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Volumn 44, Issue 5, 2008, Pages 815-825

trans-Arachidonic acids induce a heme oxygenase-dependent vasorelaxation of cerebral microvasculature

Author keywords

Carbon monoxide; Cerebral vasorelaxation; Cyclic GMP; Free radicals; Heme oxygenase; Large conductance calcium dependent potassium channels; Nitrative stress; trans Arachidonic acids

Indexed keywords

1 (2 HYDROXY 5 TRIFLUOROMETHYLPHENYL) 5 TRIFLUOROMETHYL 2(3H) BENZIMIDAZOLONE; ARACHIDONIC ACID; BILIRUBIN; CARBON MONOXIDE; GUANYLATE CYCLASE; HEME OXYGENASE; IBERIOTOXIN; POTASSIUM CHANNEL; PROTOPORPHYRIN ZINC;

EID: 39149135587     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2007.11.006     Document Type: Article
Times cited : (24)

References (67)
  • 1
    • 0033966101 scopus 로고    scopus 로고
    • Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders
    • Wattanapitayakul S.K., Weinstein D.M., Holycross B.J., and Bauer J.A. Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders. FASEB J. 14 (2000) 271-278
    • (2000) FASEB J. , vol.14 , pp. 271-278
    • Wattanapitayakul, S.K.1    Weinstein, D.M.2    Holycross, B.J.3    Bauer, J.A.4
  • 2
    • 33644790277 scopus 로고    scopus 로고
    • Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis
    • Dickhout J.G., Hossain G.S., Pozza L.M., Zhou J., Lhotak S., and Austin R.C. Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. Arterioscler. Thromb. Vasc. Biol. 25 (2005) 2623-2629
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 2623-2629
    • Dickhout, J.G.1    Hossain, G.S.2    Pozza, L.M.3    Zhou, J.4    Lhotak, S.5    Austin, R.C.6
  • 3
    • 0033215190 scopus 로고    scopus 로고
    • The cardiovascular effects and implications of peroxynitrite
    • Ronson R.S., Nakamura M., and Vinten-Johansen J. The cardiovascular effects and implications of peroxynitrite. Cardiovasc. Res. 44 (1999) 47-59
    • (1999) Cardiovasc. Res. , vol.44 , pp. 47-59
    • Ronson, R.S.1    Nakamura, M.2    Vinten-Johansen, J.3
  • 4
    • 0025874048 scopus 로고
    • Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide
    • Radi R., Beckman J.S., Bush K.M., and Freeman B.A. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch. Biochem. Biophys. 288 (1991) 481-487
    • (1991) Arch. Biochem. Biophys. , vol.288 , pp. 481-487
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 5
    • 0030000690 scopus 로고    scopus 로고
    • DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite
    • Szabo C., Zingarelli B., O'Connor M., and Salzman A.L. DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 1753-1758
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 1753-1758
    • Szabo, C.1    Zingarelli, B.2    O'Connor, M.3    Salzman, A.L.4
  • 8
    • 0033966071 scopus 로고    scopus 로고
    • Augmented vasoconstriction and thromboxane formation by 15-F(2t)-isoprostane (8-iso-prostaglandin F(2alpha)) in immature pig periventricular brain microvessels
    • [discussion 525]
    • Hou X., Gobeil Jr. F., Peri K., Speranza G., Marrache A.M., Lachapelle P., Roberts II J., Varma D.R., Chemtob S., and Ellis E.F. Augmented vasoconstriction and thromboxane formation by 15-F(2t)-isoprostane (8-iso-prostaglandin F(2alpha)) in immature pig periventricular brain microvessels. Stroke 31 (2000) 516-524 [discussion 525]
    • (2000) Stroke , vol.31 , pp. 516-524
    • Hou, X.1    Gobeil Jr., F.2    Peri, K.3    Speranza, G.4    Marrache, A.M.5    Lachapelle, P.6    Roberts II, J.7    Varma, D.R.8    Chemtob, S.9    Ellis, E.F.10
  • 11
    • 0032527641 scopus 로고    scopus 로고
    • (E)-4-Hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease
    • Selley M.L. (E)-4-Hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease. Free Radic. Biol. Med. 25 (1998) 169-174
    • (1998) Free Radic. Biol. Med. , vol.25 , pp. 169-174
    • Selley, M.L.1
  • 12
