Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer

Cancer Research

Volumn 68, Issue 4, 2008, Pages 1119-1127

  Iwanaga, Kentaro ^a   Yang, Yanan ^a   Raso, Maria Gabriela ^a   Ma, Lijiang ^a   Hanna, Amy E ^a   Thilaganathan, Nishan ^a   Moghaddam, Seyed ^a   Evans, Christopher M ^a   Li, Huaiguang ^b   Cai, Wei Wen ^b   Sato, Mitsuo ^c   Minna, John D ^c   Wu, Hong ^d   Creighton, Chad J ^b   Demayo, Francesco J ^a,b   Wistuba, Ignacio I ^a   Kurie, Jonathan M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CARCINOGENESIS; CONTROLLED STUDY; DISEASE SEVERITY; GENETIC PROCEDURES; HISTOLOGY; INFLAMMATION; LETHALITY; LUNG CANCER; NONHUMAN; ONCOGENE K RAS; PRIORITY JOURNAL; PROTEIN FUNCTION; SURVIVAL TIME; VASCULARIZATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOCARCINOMA, BRONCHIOLO-ALVEOLAR; ALLELES; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CHEMOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, RAS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION;

EID: 39449134253     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-3117     Document Type: Article

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