메뉴 건너뛰기




Volumn 29, Issue 1, 2008, Pages 73-77

Protective effects of Peganum harmala extracts on thiourea-induced diseases in adult male rat

Author keywords

Cancer; Hepatotoxicity; Peganum harmala; Rat; Thiourea

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CHLOROFORM; NEURON SPECIFIC ENOLASE; PEGANUM HARMALA EXTRACT; THIOUREA; THYROGLOBULIN;

EID: 38849164177     PISSN: 02548704     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (29)

References (49)
  • 1
    • 0017648217 scopus 로고
    • Cardiovascular actions of three harmal alkaloids,harmine, harmaline and harmalol
    • Aarons, DH., G.J. Rossi and R.F. Orzechowski: Cardiovascular actions of three harmal alkaloids,harmine, harmaline and harmalol. J. Pharm. Sci., 66, 1244-1248 (1977).
    • (1977) J. Pharm. Sci , vol.66 , pp. 1244-1248
    • Aarons, D.H.1    Rossi, G.J.2    Orzechowski, R.F.3
  • 2
    • 0030472746 scopus 로고    scopus 로고
    • Action of harman 1-methyl- b-carboline on the brain: Body temperature and in vivo efflux of 5-HT from hippocampus of the rat
    • Adell, A., T.A. Biggs and R.D. Myers: Action of harman 1-methyl- b-carboline on the brain: Body temperature and in vivo efflux of 5-HT from hippocampus of the rat. Neuropharmacology, 35, 1101-1107 (1996).
    • (1996) Neuropharmacology , vol.35 , pp. 1101-1107
    • Adell, A.1    Biggs, T.A.2    Myers, R.D.3
  • 3
    • 0037048727 scopus 로고    scopus 로고
    • Antioxidant activity of grains
    • Adom, K. and R. H.Liu: Antioxidant activity of grains. J. Agric. Food Chem., 50, 6182-6187 (2002).
    • (2002) J. Agric. Food Chem , vol.50 , pp. 6182-6187
    • Adom, K.1    Liu, R.H.2
  • 4
    • 33645099301 scopus 로고    scopus 로고
    • Stress oxydant et vieillissement.
    • Barouki, R.: Stress oxydant et vieillissement. Med. Sci., 22, 266-272 (2006).
    • (2006) Med. Sci , vol.22 , pp. 266-272
    • Barouki, R.1
  • 5
    • 0030600524 scopus 로고    scopus 로고
    • Harman-induced changes of extracellular concentrations of neurotransmitters in the nucleus accumbens of rats
    • Baum, S.S., R. Hill and H. Rommelspacher: Harman-induced changes of extracellular concentrations of neurotransmitters in the nucleus accumbens of rats. Eur. J. Pharm., 314, 75-82 (1996).
    • (1996) Eur. J. Pharm , vol.314 , pp. 75-82
    • Baum, S.S.1    Hill, R.2    Rommelspacher, H.3
  • 6
    • 3242765427 scopus 로고    scopus 로고
    • Updating the evidence that physical activity is good for health: An epidemiological review 2000-2003
    • Bauman, A.E.: Updating the evidence that physical activity is good for health: An epidemiological review 2000-2003. J. Sci. Med. Sport., 7, 6-19 (2004).
    • (2004) J. Sci. Med. Sport , vol.7 , pp. 6-19
    • Bauman, A.E.1
  • 7
    • 77957174895 scopus 로고
    • Comparative carcinogenicity of ethylenethiourea with or without perinatal exposure in rat and mice
    • Chhabra, R.S., S. Eustis, J.K. Haseman, P.J. Kurtz and B.D. Carlton: Comparative carcinogenicity of ethylenethiourea with or without perinatal exposure in rat and mice. Fund. Appl. Toxicol., 18, 405-417 (1992).
    • (1992) Fund. Appl. Toxicol , vol.18 , pp. 405-417
    • Chhabra, R.S.1    Eustis, S.2    Haseman, J.K.3    Kurtz, P.J.4    Carlton, B.D.5
  • 8
    • 0034903590 scopus 로고    scopus 로고
    • Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: Description of specific patterns
    • Debersaca, P.J., M. Heydelb, M. Amiotc, H. Goudonnet, Y. Artur, M. Suschetet and M.H. Siess: Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: Description of specific patterns. Food Chem. Toxicol., 39, 907-918 (2001).