    • 0035194145 scopus 로고    scopus 로고
    • Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide
    • Butterfield D.A., Drake J., Pocernich C., and Castegna A. Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide. Trends Mol. Med. 7 (2001) 548-554
    • (2001) Trends Mol. Med. , vol.7 , pp. 548-554
    • Butterfield, D.A.1    Drake, J.2    Pocernich, C.3    Castegna, A.4
  • 13
    • 0035112495 scopus 로고    scopus 로고
    • Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
    • Lovell M.A., Xie C., and Markesbery W.R. Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol. Aging 22 (2001) 187-194
    • (2001) Neurobiol. Aging , vol.22 , pp. 187-194
    • Lovell, M.A.1    Xie, C.2    Markesbery, W.R.3
  • 14
    • 33751002345 scopus 로고    scopus 로고
    • Intervention strategies for neonatal hypoxic-ischemic cerebral injury
    • Perlman J.M. Intervention strategies for neonatal hypoxic-ischemic cerebral injury. Clin. Ther. 28 (2006) 1353-1365
    • (2006) Clin. Ther. , vol.28 , pp. 1353-1365
    • Perlman, J.M.1
  • 15
    • 0034526990 scopus 로고    scopus 로고
    • Trans-arachidonic acids: new mediators of inflammation
    • Balazy M. Trans-arachidonic acids: new mediators of inflammation. J. Physiol. Pharmacol. 51 (2000) 597-607
    • (2000) J. Physiol. Pharmacol. , vol.51 , pp. 597-607
    • Balazy, M.1
  • 16
    • 1842870542 scopus 로고    scopus 로고
    • Arachidonate geometrical isomers generated by thiyl radicals: the relationship with trans lipids detected in biological samples
    • Ferreri C., Faraone Mennella M.R., Formisano C., Landi L., and Chatgilialoglu C. Arachidonate geometrical isomers generated by thiyl radicals: the relationship with trans lipids detected in biological samples. Free Radic. Biol. Med. 33 (2002) 1516-1526
    • (2002) Free Radic. Biol. Med. , vol.33 , pp. 1516-1526
    • Ferreri, C.1    Faraone Mennella, M.R.2    Formisano, C.3    Landi, L.4    Chatgilialoglu, C.5
  • 19
    • 33750871061 scopus 로고    scopus 로고
    • Peroxynitrite-mediated vasorelaxation: evidence against the formation of circulating S-nitrosothiols
    • Graves J.E., Lewis S.J., and Kooy N.W. Peroxynitrite-mediated vasorelaxation: evidence against the formation of circulating S-nitrosothiols. Am. J. Physiol. 274 (1998) H1001-H1008
    • (1998) Am. J. Physiol. , vol.274
    • Graves, J.E.1    Lewis, S.J.2    Kooy, N.W.3
  • 20
    • 0028670471 scopus 로고
    • Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart
    • Villa L.M., Salas E., Darley-Usmar V.M., Radomski M.W., and Moncada S. Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 12383-12387
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 12383-12387
    • Villa, L.M.1    Salas, E.2    Darley-Usmar, V.M.3    Radomski, M.W.4    Moncada, S.5
  • 22
    • 25844477213 scopus 로고    scopus 로고
    • Cytochrome P450/NADPH-dependent biosynthesis of 5,6-trans-epoxyeicosatrienoic acid from 5,6-trans-arachidonic acid
    • Roy U., Joshua R., Stark R.L., and Balazy M. Cytochrome P450/NADPH-dependent biosynthesis of 5,6-trans-epoxyeicosatrienoic acid from 5,6-trans-arachidonic acid. Biochem. J. 390 (2005) 719-727
    • (2005) Biochem. J. , vol.390 , pp. 719-727
    • Roy, U.1    Joshua, R.2    Stark, R.L.3    Balazy, M.4
  • 23
    • 0033523007 scopus 로고    scopus 로고
    • Nitrogen dioxide induces cis-trans-isomerization of arachidonic acid within cellular phospholipids: detection of trans-arachidonic acids in vivo
    • Jiang H., Kruger N., Lahiri D.R., Wang D., Vatele J.M., and Balazy M. Nitrogen dioxide induces cis-trans-isomerization of arachidonic acid within cellular phospholipids: detection of trans-arachidonic acids in vivo. J. Biol. Chem. 274 (1999) 16235-16241
    • (1999) J. Biol. Chem. , vol.274 , pp. 16235-16241
    • Jiang, H.1    Kruger, N.2    Lahiri, D.R.3    Wang, D.4    Vatele, J.M.5    Balazy, M.6
  • 24
    • 0029671016 scopus 로고    scopus 로고
