Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration

Nature Medicine

Volumn 11, Issue 12, 2005, Pages 1339-1345

  Kermorvant Duchemin, Elsa ^a   Sennlaub, Florian ^a,b   Sirinyan, Mirna ^a,c   Brault, Sonia ^a,c   Andelfinger, Gregor ^a   Kooli, Amna ^a,c   Germain, Stéphane ^b   Ong, Huy ^d   D'Orleans Juste, Pedro ^e   Gobeil Jr , Fernand ^e   Zhu, Tang ^a   Boisvert, Chantal ^a   Hardy, Pierre ^a   Jain, Kavita ^f   Falck, J Russel ^g   Balazy, Michael ^f   Chemtob, Sylvain ^a,c  

^a UNIVERSITY OF MONTREAL   (Canada)

^b INSERM   (France)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e UNIVERSITÉ DE SHERBROOKE   (Canada)

^f NEW YORK MEDICAL COLLEGE   (United States)

^g UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; NITRIC OXIDE; THROMBOSPONDIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARACHIDONIC ACID METABOLISM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; MICROANGIOPATHY; MOUSE; NEWBORN; NITRATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINOPATHY; STRESS; UPREGULATION; VASCULAR ENDOTHELIUM;

ANIMALS; APOPTOSIS; ARACHIDONIC ACIDS; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; DIABETIC ANGIOPATHIES; DNA PRIMERS; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; IN SITU NICK-END LABELING; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; RETINAL VESSELS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUS SCROFA; TETRAZOLIUM SALTS; THIAZOLES; THROMBOSPONDIN 1;

ANIMALIA;

EID: 28644431994     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1336     Document Type: Article

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