.20
Aisenberg, J.21
Ellard, S.22
Njolstad, P.R.23
Ashcroft, F.M.24
Hattersley, A.T.25
more..
-
47
-
-
19944427182
-
KCNJ11 activating mutations in Italian patients with permanent neonatal diabetes
-
Massa O, Iafusco D, D'Amato E, Gloyn AL, Hattersley AT, Pasquino B, Tonini G, Dammacco F, Zanette G, Meschi F, Porzio O, Bottazzo G, Crino A, Lorini R, Cerutti F, Vanelli M, Barbetti F: KCNJ11 activating mutations in Italian patients with permanent neonatal diabetes. Hum Mutat 2005;25:22-27.
-
(2005)
Hum Mutat
, vol.25
, pp. 22-27
-
-
Massa, O.1
Iafusco, D.2
D'Amato, E.3
Gloyn, A.L.4
Hattersley, A.T.5
Pasquino, B.6
Tonini, G.7
Dammacco, F.8
Zanette, G.9
Meschi, F.10
Porzio, O.11
Bottazzo, G.12
Crino, A.13
Lorini, R.14
Cerutti, F.15
Vanelli, M.16
Barbetti, F.17
-
48
-
-
4644260056
-
Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: Patient characteristics and initial response to sulfonylurea therapy
-
Sagen JV, Raeder H, Hathout E, Shehadeh N, Gudmundsson K, Baevre H, Abuelo D, Phornphutkul C, Molnes J, Bell GI, Gloyn AL, Hattersley AT, Molven A, Sovik O, Njolstad PR X: Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy. Diabetes 2004;53:2713-2718.
-
(2004)
Diabetes
, vol.53
, pp. 2713-2718
-
-
Sagen, J.V.1
Raeder, H.2
Hathout, E.3
Shehadeh, N.4
Gudmundsson, K.5
Baevre, H.6
Abuelo, D.7
Phornphutkul, C.8
Molnes, J.9
Bell, G.I.10
Gloyn, A.L.11
Hattersley, A.T.12
Molven, A.13
Sovik, O.14
Njolstad, P.X.15
-
49
-
-
23644442552
-
ATP-sensitive potassium channelopathies: Focus on insulin secretion
-
Ashcroft FM: ATP-sensitive potassium channelopathies: focus on insulin secretion. J Clin Invest 2005;115:2047-2058.
-
(2005)
J Clin Invest
, vol.115
, pp. 2047-2058
-
-
Ashcroft, F.M.1
-
50
-
-
33646513278
-
Mutations in KCNJ11, which encodes Kir6.2, are a common cause of diabetes diagnosed in the first 6 months of life, with the phenotype determined by genotype
-
Flanagan SE, Edghill EL, Gloyn AL, Ellard S, Hattersley AT: Mutations in KCNJ11, which encodes Kir6.2, are a common cause of diabetes diagnosed in the first 6 months of life, with the phenotype determined by genotype. Diabetologia 2006;49:1190-1197.
-
(2006)
Diabetologia
, vol.49
, pp. 1190-1197
-
-
Flanagan, S.E.1
Edghill, E.L.2
Gloyn, A.L.3
Ellard, S.4
Hattersley, A.T.5
-
51
-
-
24144467758
-
Activating mutations in kir6.2 and neonatal diabetes: New clinical syndromes, new scientific insights, and new therapy
-
Hattersley AT, Ashcroft FM: Activating mutations in kir6.2 and neonatal diabetes: new clinical syndromes, new scientific insights, and new therapy. Diabetes 2005;54:2503-2513.
