Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation

Molecular and Cellular Neuroscience

Volumn 37, Issue 2, 2008, Pages 271-283

  Hendricks, Michael ^a,b   Mathuru, Ajay Sriram ^a   Wang, Hui ^a,b   Silander, Olin ^c   Kee, Michelle Zhi Ling ^a   Jesuthasan, Suresh ^a,b  

^a TEMASEK LIFE SCIENCES LABORATORY   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c ETH ZURICH   (Switzerland)

Author keywords

4E BP1; Commissure; Eph; Guidepost; Habenula; Midline crossing; Mycbp2; PAM; Phr1; Receptor localization; Scaffold; Tsc2; Wnt

Indexed keywords

EPHRIN RECEPTOR; ESROM PROTEIN; GENE PRODUCT; RYK PROTEIN; TUBERIN; UNCLASSIFIED DRUG; WNT4 PROTEIN; WNT4A PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN COMMISSURE; CONTROLLED STUDY; ELECTROPORATION; EMBRYO; HABENULA; MOUSE; MUTANT; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; ZEBRA FISH;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELLS, CULTURED; DOWN-REGULATION; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH CONES; HABENULA; MICROSCOPY, VIDEO; MIXED FUNCTION OXYGENASES; NEURAL PATHWAYS; RABBITS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, EPH FAMILY; TUMOR SUPPRESSOR PROTEINS; WNT PROTEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 38849202492     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2007.10.002     Document Type: Article

References (71)

