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Volumn 117, Issue 2, 1999, Pages 117-134

Thioureas differentially induce rat hepatic microsomal epoxide hydrolase and rGSTA2 irrespective of their oxygen radical scavenging effect: Effects on toxicant-induced liver injury

Author keywords

Cytochrome P450; Diethylthiourea; Dimethylthiourea; Diphenylthiourea; Glutathione S transferase; Microsomal epoxide hydrolase; Tetramethylthiourea

Indexed keywords

BENZENE DERIVATIVE; CARBON TETRACHLORIDE; CYTOCHROME P450; DIMETHYLTHIOUREA; EPOXIDE HYDROLASE; GLUTATHIONE TRANSFERASE; MESSENGER RNA; OXYGEN RADICAL; SCAVENGER; THIOUREA DERIVATIVE;

EID: 0033057371     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(98)00101-X     Document Type: Article
Times cited : (17)

References (32)
  • 1
    • 0029561598 scopus 로고
    • The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to chemoprotection and drug resistance
    • Hayes J.D., Pulford D.J. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to chemoprotection and drug resistance. Crit. Rev. Biochem. Mol. Biol. 30:1995;445-600.
    • (1995) Crit. Rev. Biochem. Mol. Biol. , vol.30 , pp. 445-600
    • Hayes, J.D.1    Pulford, D.J.2
  • 2
    • 0027318721 scopus 로고
    • Glutathione S-transferases: Gene structure and regulation of expression
    • Daniel V. Glutathione S-transferases: gene structure and regulation of expression. Crit. Rev. Biochem. Mol. Biol. 28:1993;173-207.
    • (1993) Crit. Rev. Biochem. Mol. Biol. , vol.28 , pp. 173-207
    • Daniel, V.1
  • 3
    • 0023506857 scopus 로고
    • The effects of selenium and copper deficiencies on glutathione S-transferase and glutathione peroxidase in rat liver
    • J.R. Arthur, P.C. Morrice, F. Nocol, S.E. Beddows, R. Boyd, J.D. Hayes, G.J. Beckett, The effects of selenium and copper deficiencies on glutathione S-transferase and glutathione peroxidase in rat liver, Biochem. J. 248 (1987) 539-544.
    • (1987) Biochem. J. , vol.248 , pp. 539-544
    • Arthur, J.R.1    Morrice, P.C.2    Nocol, F.3    Beddows, S.E.4    Boyd, R.5    Hayes, J.D.6    Beckett, G.J.7
  • 4
    • 0028171293 scopus 로고
    • 2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response
    • 2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response. Cell. 79:1994;583-593.
    • (1994) Cell , vol.79 , pp. 583-593
    • Levine, A.1    Tenhaken, R.2    Dixon, R.3    Lamb, C.4
  • 5
    • 0030474051 scopus 로고    scopus 로고
    • Thiol regulation of endotoxin-induced release of tumour necrosis factor alpha from isolated rat Kupffer cells
    • Neuschwander-Tetri B.A., Bellezzo J.M., Britton R.S., Bacon B.R., Fox E.S. Thiol regulation of endotoxin-induced release of tumour necrosis factor alpha from isolated rat Kupffer cells. Biochem. J. 320:1996;1005-1010.
    • (1996) Biochem. J. , vol.320 , pp. 1005-1010
    • Neuschwander-Tetri, B.A.1    Bellezzo, J.M.2    Britton, R.S.3    Bacon, B.R.4    Fox, E.S.5
  • 6
    • 0025852479 scopus 로고
    • Modulation of transcription factor NF-κB binding activity by oxidation-reduction in vitro
    • Toledano M.B., Leonard W.J. Modulation of transcription factor NF-κB binding activity by oxidation-reduction in vitro. Proc. Natl. Acad. Sci. 88:1991;4328-4332.
    • (1991) Proc. Natl. Acad. Sci. , vol.88 , pp. 4328-4332
    • Toledano, M.B.1    Leonard, W.J.2
  • 7
    • 0029990552 scopus 로고    scopus 로고
    • Role of oxidants and antioxidants in the induction of AP-1, NF-κB and glutathione S-transferase gene expression
    • Pinkus R., Weiner L.M., Daniel V. Role of oxidants and antioxidants in the induction of AP-1, NF-κB and glutathione S-transferase gene expression. J. Biol. Chem. 271:1996;13422-13429.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13422-13429
    • Pinkus, R.1    Weiner, L.M.2    Daniel, V.3
  • 8
    • 0030600582 scopus 로고    scopus 로고
    • Expression of glutathione S-transferases Ya, Yb1, Yb2, Yc1 and Yc2 and microsomal epoxide hydrolase gene by thiazole, benzothiazole and benzothiadiazole