    • Effects of the BKCa channel activator, NS1619, on rat cerebral artery smooth muscle
    • Holland M., Langton P.D., Standen N.B., and Boyle J.P. Effects of the BKCa channel activator, NS1619, on rat cerebral artery smooth muscle. Br. J. Pharmacol. 117 (1996) 119-129
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 119-129
    • Holland, M.1    Langton, P.D.2    Standen, N.B.3    Boyle, J.P.4
  • 26
    • 33847717468 scopus 로고    scopus 로고
    • Simvastatin elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and mevalonate-rho kinase pathways
    • Nagaoka T., Hein T.W., Yoshida A., and Kuo L. Simvastatin elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and mevalonate-rho kinase pathways. Invest. Ophthalmol. Vis. Sci. 48 (2007) 825-832
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 825-832
    • Nagaoka, T.1    Hein, T.W.2    Yoshida, A.3    Kuo, L.4
  • 27
  • 28
    • 0032960103 scopus 로고    scopus 로고
    • Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels
    • Kozma F., Johnson R.A., Zhang F., Yu C., Tong X., and Nasjletti A. Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels. Am. J. Physiol. 276 (1999) R1087-R1094
    • (1999) Am. J. Physiol. , vol.276
    • Kozma, F.1    Johnson, R.A.2    Zhang, F.3    Yu, C.4    Tong, X.5    Nasjletti, A.6
  • 29
    • 0036086880 scopus 로고    scopus 로고
    • Determinants of renal microvascular response to ACh: afferent and efferent arteriolar actions of EDHF
    • Wang X., and Loutzenhiser R. Determinants of renal microvascular response to ACh: afferent and efferent arteriolar actions of EDHF. Am. J. Physiol., Renal Physiol. 282 (2002) F124-F132
    • (2002) Am. J. Physiol., Renal Physiol. , vol.282
    • Wang, X.1    Loutzenhiser, R.2
  • 33
    • 0021931043 scopus 로고
    • Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole
    • Mathews J.M., Dostal L.A., and Bend J.R. Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole. J. Pharmacol. Exp. Ther. 235 (1985) 186-190
    • (1985) J. Pharmacol. Exp. Ther. , vol.235 , pp. 186-190
    • Mathews, J.M.1    Dostal, L.A.2    Bend, J.R.3
  • 34
    • 0032736712 scopus 로고    scopus 로고
    • Miconazole represses CO(2)-induced pial arteriolar dilation only under selected circumstances
    • Pelligrino D.A., Santizo R.A., and Wang Q. Miconazole represses CO(2)-induced pial arteriolar dilation only under selected circumstances. Am. J. Physiol. 277 (1999) H1484-H1490
    • (1999) Am. J. Physiol. , vol.277
    • Pelligrino, D.A.1    Santizo, R.A.2    Wang, Q.3
  • 35
    • 29444445023 scopus 로고    scopus 로고
    • Inhibition of 12- and 15-lipoxygenase activities and protection of human and tilapia low density lipoprotein oxidation by I-Tiao-Gung (glycine tomentella)
    • Chen T.Y., Shiao M.S., and Pan B.S. Inhibition of 12- and 15-lipoxygenase activities and protection of human and tilapia low density lipoprotein oxidation by I-Tiao-Gung (glycine tomentella). Lipids 40 (2005) 1171-1177
    • (2005) Lipids , vol.40 , pp. 1171-1177
    • Chen, T.Y.1    Shiao, M.S.2    Pan, B.S.3
  • 37
    • 0030923630 scopus 로고    scopus 로고
    • The heme oxygenase system: a regulator of second messenger gases
    • Maines M.D. The heme oxygenase system: a regulator of second messenger gases. Annu. Rev. Pharmacol. Toxicol. 37 (1997) 517-554
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 517-554
    • Maines, M.D.1
  • 38
    • 0030065052 scopus 로고    scopus 로고
    • NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium
    • Motterlini R., Foresti R., Intaglietta M., and Winslow R.M. NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium. Am. J. Physiol. 270 (1996) H107-H114
    • (1996) Am. J. Physiol. , vol.270
    • Motterlini, R.1    Foresti, R.2    Intaglietta, M.3    Winslow, R.M.4
  • 40
    • 4944227655 scopus 로고    scopus 로고
    • Factors, fiction and endothelium-derived hyperpolarizing factor
