Synthesis, adenosine receptor binding and 3D-QSAR of 4-substituted 2-(2′-furyl)-1,2,4-triazolo[1,5-a]quinoxalines

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 4, 2008, Pages 2103-2113

  Martínez, Ana ^a   Gutiérrez de Terán, Hugo ^a   Brea, José ^a   Raviña, Enrique ^a   Loza, Maria Isabel ^a   Cadavid, Maria Isabel ^a   Sanz, Ferran ^b   Vidal, Bernat ^c   Segarra, Victor ^c   Sotelo, Eddy ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^c Almirall ^*  (Spain)

Author keywords

1,2,4 Triazolo 1,5 a quinoxalines; 3D QSAR; Adenosine receptor binding

Indexed keywords

4 AMINO 2 (2' FURYL) 1,2,4 TRIAZOLO[1,5 A]QUINOXALINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DATA ANALYSIS; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; FEMALE; HUMAN; HUMAN CELL; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

HUMANS; LIGANDS; PROTEIN BINDING; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUINOXALINES; RECEPTORS, PURINERGIC P1;

EID: 39049143861     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.10.103     Document Type: Article

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