1. Bate C.M. Pioneer neurones in an insect embryo. Nature 260 (1976) 54-56
2. Bentley D., and Caudy M. Pioneer axons lose directed growth after selective killing of guidepost cells. Nature 304 (1983) 62-65
3. Bovolenta P., and Dodd J. Guidance of commissural growth cones at the floor plate in embryonic rat spinal cord. Development 109 (1990) 435-447
4. Bovolenta P., and Dodd J. Perturbation of neuronal differentiation and axon guidance in the spinal cord of mouse embryos lacking a floor plate: analysis of Danforth's short-tail mutation. Development 113 (1991) 625-639
5. Bovolenta P., and Mason C. Growth cone morphology varies with position in the developing mouse visual pathway from retina to first targets. J. Neurosci. 7 (1987) 1447-1460
6. Brittis P.A., Lu Q., and Flanagan J.G. Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target. Cell 110 (2002) 223-235
7. Burgess R.W., Peterson K.A., Johnson M.J., Roix J.J., Welsh I.C., and O'Brien T.P. Evidence for a conserved function in synapse formation reveals Phr1 as a candidate gene for respiratory failure in newborn mice. Mol. Cell. Biol. 24 (2004) 1096-1105
8. Canal I., Acebes A., and Ferrus A. Single neuron mosaics of the Drosophila gigas mutant project beyond normal targets and modify behavior. J. Neurosci. 18 (1998) 999-1008
9. Caudy M., and Bentley D. Pioneer growth cone morphologies reveal proximal increases in substrate affinity within leg segments of grasshopper embryos. J. Neurosci. 6 (1986) 364-379
10. Charron F., Stein E., Jeong J., McMahon A.P., and Tessier-Lavigne M. The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell 113 (2003) 11-23
11. Choi J., Adames N., Chan T., Zeng C., Cooper J., and Zheng X. TOR signaling regulates microtubule structure and function. Curr. Biol. 10 (2000) 861-864
12. Collins C.A., Wairkar Y.P., Johnson S.L., and DiAntonio A. Highwire restrains synaptic growth by attenuating a MAP kinase signal. Neuron 51 (2006) 57-69
13. Cook G., Tannahill D., and Keynes R. Axon guidance to and from choice points. Curr. Opin. Neurobiol. 8 (1998) 64-72
14. D'Souza J., Hendricks M., Le Guyader S., Subburaju S., Grunewald B., Scholich K., and Jesuthasan S. Formation of the retinotectal projection requires Esrom, an ortholog of PAM (protein associated with Myc). Development 132 (2005) 247-256
15. Dickson B.J. Molecular mechanisms of axon guidance. Science 298 (2002) 1959-1964
16. Dodd J., Morton S.B., Karagogeos D., Yamamoto M., and Jessell T.M. Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron 1 (1988) 105-116
17. Edgar R.C. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res. 32 (2004) 1792-1797
18. Flanagan J.G., and Van Vactor D. Through the looking glass: axon guidance at the midline choice point. Cell 92 (1998) 429-432
19. Garbe D.S., and Bashaw G.J. Axon guidance at the midline: from mutants to mechanisms. Crit. Rev. Biochem. Mol. Biol. 39 (2004) 319-341
20. Guo Q., Xie J., Dang C., Liu E., and Bishop J. Identification of a large Myc-binding protein that contains RCC1-like repeats. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 9172-9177
21. Halloran M.C., and Kalil K. Dynamic behaviors of growth cones extending in the corpus callosum of living cortical brain slices observed with video microscopy. J. Neurosci. 14 (1994) 2161-2177
22. Han, S., Witt, R., Santos, T., Polizzano, C., Sabatini, B., Ramesh, V., 2006. Pam functions as an E3 ubiquitin ligase and regulates the Tsc2 protein Tuberin in neurons, Program No. 295.65, Society for Neuroscience.
23. Hatta K., Tsujii H., and Omura T. Cell tracking using a photoconvertible fluorescent protein. Nat. Prot. 1 (2006) 1-8
24. Hendricks M., and Jesuthasan S. Asymmetric innervation of the habenula in zebrafish. J. Comp. Neurol. 502 (2007) 611-619
25. Hendricks M., and Jesuthasan S. Electroporation-based methods for in vivo, whole mount and primary culture analysis of zebrafish brain development. Neural Develop. 2 (2007) 6
26. Inoki K., Li Y., Zhu T., Wu J., and Guan K. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 4 (2002) 648-657
27. Inoki K., Li Y., Xu T., and Guan K.L. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev. 17 (2003) 1829-1834
28. Jevince A., Kadison S., Pittman A., Chien C., and Kaprielian Z. Distribution of EphB receptors and ephrin-B1 in the developing vertebrate spinal cord. J. Comp. Neurol. 497 (2006) 734-750
29. Jiang X., and Yeung R. Regulation of microtubule-dependent protein transport by the TSC2/mammalian target of rapamycin pathway. Cancer Res. 66 (2006) 5258-5269
30. Kadison S.R., Murakami F., Matise M.P., and Kaprielian Z. The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord. Dev. Biol. 296 (2006) 499-513
31. Kaprielian Z., Runko E., and Imondi R. Axon guidance at the midline choice point. Dev. Dyn. 221 (2001) 154-181
32. Keeble T.R., Halford M.M., Seaman C., Kee N., Macheda M., Anderson R.B., Stacker S.A., and Cooper H.M. The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum. J. Neurosci. 26 (2006) 5840-5848
33. Keleman K., Rajagopalan S., Cleppien D., Teis D., Paiha K., Huber L.A., Technau G.M., and Dickson B.J. Comm sorts robo to control axon guidance at the Drosophila midline. Cell 110 (2002) 415-427
34. Kennedy T.E., T.S., de la Torre J.R., and Tessier-Lavigne M. Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord. Cell 78 (1994) 425-435
35. Kidd T., Brose K., Mitchell K.J., Fetter R.D., and Tessier-Lavigne M. Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors. Cell 92 (1998) 205-215
36. Kim P., Lu L., Xia Y., and Gerstein M. Relating three-dimensional structures to protein networks provides evolutionary insights. Science 314 (2006) 1938-1941
37. Knox S., Ge H., Dimitroff B., Ren Y., Howe K., Arsham A., Easterday M., Neufeld T., O'connor M., and Selleck S. Mechanisms of TSC-mediated control of synapse assembly and axon guidance. PLoS ONE (2007) e375