    • Sandow S.L. Factors, fiction and endothelium-derived hyperpolarizing factor. Clin. Exp. Pharmacol. Physiol. 31 (2004) 563-570
    • (2004) Clin. Exp. Pharmacol. Physiol. , vol.31 , pp. 563-570
    • Sandow, S.L.1
  • 41
    • 0033069799 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factor(s): species and tissue heterogeneity
    • Triggle C.R., Dong H., Waldron G.J., and Cole W.C. Endothelium-derived hyperpolarizing factor(s): species and tissue heterogeneity. Clin. Exp. Pharmacol. Physiol. 26 (1999) 176-179
    • (1999) Clin. Exp. Pharmacol. Physiol. , vol.26 , pp. 176-179
    • Triggle, C.R.1    Dong, H.2    Waldron, G.J.3    Cole, W.C.4
  • 42
    • 0028904786 scopus 로고
    • Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone
    • Harder D.R., Campbell W.B., and Roman R.J. Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone. J. Vasc. Res. 32 (1995) 79-92
    • (1995) J. Vasc. Res. , vol.32 , pp. 79-92
    • Harder, D.R.1    Campbell, W.B.2    Roman, R.J.3
  • 45
    • 0842302968 scopus 로고    scopus 로고
    • Cytochrome P450/NADPH-dependent formation of trans epoxides from trans-arachidonic acids
    • Roy U., Loreau O., and Balazy M. Cytochrome P450/NADPH-dependent formation of trans epoxides from trans-arachidonic acids. Bioorg. Med. Chem. Lett. 14 (2004) 1019-1022
    • (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 1019-1022
    • Roy, U.1    Loreau, O.2    Balazy, M.3
  • 46
  • 47
    • 0346998125 scopus 로고    scopus 로고
    • Role of cGMP in carbon monoxide-induced cerebral vasodilation in piglets
    • Koneru P., and Leffler C.W. Role of cGMP in carbon monoxide-induced cerebral vasodilation in piglets. Am. J. Physiol. 286 (2004) H304-H309
    • (2004) Am. J. Physiol. , vol.286
    • Koneru, P.1    Leffler, C.W.2
  • 50
    • 33751071823 scopus 로고    scopus 로고
    • Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines
    • Ding Y., Zhang Y.Z., Furuyama K., Ogawa K., Igarashi K., and Shibahara S. Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines. FEBS J. 273 (2006) 5333-5346
    • (2006) FEBS J. , vol.273 , pp. 5333-5346
    • Ding, Y.1    Zhang, Y.Z.2    Furuyama, K.3    Ogawa, K.4    Igarashi, K.5    Shibahara, S.6
  • 51
    • 0032055663 scopus 로고    scopus 로고
    • 2+] in cerebral arteries of rat by membrane potential and intravascular pressure
    • 2+] in cerebral arteries of rat by membrane potential and intravascular pressure. J. Physiol. 508 Pt 1 (1998) 199-209
    • (1998) J. Physiol. , vol.508 , Issue.PART 1 , pp. 199-209
    • Knot, H.J.1    Nelson, M.T.2
  • 54
    • 0037168540 scopus 로고    scopus 로고
    • Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension
    • Fessel J.P., Porter N.A., Moore K.P., Sheller J.R., and Roberts II L.J. Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 16713-16718
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 16713-16718
    • Fessel, J.P.1    Porter, N.A.2    Moore, K.P.3    Sheller, J.R.4    Roberts II, L.J.5
  • 55
    • 33646549564 scopus 로고    scopus 로고
    • Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration
    • Musiek E.S., Breeding R.S., Milne G.L., Zanoni G., Morrow J.D., and McLaughlin B. Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration. J. Neurochem. 97 (2006) 1301-1313
    • (2006) J. Neurochem. , vol.97 , pp. 1301-1313
    • Musiek, E.S.1    Breeding, R.S.2    Milne, G.L.3    Zanoni, G.4    Morrow, J.D.5    McLaughlin, B.6
  • 56
    • 0035144956 scopus 로고    scopus 로고
    • Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease
    • Reich E.E., Markesbery W.R., Roberts II L.J., Swift L.L., Morrow J.D., and Montine T.J. Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. Am. J. Pathol. 158 (2001) 293-297
    • (2001) Am. J. Pathol. , vol.158 , pp. 293-297
    • Reich, E.E.1    Markesbery, W.R.2    Roberts II, L.J.3    Swift, L.L.4    Morrow, J.D.5    Montine, T.J.6
