1,3-dialkylxanthine derivatives having high potency as antagonists at human A(2B) adenosine receptors

Drug Development Research

Volumn 47, Issue 1, 1999, Pages 45-53

  Jacobson, Kenneth A ^a   Ijzerman, Ad P ^b   Linden, Joel ^c  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b LEIDEN UNIVERSITY   (Netherlands)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Alkylxanthines; Cyclic AMP; G protein coupled receptors; Purines; Radioligand; Structure activity relationships

Indexed keywords

ADENOSINE RECEPTOR BLOCKING AGENT; ENPROFYLLINE; XANTHINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; COMPETITIVE INHIBITION; DRUG EFFECT; DRUG POTENCY; LIGAND BINDING; MEMBRANE BINDING; NONHUMAN; RADIOIODINATION; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

EID: 0033014225     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199905)47:1<45::AID-DDR6>3.0.CO;2-U     Document Type: Article

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