38. Le Guyader S., Maier J., and Jesuthasan S. Esrom, an ortholog of PAM (protein associated with c-myc), regulates pteridine synthesis in the zebrafish. Dev. Biol. 277 (2005) 378-386
39. Lewcock J.W., Genoud N., Lettieri K., and Pfaff S.L. The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics. Neuron (2007) 10.1016/j.neuron.2007.09.009
40. Lindwall C., Fothergill T., and Richards L. Commissure formation in the mammalian forebrain. Curr. Opin. Neurobiol. 17 (2007) 3-14
41. Long H., Sabatier C., Ma L., Plump A., Yuan W., Ornitz D.M., Tamada A., Murakami F., Goodman C.S., and Tessier-Lavigne M. Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Neuron 42 (2004) 213-223
42. Lustig M., Erskine L., Mason C.A., Grumet M., and Sakurai T. Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions. J. Comp. Neurol. 434 (2001) 12-28
43. Matsui T., Raya A., Kawakami Y., Callol-Massot C., Capdevila J., Rodriguez-Esteban C., and Izpisua Belmonte J.C. Noncanonical Wnt signaling regulates midline convergence of organ primordia during zebrafish development. Genes Dev. 19 (2005) 164-175
44. Murthy V., Han S., Beauchamp R.L., Smith N., Haddad L.A., Ito N., and Ramesh V. Pam and its ortholog highwire interact with and may negatively regulate the TSC1. TSC2 complex. J. Biol. Chem. 279 (2004) 1351-1358
45. Myers P.Z., and Bastiani M.J. Growth cone dynamics during the migration of an identified commissural growth cone. J. Neurosci. 13 (1993) 127-143
46. Nakata K., Abrams B., Grill B., Goncharov A., Huang X., Chisholm A.D., and Jin Y. Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development. Cell 120 (2005) 407-420
47. Orioli D., Henkemeyer M., Lemke G., Klein R., and Pawson T. Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 15 (1996) 6035-6049
48. Pierre S.C., Hausler J., Birod K., Geisslinger G., and Scholich K. PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate. EMBO J. 23 (2004) 3031-3040
49. Piper M., and Holt C. RNA translation in axons. Annu. Rev. Cell Dev. Biol. 20 (2004) 505-523
50. Plas D.R., and Thompson C.B. Akt activation promotes degradation of tuberin and FOXO3a via the proteasome. J. Biol. Chem. 278 (2003) 12361-12366
51. Richards L.J., Koester S.E., Tuttle R., and O'Leary D.D. Directed growth of early cortical axons is influenced by a chemoattractant released from an intermediate target. J. Neurosci. 17 (1997) 2445-2458
52. Ronquist F., and Huelsenbeck J.P. MYRBAYES 3: Bayesian phylogenetic inference under mixed models. Bioinformatics 19 (2003) 1572-1574
53. Rosner M., Freilinger A., and Hengstschlager M. The tuberous sclerosis genes and regulation of the cyclin-dependent kinase inhibitor p27. Mutat. Res. 613 (2006) 10-16
54. Sabatier C., Plump A.S., Ma L., Brose K., Tamada A., Murakami F., Lee E.Y.-H.P., and Tessier-Lavigne M. The divergent robo family protein Rig-1/Robo3 is a negative regulator of Slit responsiveness required for midline crossing by commissural axons. Cell 117 (2004) 157-169
55. Schaefer A.M., Hadwiger G.D., and Nonet M.L. rpm-1, a conserved neuronal gene that regulates targeting and synaptogenesis in C. elegans. Neuron 26 (2000) 345-356
56. Schmitt A.M., Shi J., Wolf A.M., Lu C.C., King L.A., and Zou Y. Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping. Nature 439 (2006) 31-37
57. Scholich K., Pierre S., and Patel T.B. Protein associated with Myc (PAM) is a potent inhibitor of adenylyl cyclases. J. Biol. Chem. 276 (2001) 47583-47589
58. Shirasaki R., Katsumata R., and Murakami F. Change in chemoattractant responsiveness of developing axons at an intermediate target. Science 279 (1998) 105-107
59. Stoeckli E.T., and Landmesser L.T. Axonin-1, Nr-CAM, and Ng-CAM play different roles in the in vivo guidance of chick commissural neurons. Neuron 14 (1995) 1165-1179
60. Tavazoie S., Alvarez V., Ridenour D., Kwiatkowski D., and Sabatini B. Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2. Nat. Neurosci. 8 (2005) 1727-1734
61. Tee A.R., Anjum R., and Blenis J. Inactivation of the tuberous sclerosis complex-1 and -2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and -independent phosphorylation of tuberin. J. Biol. Chem. 278 (2003) 37288-37296
62. Tee A.R., Manning B.D., Roux P.P., Cantley L.C., and Blenis J. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. Curr. Biol. 13 (2003) 1259-1268
63. Tessier-Lavigne M., and Goodman C.S. The molecular biology of axon guidance. Science 274 (1996) 1123-1133
64. Tosney K.W., and Landmesser L.T. Growth cone morphology and trajectory in the lumbosacral region of the chick embryo. J. Neurosci. 5 (1985) 2345-2358
65. Wan H.I., DiAntonio A., Fetter R.D., Bergstrom K., Strauss R., and Goodman C.S. Highwire regulates synaptic growth in Drosophila. Neuron 26 (2000) 313-329
66. Wu C., Wairkar Y.P., Collins C.A., and DiAntonio A. Highwire function at the Drosophila neuromuscular junction: spatial, structural and temporal requirements. J. Neurosci. 25 (2005) 9557-9566
67. Yang Z. PAML: A program package for phylogenetic analysis by maximum likelihood. Comput. Appl. Biosci. 13 (1997) 555-556
68. York B., Lou D., and Noonan D.J. Tuberin nuclear localization can be regulated by phosphorylation of its carboxyl terminus. Mol. Cancer Res. 4 (2006) 885-897
69. Zallen J.A., Yi B.A., and Bargmann C.I. The conserved immunoglobulin superfamily member SAX-3/Robo directs multiple aspects of axon guidance in C. elegans. Cell 92 (1998) 217-227
70. Zhang Y., Gao X., Saucedo L.J., Ru B., Edgar B.A., and Pan D. Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins. Nat. Cell Biol. 5 (2003) 578-581
71. Zhen M., Huang X., Bamber B., and Jin Y. Regulation of presynaptic terminal organization by C. elegans RPM-1, a putative guanine nucleotide exchanger with a RING-H2 finger domain. Neuron 26 (2000) 331-343