  • 59
    • 33646436473 scopus 로고    scopus 로고
    • Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: contributions of HO-1 and HO-2 to cytoprotection
    • Parfenova H., Basuroy S., Bhattacharya S., Tcheranova D., Qu Y., Regan R.F., and Leffler C.W. Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: contributions of HO-1 and HO-2 to cytoprotection. Am. J. Physiol., Cell Physiol. 290 (2006) C1399-C1410
    • (2006) Am. J. Physiol., Cell Physiol. , vol.290
    • Parfenova, H.1    Basuroy, S.2    Bhattacharya, S.3    Tcheranova, D.4    Qu, Y.5    Regan, R.F.6    Leffler, C.W.7
  • 60
    • 2542461143 scopus 로고    scopus 로고
    • Carbon monoxide: to boldly go where NO has gone before
    • Ryter S.W., Morse D., and Choi A.M. Carbon monoxide: to boldly go where NO has gone before. Sci. STKE 2004 (2004) RE6
    • (2004) Sci. STKE , vol.2004
    • Ryter, S.W.1    Morse, D.2    Choi, A.M.3
  • 61
    • 0041842698 scopus 로고    scopus 로고
    • Effect of carbon monoxide on dopamine and glutamate uptake and cGMP levels in rat brain
    • Taskiran D., Kutay F.Z., and Pogun S. Effect of carbon monoxide on dopamine and glutamate uptake and cGMP levels in rat brain. Neuropsychopharmacology 28 (2003) 1176-1181
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1176-1181
    • Taskiran, D.1    Kutay, F.Z.2    Pogun, S.3
  • 63
    • 31344478548 scopus 로고    scopus 로고
    • Nicotine inhibits large conductance Ca(2+)-activated K(+) channels and the NO/-cGMP signaling pathway in cultured human endothelial cells
    • Kuhlmann C.R., Trumper J.R., Tillmanns H., Alexander Schaefer C., and Erdogan A. Nicotine inhibits large conductance Ca(2+)-activated K(+) channels and the NO/-cGMP signaling pathway in cultured human endothelial cells. Scand. Cardiovasc. J. 39 (2005) 348-352
    • (2005) Scand. Cardiovasc. J. , vol.39 , pp. 348-352
    • Kuhlmann, C.R.1    Trumper, J.R.2    Tillmanns, H.3    Alexander Schaefer, C.4    Erdogan, A.5
  • 65
    • 0029797975 scopus 로고    scopus 로고
    • Increased nitric oxide synthesis and action preclude choroidal vasoconstriction to hyperoxia in newborn pigs
    • Hardy P., Peri K.G., Lahaie I., Varma D.R., and Chemtob S. Increased nitric oxide synthesis and action preclude choroidal vasoconstriction to hyperoxia in newborn pigs. Circ. Res. 79 (1996) 504-511
    • (1996) Circ. Res. , vol.79 , pp. 504-511
    • Hardy, P.1    Peri, K.G.2    Lahaie, I.3    Varma, D.R.4    Chemtob, S.5
  • 66
    • 33750958560 scopus 로고    scopus 로고
    • Hyperoxic exposure leads to nitrative stress and ensuing microvascular degeneration and diminished brain mass and function in the immature subject
    • Sirinyan M., Sennlaub F., Dorfman A., Sapieha P., Gobeil F., Hardy P., Lachapelle P., and Chemtob S. Hyperoxic exposure leads to nitrative stress and ensuing microvascular degeneration and diminished brain mass and function in the immature subject. Stroke 37 (2006) 2807-2815
    • (2006) Stroke , vol.37 , pp. 2807-2815
    • Sirinyan, M.1    Sennlaub, F.2    Dorfman, A.3    Sapieha, P.4    Gobeil, F.5    Hardy, P.6    Lachapelle, P.7    Chemtob, S.8
  • 67
    • 34247171289 scopus 로고    scopus 로고
    • Hypoxia-mediated induction of heme oxygenase type I and carbon monoxide release from astrocytes protects nearby cerebral neurons from hypoxia-mediated apoptosis
    • Imuta N., Hori O., Kitao Y., Tabata Y., Yoshimoto T., Matsuyama T., and Ogawa S. Hypoxia-mediated induction of heme oxygenase type I and carbon monoxide release from astrocytes protects nearby cerebral neurons from hypoxia-mediated apoptosis. Antioxid. Redox Signal. 9 (2007) 543-552
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 543-552
    • Imuta, N.1    Hori, O.2    Kitao, Y.3    Tabata, Y.4    Yoshimoto, T.5    Matsuyama, T.6    Ogawa, S.7


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