AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression

Development

Volumn 135, Issue 2, 2008, Pages 401-410

  Yeh, Jing Ruey J ^a,b,c   Munson, Kathleen M ^a,b,c   Chao, Yvonne L ^a,b   Peterson, Quinn P ^a,b   MacRae, Calum A ^a,b   Peterson, Randall T ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

Hematopoiesis; Leukemia; Myeloid; Zebrafish

Indexed keywords

AML1 ETO FUSION PROTEIN; HEMATOPOIETIC STEM CELL FACTOR SCL; HISTONE DEACETYLASE INHIBITOR; ONCOPROTEIN; STEM CELL FACTOR; TRANSCRIPTION FACTOR GATA 1; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL FATE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; FUSION GENE; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; HEMATOPOIETIC STEM CELL; NONHUMAN; PRIORITY JOURNAL; STRUCTURAL HOMOLOGY; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOOD CELLS; CARDIOVASCULAR SYSTEM; CELL LINEAGE; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DOWN-REGULATION; EMBRYO, NONMAMMALIAN; ERYTHROID PROGENITOR CELLS; ERYTHROPOIESIS; GATA1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIETIC SYSTEM; HUMANS; HYDROXAMIC ACIDS; LEUKEMIA, MYELOID, ACUTE; MONOCYTES; ONCOGENE PROTEINS, FUSION; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION, GENETIC; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 38949180229     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.008904     Document Type: Article

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