-
(2005)
Diabetes
, vol.54
, pp. 2503-2513
-
-
Hattersley, A.T.1
Ashcroft, F.M.2
-
52
-
-
8744262895
-
Glibenclamide treatment in permanent neonatal diabetes mellitus due to an activating mutation in Kir6.2
-
Zung A, Glaser B, Nimri R, Zadik Z: Glibenclamide treatment in permanent neonatal diabetes mellitus due to an activating mutation in Kir6.2. J Clin Endocrinol Metab 2004;89: 5504-5507.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5504-5507
-
-
Zung, A.1
Glaser, B.2
Nimri, R.3
Zadik, Z.4
-
53
-
-
21244487124
-
The C42R mutation in the Kir6.2 (KCNJ11) gene as a cause of transient neonatal diabetes, childhood diabetes, or later-onset, apparently type 2 diabetes mellitus
-
Yorifuji T, Nagashima K, Kurokawa K, Kawai M, Oishi M, Akazawa Y, Hosokawa M, Yamada Y, Inagaki N, Nakahata T: The C42R mutation in the Kir6.2 (KCNJ11) gene as a cause of transient neonatal diabetes, childhood diabetes, or later-onset, apparently type 2 diabetes mellitus. J Clin Endocrinol Metab 2005;90:3174-3178.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 3174-3178
-
-
Yorifuji, T.1
Nagashima, K.2
Kurokawa, K.3
Kawai, M.4
Oishi, M.5
Akazawa, Y.6
Hosokawa, M.7
Yamada, Y.8
Inagaki, N.9
Nakahata, T.10
-
54
-
-
10644233000
-
Molecular basis of Kir6.2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features
-
Proks P, Antcliff JF, Lippiat J, Gloyn AL, Hattersley AT, Ashcroft FM: Molecular basis of Kir6.2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features. Proc Natl Acad Sci USA 2004;101:17539-17544.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17539-17544
-
-
Proks, P.1
Antcliff, J.F.2
Lippiat, J.3
Gloyn, A.L.4
Hattersley, A.T.5
Ashcroft, F.M.6
-
55
-
-
20044389281
-
A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome
-
Proks P, Girard C, Haider S, Gloyn AL, Hattersley AT, Sansom MS, Ashcroft FM: A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome. EMBO Rep 2005;6:470-475.
-
(2005)
EMBO Rep
, vol.6
, pp. 470-475
-
-
Proks, P.1
Girard, C.2
Haider, S.3
Gloyn, A.L.4
Hattersley, A.T.5
Sansom, M.S.6
Ashcroft, F.M.7
-
56
-
-
33845518513
-
A Kir6.2 mutation causing neonatal diabetes impairs electrical activity and insulin secretion from INS-1 beta-cells
-
Tarasov AI, Welters HJ, Senkel S, Ryffel GU, Hattersley AT, Morgan NG, Ashcroft FM: A Kir6.2 mutation causing neonatal diabetes impairs electrical activity and insulin secretion from INS-1 beta-cells. Diabetes 2006;55:3075-3082.
-
(2006)
Diabetes
, vol.55
, pp. 3075-3082
-
-
Tarasov, A.I.1
Welters, H.J.2
Senkel, S.3
Ryffel, G.U.4
Hattersley, A.T.5
Morgan, N.G.6
Ashcroft, F.M.7
-
57
-
-
22744438517
-
Kir6.2 mutations causing neonatal diabetes provide new insights into Kir6.2-SUR1 interactions
-
Tammaro P, Girard C, Molnes J, Njolstad PR, Ashcroft FM: Kir6.2 mutations causing neonatal diabetes provide new insights into Kir6.2-SUR1 interactions. EMBO J 2005;24:2318-2330.
-
(2005)
EMBO J
, vol.24
, pp. 2318-2330
-
-
Tammaro, P.1
Girard, C.2
Molnes, J.3
Njolstad, P.R.4
Ashcroft, F.M.5
-
58
-
-
24944501418
-
Functional effects of KCNJ11 mutations causing neonatal diabetes: Enhanced activation by MgATP
-
Proks P, Girard C, Ashcroft FM: Functional effects of KCNJ11 mutations causing neonatal diabetes: enhanced activation by MgATP. Hum Mol Genet 2005;14:2717-2726.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2717-2726
-
-
Proks, P.1
Girard, C.2
Ashcroft, F.M.3
-
60
-
-
33748288147
-
Mutations at the same residue (R50) of Kir6.2 (KCNJ11) that cause neonatal diabetes produce different functional effects
-
Shimomura K, Girard CA, Proks P, Nazim J, Lippiat JD, Cerutti F, Lorini R, Ellard S, Hattersely AT, Barbetti F, Ashcroft FM: Mutations at the same residue (R50) of Kir6.2 (KCNJ11) that cause neonatal diabetes produce different functional effects. Diabetes 2006;55:1705-1712.