    • (2001) Food Chem. Toxicol , vol.39 , pp. 907-918
    • Debersaca, P.J.1    Heydelb, M.2    Amiotc, M.3    Goudonnet, H.4    Artur, Y.5    Suschetet, M.6    Siess, M.H.7
  • 9
    • 2942657311 scopus 로고    scopus 로고
    • Commonly consumed and naturally occurring dietary substances affect biomarkers of oxidative stress and DNA damage in healthy rats
    • Farombi, E.O., M. Hansen, G. Ravn-Haren, P. Moller and L.O. Dragsted: Commonly consumed and naturally occurring dietary substances affect biomarkers of oxidative stress and DNA damage in healthy rats. Food Chem. Toxicol., 42, 1315-1322 (2004).
    • (2004) Food Chem. Toxicol , vol.42 , pp. 1315-1322
    • Farombi, E.O.1    Hansen, M.2    Ravn-Haren, G.3    Moller, P.4    Dragsted, L.O.5
  • 10
    • 0026501972 scopus 로고
    • Neuron-specific enolase: A serum marker in seminoma
    • Fossa, S.D., O. Klepp and E. Paus: Neuron-specific enolase: A serum marker in seminoma. Brit. J. Cancer, 65, 297-299 (1992).
    • (1992) Brit. J. Cancer , vol.65 , pp. 297-299
    • Fossa, S.D.1    Klepp, O.2    Paus, E.3
  • 11
    • 0023941249 scopus 로고
    • Drinking water guideline for ethylenethiourea, a metabolite of ethylene bisdithiocarbamate
    • Frakes, R.A.: Drinking water guideline for ethylenethiourea, a metabolite of ethylene bisdithiocarbamate. Reg. Toxicol. Pharmacol., 8, 207-218 (1988).
    • (1988) Reg. Toxicol. Pharmacol , vol.8 , pp. 207-218
    • Frakes, R.A.1
  • 12
    • 0009538299 scopus 로고
    • Hydroxyl radical scavenging activity of flavonoids
    • Husain, S.R., J. Cillard and P. Cillard: Hydroxyl radical scavenging activity of flavonoids. Phytochemistry, 26, 2489-2491 (1987).
    • (1987) Phytochemistry , vol.26 , pp. 2489-2491
    • Husain, S.R.1    Cillard, J.2    Cillard, P.3
  • 13
    • 7044224312 scopus 로고    scopus 로고
    • Hepatoprotective and free radical scavenging activities of phenolic petrosins and flavonoids isolated from Equisetum arvense
    • Hyuncheol, O., K. Do-Hoon, C. Jung-Hee and K. Youn-Chut: Hepatoprotective and free radical scavenging activities of phenolic petrosins and flavonoids isolated from Equisetum arvense. J. Ethnopharmacol., 95, 421-424 (2004).
    • (2004) J. Ethnopharmacol , vol.95 , pp. 421-424
    • Hyuncheol, O.1    Do-Hoon, K.2    Jung-Hee, C.3    Youn-Chut, K.4
  • 15
    • 3242741237 scopus 로고    scopus 로고
    • Antioxidant and anticancer activities of organic extracts from Platycodon grandiflorum A. De Candolle roots
    • Ji-Young, L., H. Woo-Ik and L. Seung-Taik: Antioxidant and anticancer activities of organic extracts from Platycodon grandiflorum A. De Candolle roots. J. Ethnopharmacol., 93, 409-415 (2004).
    • (2004) J. Ethnopharmacol , vol.93 , pp. 409-415
    • Ji-Young, L.1    Woo-Ik, H.2    Seung-Taik, L.3
  • 16
    • 5444235314 scopus 로고    scopus 로고
    • Effect of aging on liver functions - An experimental study in a perfused rat liver model
    • Jourdana, M., M. Vaubourdolleb, C.L. Cynobera and C. Aussel: Effect of aging on liver functions - An experimental study in a perfused rat liver model. Exper. Geront., 39, 1341-1346 (2004).
    • (2004) Exper. Geront , vol.39 , pp. 1341-1346
    • Jourdana, M.1    Vaubourdolleb, M.2    Cynobera, C.L.3    Aussel, C.4
  • 17
    • 77049204706 scopus 로고
    • A note on the spectrophotometric assay of glutamic-oxalacetic transaminase in human blood
    • Karmen, A.: A note on the spectrophotometric assay of glutamic-oxalacetic transaminase in human blood. J. Cli. Invest., 34, 131-133 (1955).
