Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase

British Journal of Pharmacology

Volumn 123, Issue 2, 1998, Pages 299-309

  Olesen, Søren Peter ^a   Drejer, Jørgen ^a   Axelsson, Oskar ^a   Moldt, Peter ^a   Bang, Lone ^b   Nielsen Kudsk, Jens Erik ^b   Busse, Rudi ^c   Mülsch, Alexander ^c  

^a NEUROSEARCH A S   (Denmark)

^b University of Copenhagen   (Denmark)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Cerebellum; Cyclic GMP; Endothelial cells; Guinea pig trachea; Nitric oxide; NS 2028 (4H 8 bromo 1,2,4 oxadiazolo(3,4 d)benz(b)(1,4)oxazin 1 one); ODQ (1H 1,2,4 oxadiazolo 4,3, a quinoxalin 1 one); Porcine coronary artery; Rabbit aorta; Soluble guanylyl cyclase

Indexed keywords

CROMAKALIM; CYCLIC GMP; ENZYME INHIBITOR; GLYCERYL TRINITRATE; GUANYLATE CYCLASE; LINSIDOMINE; N METHYL DEXTRO ASPARTIC ACID; NITROPRUSSIDE SODIUM; NS 2028; PROSTAGLANDIN F2 ALPHA; S NITROSOGLUTATHIONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; BRAIN SLICE; CEREBELLUM; CORONARY ARTERY; ENZYME INHIBITION; GUINEA PIG; HUMAN; MOUSE; PRIORITY JOURNAL; RABBIT; SMOOTH MUSCLE RELAXATION; SWINE; TRACHEA;

ANIMALS; CATTLE; CELLS, CULTURED; CEREBELLUM; CYCLIC GMP; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GUANYLATE CYCLASE; GUINEA PIGS; HEME; HUMANS; KINETICS; MALE; MICE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; OXADIAZOLES; OXAZINES; RABBITS; SOLUBILITY; SPECTROPHOTOMETRY; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE; UMBILICAL VEINS;

EID: 0031985130     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701603     Document Type: Article

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