-
(2006)
Diabetes
, vol.55
, pp. 1705-1712
-
-
Shimomura, K.1
Girard, C.A.2
Proks, P.3
Nazim, J.4
Lippiat, J.D.5
Cerutti, F.6
Lorini, R.7
Ellard, S.8
Hattersely, A.T.9
Barbetti, F.10
Ashcroft, F.M.11
-
61
-
-
0033624291
-
ATP4- mediates closure of pancreatic betacell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites
-
Markworth E, Schwanstecher C, Schwanstecher M: ATP4- mediates closure of pancreatic betacell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites. Diabetes 2000;49:1413-1418.
-
(2000)
Diabetes
, vol.49
, pp. 1413-1418
-
-
Markworth, E.1
Schwanstecher, C.2
Schwanstecher, M.3
-
63
-
-
0036823728
-
Cell-type specific depression of neuronal excitability in rat hippocampus by activation of ATP-sensitive potassium channels
-
Griesemer D, Zawar C, Neumcke B: Cell-type specific depression of neuronal excitability in rat hippocampus by activation of ATP-sensitive potassium channels. Eur Biophys J 2002;31:467-477.
-
(2002)
Eur Biophys J
, vol.31
, pp. 467-477
-
-
Griesemer, D.1
Zawar, C.2
Neumcke, B.3
-
66
-
-
0026344826
-
Adenosine triphosphate-sensitive potassium channels in the cardiovascular system
-
Nichols CG, Lederer WJ: Adenosine triphosphate-sensitive potassium channels in the cardiovascular system. Am J Physiol 1991;261:H1675-H1686.
-
(1991)
Am J Physiol
, vol.261
-
-
Nichols, C.G.1
Lederer, W.J.2
-
67
-
-
0029561629
-
Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle
-
Sakura H, Ammala C, Smith PA, Gribble FM, Ashcroft FM: Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle. FEBS Lett 1995;377:338-344.
-
(1995)
FEBS Lett
, vol.377
, pp. 338-344
-
-
Sakura, H.1
Ammala, C.2
Smith, P.A.3
Gribble, F.M.4
Ashcroft, F.M.5
-
68
-
-
0036889440
-
ATP-sensitive potassium channels participate in glucose uptake in skeletal muscle and adipose tissue
-
Miki T, Minami K, Zhang L, Morita M, Gonoi T, Shiuchi T, Minokoshi Y, Renaud JM, Seino S: ATP-sensitive potassium channels participate in glucose uptake in skeletal muscle and adipose tissue. Am J Physiol Endocrinol Metab 2002;283:E1178-E1184.
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
-
-
Miki, T.1
Minami, K.2
Zhang, L.3
Morita, M.4
Gonoi, T.5
Shiuchi, T.6
Minokoshi, Y.7
Renaud, J.M.8
Seino, S.9
-
69
-
-
14644408737
-
High-dose glibenclamide can replace insulin therapy despite transitory diarrhea in early-onset diabetes caused by a novel R201L Kir6.2 mutation
-
Codner E, Flanagan S, Ellard S, Garcia H, Hattersley AT: High-dose glibenclamide can replace insulin therapy despite transitory diarrhea in early-onset diabetes caused by a novel R201L Kir6.2 mutation. Diabetes Care 2005;28:758-759.
-
(2005)
Diabetes Care
, vol.28
, pp. 758-759
-
-
Codner, E.1
Flanagan, S.2
Ellard, S.3
Garcia, H.4
Hattersley, A.T.5
-
70
-
-
24144456153
-
+ channels in neonatal diabetes: Implications for pharmacogenomic therapy
-
+ channels in neonatal diabetes: implications for pharmacogenomic therapy. Diabetes 2005;54:2645-2654.
-
(2005)
Diabetes
, vol.54
, pp. 2645-2654
-
-
Koster, J.C.1
Remedi, M.S.2
Dao, C.3
Nichols, C.G.4
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