    • (1955) J. Cli. Invest , vol.34 , pp. 131-133
    • Karmen, A.1
  • 18
    • 0029093470 scopus 로고
    • Immunohistochemical evidence of neuronal and glial differentiation in retinoblastomas
    • KePing, X., L. Shang Lian and N. Chuo: Immunohistochemical evidence of neuronal and glial differentiation in retinoblastomas. Brit. J. Opthal., 79, 771-776 (1995).
    • (1995) Brit. J. Opthal , vol.79 , pp. 771-776
    • KePing, X.1    Shang Lian, L.2    Chuo, N.3
  • 19
    • 1642505512 scopus 로고    scopus 로고
    • Antioxidant enzymes and lipid peroxidation indifferent stages of breast cancer
    • Khanzode, S.S., M.G. Muddeshwar, S.D. Khanzode and G.N. Dakhale: Antioxidant enzymes and lipid peroxidation indifferent stages of breast cancer. Free Rad. Res., 38, 81-85 (2004).
    • (2004) Free Rad. Res , vol.38 , pp. 81-85
    • Khanzode, S.S.1    Muddeshwar, M.G.2    Khanzode, S.D.3    Dakhale, G.N.4
  • 20
    • 0033057371 scopus 로고    scopus 로고
    • Thioureas differentially induce rat hepatic microsomal epoxide hydrolase and rGSTA2 irrespective of their oxygen radical scavenging effect: Effects on toxicant-induced liver injury
    • Kim, S.G., H.J. Kim and C.H. Yang: Thioureas differentially induce rat hepatic microsomal epoxide hydrolase and rGSTA2 irrespective of their oxygen radical scavenging effect: Effects on toxicant-induced liver injury. Chemico-Biol. Inter., 117, 117-134 (1999).
    • (1999) Chemico-Biol. Inter , vol.117 , pp. 117-134
    • Kim, S.G.1    Kim, H.J.2    Yang, C.H.3
  • 21
    • 0021125391 scopus 로고
    • Increased biliary GSSG effleux from rats livers perfused with thiocarbamide substrates for the flavin-contining monooxygenase
    • Krieter, P.A., D.M. Ziegler, K.E. Hill and R.F. Burk: Increased biliary GSSG effleux from rats livers perfused with thiocarbamide substrates for the flavin-contining monooxygenase. Mole. Pharmacol., 26, 122-127 (1984).
    • (1984) Mole. Pharmacol , vol.26 , pp. 122-127
    • Krieter, P.A.1    Ziegler, D.M.2    Hill, K.E.3    Burk, R.F.4
  • 23
    • 0029451744 scopus 로고
    • Radioprotective effect of α-carboline and its carboline analogues
    • Li, G.W., P.G. Liang and G.Y. Pan: Radioprotective effect of α-carboline and its carboline analogues. Acta Pharmacol. Sinica., 30, 715-717 (1995).
    • (1995) Acta Pharmacol. Sinica , vol.30 , pp. 715-717
    • Li, G.W.1    Liang, P.G.2    Pan, G.Y.3
  • 25
    • 3343003791 scopus 로고    scopus 로고
    • Vegetables, fruit consumption and risk of lung cancer among middle-aged Japanese men and women: JPHC study
    • Liu, Y., T. Sobue, T. Otani and S. Tsugane: Vegetables, fruit consumption and risk of lung cancer among middle-aged Japanese men and women: JPHC study. Cancer Causes and Control, 15, 349-357 (2004).
    • (2004) Cancer Causes and Control , vol.15 , pp. 349-357
    • Liu, Y.1    Sobue, T.2    Otani, T.3    Tsugane, S.4
  • 26
    • 0024378635 scopus 로고
    • Neuron-specific enolase: A marker for malignant melanoma
    • Lorenz, J. and W. Dippold: Neuron-specific enolase: A marker for malignant melanoma. J. Nat. Cancer Inst., 8, 1754-1755 (1989).
    • (1989) J. Nat. Cancer Inst , vol.8 , pp. 1754-1755
    • Lorenz, J.1    Dippold, W.2
  • 27
    • 0031728889 scopus 로고    scopus 로고
    • Serum S-100 and neuron-specific enolase for prediction of regaining consciousness after global cerebral ischemia
    • Martens, P., A. Raabe and P. Johnsson: Serum S-100 and neuron-specific enolase for prediction of regaining consciousness after global cerebral ischemia. Amer. Heart Asso., 29, 2363-2366 (1998).
