Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair

Journal of Clinical Investigation

Volumn 112, Issue 11, 2003, Pages 1751-1761

  Alcalay, Myriam ^a,b   Meani, Natalia ^a,b   Gelmetti, Vania ^a,b   Fantozzi, Anna ^a,b   Fagioli, Marta ^c   Orleth, Annette ^c   Riganelli, Daniela ^c   Sebastiani, Carla ^c   Cappelli, Enrico ^d   Casciari, Cristina ^c   Sciurpi, Maria Teresa ^c   Mariano, Angela Rosa ^c   Minardi, Simone Paolo ^b   Luzi, Lucilla ^a,b   Muller, Heiko ^a,b   Di Fiore, Pier Paolo ^a,b   Frosina, Guido ^d   Pelicci, Pier Giuseppe ^a,b  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^c UNIVERSITY OF PERUGIA   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE MYELOID LEUKEMIA FUSION PROTEIN; DNA; EIGHT TWENTY ONE PROTEIN; GENE PRODUCT; HYBRID PROTEIN; NOTCH1 RECEPTOR; PROMYELOCYTIC LEUKEMIA PROTEIN; PROMYELOCYTIC LEUKEMIA ZINC FINGER PROTEIN; RETINOIC ACID RECEPTOR ALPHA; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CANCER SUSCEPTIBILITY; CELL RENEWAL; CELL STRAIN U937; CHROMOSOME REARRANGEMENT; DNA DAMAGE; DNA MICROARRAY; DNA REPAIR; EXCISION REPAIR; GENE CONTROL; GENE DEREGULATION; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE INDUCTION; GENE MUTATION; GENE REPRESSION; HUMAN; HUMAN CELL; LEUKEMIC POTENTIAL; PHENOTYPE; PRELEUKEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE;

EID: 0347951358     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI17595     Document Type: Article

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