Hyperoxic exposure leads to nitrative stress and ensuing microvascular degeneration and diminished brain mass and function in the immature subject

Stroke

Volumn 37, Issue 11, 2006, Pages 2807-2815

  Sirinyan, Mirna ^a,b   Sennlaub, Florian ^b,c   Dorfman, Allison ^a,d   Sapieha, Przemyslaw ^b   Gobeil Jr , Fernand ^e   Hardy, Pierre ^b   Lachapelle, Pierre ^d   Chemtob, Sylvain ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

^c INSERM   (France)

^d RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^e UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

Antioxidant; Brain; Hyperoxia; Nitric oxide; Vasoobliteration

Indexed keywords

3 NITROTYROSINE; 3,5 DIISOPROPYLSALICYLATE COPPER; BRAIN EXTRACT; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LECTIN; NITRATE; NITRATING AGENT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN; VASCULOTROPIN RECEPTOR 2; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD VESSEL INJURY; BLOOD VESSEL OCCLUSION; BRAIN BLOOD VESSEL; BRAIN DEVELOPMENT; BRAIN FUNCTION; BRAIN SIZE; COGNITIVE DEFECT; CONTROLLED STUDY; ENZYME ACTIVITY; EVOKED VISUAL RESPONSE; EXPOSURE; HYPEROXIA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUNG DISEASE; MICROANGIOPATHY; MOLECULAR MIMICRY; NEWBORN; NITRATION; NITRATIVE STRESS; NONHUMAN; OXYGEN TENSION; PREMATURITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETROLENTAL FIBROPLASIA; AGE; ANIMAL; ATROPHY; BRAIN; COMPARATIVE STUDY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROCIRCULATION; PATHOLOGY; SPRAGUE DAWLEY RAT;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ATROPHY; BRAIN; MICROCIRCULATION; NITRATES; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33750958560     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000245082.19294.ff     Document Type: Article

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