Proteasome activation during cardiac hypertrophy by the chaperone H11 Kinase/Hsp22

Cardiovascular Research

Volumn 77, Issue 3, 2008, Pages 497-505

  Hedhli, Nadia ^a   Wang, Li ^a   Wang, Qian ^a   Rashed, Eman ^a   Tian, Yimin ^a   Sui, Xiangzhen ^a   Madura, Kiran ^b   Depre, Christophe ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Growth factors; Hypertrophy; Transgenic animal models

Indexed keywords

EPOXOMICIN; HEAT SHOCK PROTEIN 22; LACTACYSTIN; PROTEASOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CELL ISOLATION; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOSOL; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME REGULATION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; CARDIOMEGALY; CELL PROLIFERATION; ENZYME ACTIVATION; HSP20 HEAT-SHOCK PROTEINS; MICE; MICE, TRANSGENIC; MUSCLE PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 38849202469     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvm054     Document Type: Article

References (34)

1. Hedhli N, Pelat M, Depre C. Protein turnover in cardiac cell growth and survival. Cardiovasc Res 2005;68:186-196.
2. Glickman MH, Ciechanover A. The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 2002;82:373-428.
3. Zolk O, Schenke C, Sarikas A. The ubiquitin-proteasome system: focus on the heart. Cardiovasc Res 2006;70:410-421.
4. Powell SR. The ubiquitin-proteasome system in cardiac physiology and pathology. Am J Physiol Heart Circ Physiol 2006;291:H1-H19.
5. Vabulas R, Hartl F. Protein synthesis upon acute nutrient restriction relies on proteasome function. Science 2005;310:1960-1963.
6. Takeda K, Yanagida M. Regulation of nuclear proteasome by Rhp6/Ubc2 through ubiquitination and destruction of the sensor and anchor Cut8. Cell 2005;122:393-405.
7. Depre C, Wang Q, Yan L, Hedhli N, Peter P, Chen L et al. Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy. Circulation 2006;114:1821-1828.
8. Smith C, Yu Y, Kulka M, Aurelian L. A novel human gene similar to the protein kinase (Pk) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (Icp10) codes for a serine-threonine Pk and Is expressed in melanoma cells. J Biol Chem 2000;275:25690-25699.
9. Danan IJ, Rashed ER, Depre C. Therapeutic potential of H11 kinase for the ischemic heart. Cardiovasc Drug Revs 2007;25:14-29.
10. Depre C, Hase M, Gaussin V, Zajac A, Wang L, Hittinger L et al. H11 kinase is a novel mediator of myocardial hypertrophy in vivo. Circ Res 2002;91:1007-1014.
11. McMullen J, Sherwood M, Tarnavski O, Zhang L, Dorfman A, Shioi T et al. Inhibition of Mtor signaling with Rapamycin regresses established cardiac hypertrophy induced by pressure overload. Circulation 2004;109:3050-3055.
12. 2-adrenergic receptor. Science 1994;264:582-586.
13. Chen L, Madura K. Rad23 promotes the targeting of proteolytic substrates to the proteasome. Mol Cell Biol 2002;22:4902-4913.
14. Depre C, Wang L, Sui X, Qiu H, Hong C, Hedhli N et al. H11 kinase prevents myocardial infarction by pre-emptive preconditioning of the heart. Circ Res 2006;98:280-288.
15. Chen L, Madura K. Increased proteasome activity, ubiquitin-conjugating enzymes, and Eef1a translation factor detected in breast cancer tissue. Cancer Res 2005;65:5599-5606.
16. Chomczynski P, Sacchi N. Single-step method of Rna isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
17. Depre C, Shipley G, Chen W, Han Q, Doenst T, Moore M et al. Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy. Nat Med 1998;4:1269-1275.
18. Depre C, Wang L, Tomlinson J, Gaussin V, Abdellatif M, Topper J et al. Characterization of Pdja1, a cardiac-specific chaperone found by genomic profiling of the post-ischemic swine heart. Cardiovasc Res 2003;58:126-135.
19. Abdellatif M, Packer S, Michael L, Zhang D, Charng M, Schneider M. A Ras-dependent pathway regulates Rna polymerase Ii phosphorylation in cardiac myocytes: implications for cardiac hypertrophy. Mol Cell Biol 1998;18:6729-6736.
20. Gomes AV, Zong C, Edmondson RD, Li X, Stefani E, Zhang J et al. Mapping the Murine Cardiac 26s Proteasome Complexes. Circ Res 2006;99:362-371.
21. Rechsteiner M, Hill C. Mobilizing the Proteolytic Machine: Cell Biological Roles of Proteasome Activators and Inhibitors. Trends Cell Biol 2005;15:27-33.
22. Lowe JE, Stock D, Jap B, Zwickl P, Baumeister W, Huber R. Crystal structure of the 20s proteasome from the archeon T. Acidophilum at 3.4 a resolution. Science 1995;268:533-539.
23. Meng L, Mohan R, Kwok BHB, Elofsson M, Sin N, Crews CM. Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. PNAS 1999;96:10403-10408.
24. Powell SR, Davis KJ, Divald A. Optimal determination of heart tissue 26s-proteasome activity requires maximal stimulating Atp concentrations. J Mol Cell Cardiol 2007;42:265-269.
25. Parcellier A, Schmitt E, Gurbuxani S, Seigneurin-Berny D, Pance A, Chantome A et al. Hsp27 is a ubiquitin-binding protein involved in I-Kb-alpha proteasomal degradation. Mol Cell Biol 2003;23:5790- 5802.
26. Parcellier A, Brunet M, Schmitt E, Col E, Didelot C, Hammann A et al. Hsp27 favors ubiquitination and proteasomal degradation of P27kip1 and helps S-phase re-entry in stressed cells. FASEB J 2006;20:1179- 1181.
27. Craiu A, Gaczynska M, Akopian T, Gramm CF, Fenteany G, Goldberg AL et al. Lactacystin and clasto-lactacystin beta -lactone modify multiple proteasome beta -subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation. J Biol Chem 1997;272:13437-13445.
28. Kessler B, Tortorella D, Altun M, Kisselev A, Fiebiger E, Hekking B et al. Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits. Chem Biol 2001;8:913-929.
29. Skurk C, Izumiya Y, Maatz H, Razeghi P, Shiojima I, Sandri M et al. The Foxo3a transcription factor regulates cardiac myocyte size downstream of Akt signaling. J Biol Chem 2005;280:20814-20823.
30. Plas DR, Thompson CB. Akt activation promotes degradation of Tuberin and Foxo3a via the proteasome. J Biol Chem 2003;278:12361-12366.
31. Tomita H, Nazmy M, Kajimoto K, Yehia G, Molina CA, Sadoshima J. Inducible camp early repressor (Icer) is a negative-feedback regulator of cardiac hypertrophy and an important mediator of cardiac myocyte apoptosis in response to fBetag-adrenergic receptor stimulation. Circ Res 2003;93:12-22.
32. Marciniak S, Ron D. Endoplasmic reticulum stress signaling in disease. Physiol Rev 2006;86:1133-1149.
33. Xu C, Bailly-Maitre B, Reed JC. Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 2005;115:2656-2664.
34. Kim M, Seit-Nebi A, Gusev N. The problem of protein kinase activity of small heat shock protein Hsp22 (H11 or Hspb8). Biochem Biophys Res Commun 2004;325:649-652.