    • (1998) Amer. Heart Asso , vol.29 , pp. 2363-2366
    • Martens, P.1    Raabe, A.2    Johnsson, P.3
  • 29
    • 3042686779 scopus 로고    scopus 로고
    • Interventions with antioxidants and nutrients in relation to oxidative DNA damage and repair
    • Moller, P. and S. Loft. Interventions with antioxidants and nutrients in relation to oxidative DNA damage and repair. Mut Res., 551, 79-89 (2004).
    • (2004) Mut Res , vol.551 , pp. 79-89
    • Moller, P.1    Loft, S.2
  • 30
    • 0000087642 scopus 로고
    • The determination of bilirubin with the photoelectric colorimeter
    • Molly, H. and K. Evelyn.: The determination of bilirubin with the photoelectric colorimeter. J. Biol. Chem., 119, 481-490 (1937).
    • (1937) J. Biol. Chem , vol.119 , pp. 481-490
    • Molly, H.1    Evelyn, K.2
  • 31
    • 0034096273 scopus 로고    scopus 로고
    • The antioxidant/anticancer potentiel of phenolics compounds isolated from olive oil
    • Owen, R., A. Giacosa, W.E. Hull, R. Haubner, B. Spiegeehalder and H. Bartsch: The antioxidant/anticancer potentiel of phenolics compounds isolated from olive oil. Eur. J. Cancer, 36, 1235-1247 (2000).
    • (2000) Eur. J. Cancer , vol.36 , pp. 1235-1247
    • Owen, R.1    Giacosa, A.2    Hull, W.E.3    Haubner, R.4    Spiegeehalder, B.5    Bartsch, H.6
  • 32
    • 0343465395 scopus 로고    scopus 로고
    • Studies on the pharmacological action of the total alkaloid of Peganum harmala
    • Pan, Q.C., X.P. Yang and C.J. Li: Studies on the pharmacological action of the total alkaloid of Peganum harmala. Acad. J. Sums., 18, 165-167 (1997).
    • (1997) Acad. J. Sums , vol.18 , pp. 165-167
    • Pan, Q.C.1    Yang, X.P.2    Li, C.J.3
  • 33
    • 3142554408 scopus 로고    scopus 로고
    • Diet composition and the risk of type 2 diabetes: Epidemiological and clinical evidence
    • Parillo, M. and G. Riccardi: Diet composition and the risk of type 2 diabetes: Epidemiological and clinical evidence. Brit. J. Nutr., 92, 7-19 (2004).
    • (2004) Brit. J. Nutr , vol.92 , pp. 7-19
    • Parillo, M.1    Riccardi, G.2
  • 34
    • 1442274747 scopus 로고    scopus 로고
    • Comparative cytotoxicity of N-substituted N-(4-imidazole-ethyl) thiourea in precision-cut rat liver slices
    • Rob, C.A.O., N.M.C. Jan and P.E.V. Nico: Comparative cytotoxicity of N-substituted N-(4-imidazole-ethyl) thiourea in precision-cut rat liver slices. Toxicology, 197, 81-91 (2004).
    • (2004) Toxicology , vol.197 , pp. 81-91
    • Rob, C.A.O.1    Jan, N.M.C.2    Nico, P.E.V.3
  • 35
  • 36
    • 0033376510 scopus 로고    scopus 로고
    • Evaluation of hepatoprotective efficacy of APCL-A polyherbal formulation in vivo in rats
    • Shahani, S.: Evaluation of hepatoprotective efficacy of APCL-A polyherbal formulation in vivo in rats. Indian Drugs, 36, 628-631 (1999).
    • (1999) Indian Drugs , vol.36 , pp. 628-631
    • Shahani, S.1
  • 37
    • 0036234519 scopus 로고    scopus 로고
    • An In vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its a-Carboline alkaloids
    • Sobhani, A.M., S.A. Ebrahimi and M. Mahmoudian: An In vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its a-Carboline alkaloids. J. Phar. Pharmac. Sci., 5, 19-23 (2000).
    • (2000) J. Phar. Pharmac. Sci , vol.5 , pp. 19-23
    • Sobhani, A.M.1    Ebrahimi, S.A.2    Mahmoudian, M.3
  • 38
    • 1542380511 scopus 로고    scopus 로고
    • Diet, nutrition and the prevention of hypertension and cardiovascular diseases
    • Srinath, R.K. and M.B. Katan: Diet, nutrition and the prevention of hypertension and cardiovascular diseases. Pub. Hlth. Nut., 7, 167-186 (2004).
    • (2004) Pub. Hlth. Nut , vol.7 , pp. 167-186
    • Srinath, R.K.1    Katan, M.B.2
  • 40
    • 46149138568 scopus 로고
    • Antioxidant activity of flavonoids and reactivity with peroxy radical
    • Torel, J., J. Cillard and P. Cillard: Antioxidant activity of flavonoids and reactivity with peroxy radical. Phytochemistry, 25, 383-385 (1986).
    • (1986) Phytochemistry , vol.25 , pp. 383-385
    • Torel, J.1    Cillard, J.2    Cillard, P.3
  • 41
    • 0025912665 scopus 로고
    • Antioxidative properties of harmane and b-carboline alkaloids
    • Tse, S.Y.H., I.T. Mak and B.F. Dickens: Antioxidative properties of harmane and b-carboline alkaloids. Biochem. Pharmacol., 42, 459-464 (1991).
    • (1991) Biochem. Pharmacol , vol.42 , pp. 459-464
    • Tse, S.Y.H.1    Mak, I.T.2    Dickens, B.F.3
  • 42
    • 1042287039 scopus 로고    scopus 로고
    • Dietary compounds prevent oxidative damage and nitric oxide production by cells involved in demyelinating disease
    • Van Meeteren, M.E., J.J. Hendriks, C.D. Dijkstra and E.A. Van Tol: Dietary compounds prevent oxidative damage and nitric oxide production by cells involved in demyelinating disease. Biochem. Pharmacol., 67, 967-975 (2004).
    • (2004) Biochem. Pharmacol , vol.67 , pp. 967-975
    • Van Meeteren, M.E.1    Hendriks, J.J.2    Dijkstra, C.D.3    Van Tol, E.A.4
  • 43
    • 0024208768 scopus 로고
    • Serum neuron-specific enolase/ neuronal enolase ratio in the diagnosis of neuroblastomas
    • Viallard, J.L., F. Tiget, O. Hartmann, J. Lemerle, F. Demeocq, G. Malpuech and B. Dastugue: Serum neuron-specific enolase/ neuronal enolase ratio in the diagnosis of neuroblastomas. Cancer, 62, 2546-2553 (1988).
    • (1988) Cancer , vol.62 , pp. 2546-2553
    • Viallard, J.L.1    Tiget, F.2    Hartmann, O.3    Lemerle, J.4    Demeocq, F.5    Malpuech, G.6    Dastugue, B.7
  • 45
    • 78651031427 scopus 로고
    • Serum glutamic-pyruvic transaminase in cardiac hepatic disease
    • Wroblewski, F. and J.S. LaDue: Serum glutamic-pyruvic transaminase in cardiac hepatic disease. Proc. Soc. Expe. Biol. Med., 91, 569 (1956).
    • (1956) Proc. Soc. Expe. Biol. Med , vol.91 , pp. 569
    • Wroblewski, F.1    LaDue, J.S.2
  • 46
    • 0038493572 scopus 로고    scopus 로고
    • Inhibitory effect of red koji extracts on mushroom tyrosinase
    • Wu, L.C., Y.C. Chen, J.A. Ho and C.S. Yang: Inhibitory effect of red koji extracts on mushroom tyrosinase. J. Agric. Food Chem., 51, 4240-4246 (2003).
    • (2003) J. Agric. Food Chem , vol.51 , pp. 4240-4246
    • Wu, L.C.1    Chen, Y.C.2    Ho, J.A.3    Yang, C.S.4
  • 47
    • 0024565751 scopus 로고
    • The effect of age upon liver volume and apparent liver blood flow in healthy man
    • Wynne, H.A., L.H. Cope, E. Mutch, M.D. Rawlins, K.W. Woodhouse and O.F. James: The effect of age upon liver volume and apparent liver blood flow in healthy man. Hepatology, 9, 297-301 (1989).
    • (1989) Hepatology , vol.9 , pp. 297-301
    • Wynne, H.A.1    Cope, L.H.2    Mutch, E.3    Rawlins, M.D.4    Woodhouse, K.W.5    James, O.F.6
  • 49
    • 0034928799 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis by dietary polyphenolic compounds
    • Yan, C.S., J.M. Landau, M.T. Huang and H.L. Newark: Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu. Rev. Nutr., 21, 381-406 (2001).
    • (2001) Annu. Rev. Nutr , vol.21 , pp. 381-406
    • Yan, C.S.1    Landau, J.M.2    Huang, M.T.3    Newark, H.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.