    • Kim S.G., Cho M.K. Expression of glutathione S-transferases Ya, Yb1, Yb2, Yc1 and Yc2 and microsomal epoxide hydrolase gene by thiazole, benzothiazole and benzothiadiazole. Biochem. Pharmacol. 52:1996;1831-1841.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 1831-1841
    • Kim, S.G.1    Cho, M.K.2
  • 9
    • 0027936825 scopus 로고
    • Differential expression of microsomal epoxide hydrolase gene by azole heterocycles in rat
    • Kim S.G., Jung K.H., Yang W.K., Kim N.D. Differential expression of microsomal epoxide hydrolase gene by azole heterocycles in rat. Biochem. Pharmacol. 48:1994;111-120.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 111-120
    • Kim, S.G.1    Jung, K.H.2    Yang, W.K.3    Kim, N.D.4
  • 10
    • 0027281897 scopus 로고
    • Induction of rat liver microsomal epoxide hydrolase by thiazole and pyrazine: Hydrolysis of 2-cyanoethylene oxide
    • Kim S.G., Kedderis G.L., Batra R., Novak R.F. Induction of rat liver microsomal epoxide hydrolase by thiazole and pyrazine: hydrolysis of 2-cyanoethylene oxide. Carcinogenesis. 14:1993;1665-1670.
    • (1993) Carcinogenesis , vol.14 , pp. 1665-1670
    • Kim, S.G.1    Kedderis, G.L.2    Batra, R.3    Novak, R.F.4
  • 11
    • 0017124902 scopus 로고
    • Studies on the mechanism of toxicity and of development of tolerance to pulmonary toxin, alpha-naphthyl thiourea
    • Boyd M.R., Neal R.A. Studies on the mechanism of toxicity and of development of tolerance to pulmonary toxin, alpha-naphthyl thiourea. Drug Metab. Dispos. 4:1976;314-322.
    • (1976) Drug Metab. Dispos. , vol.4 , pp. 314-322
    • Boyd, M.R.1    Neal, R.A.2
  • 12
    • 0001255753 scopus 로고
    • Liver tumors in rats fed thiourea or thioacetamide
    • Fitzhugh O.G., Nelson A.A. Liver tumors in rats fed thiourea or thioacetamide. Science. 108:1948;626-628.
    • (1948) Science , vol.108 , pp. 626-628
    • Fitzhugh, O.G.1    Nelson, A.A.2
  • 13
    • 0023223364 scopus 로고
    • The specificity of thiourea, dimethylthiourea and dimethylsuphoxide as scavengers of hydroxyl radicals
    • Mohammad W., Barry H., Martin G., Christoper P.M., Duncan C.S.H., Harold B. The specificity of thiourea, dimethylthiourea and dimethylsuphoxide as scavengers of hydroxyl radicals. Biochem. J. 243:1987;867-870.
    • (1987) Biochem. J. , vol.243 , pp. 867-870
    • Mohammad, W.1    Barry, H.2    Martin, G.3    Christoper, P.M.4    Duncan, C.S.H.5    Harold, B.6
  • 14
    • 0025137028 scopus 로고
    • Thioureas react with superoxide radicals to yield a sulfhydryl compound: Explanation for protective effect against paraquat
    • Kelner M.J., Bagnell R., Welch K.J. Thioureas react with superoxide radicals to yield a sulfhydryl compound: explanation for protective effect against paraquat. J. Biol. Chem. 265:1990;1306-1311.
    • (1990) J. Biol. Chem. , vol.265 , pp. 1306-1311
    • Kelner, M.J.1    Bagnell, R.2    Welch, K.J.3
  • 15
    • 0031126944 scopus 로고    scopus 로고
    • Dimethylthiourea protects against gram-negative sepsis and decreases tumor necrosis factor and nuclear factor kappa B activity
    • Sprong R.C., Aarsman C.J., van Oirschot J.F., van Asbeck B.S. Dimethylthiourea protects against gram-negative sepsis and decreases tumor necrosis factor and nuclear factor kappa B activity. J. Lab. Clin. Med. 129:1997;470-481.
    • (1997) J. Lab. Clin. Med. , vol.129 , pp. 470-481
    • Sprong, R.C.1    Aarsman, C.J.2    Van Oirschot, J.F.3    Van Asbeck, B.S.4
  • 16
    • 0025183258 scopus 로고
    • The role of P450IIE1 in the metabolism of 3-hydroxypyridine, a constituent of tabacco smoke: Redox cycling and DNA strand scission by the metabolite 2,5-dihydroxypyridine
    • Kim S.G., Novak R.F. The role of P450IIE1 in the metabolism of 3-hydroxypyridine, a constituent of tabacco smoke: redox cycling and DNA strand scission by the metabolite 2,5-dihydroxypyridine. Cancer Res. 50:1990;5333-5339.
    • (1990) Cancer Res. , vol.50 , pp. 5333-5339
    • Kim, S.G.1    Novak, R.F.2
  • 17
    • 0024547417 scopus 로고
    • Human DNA damage induced by 1,2,4-benzenetriol, a benzene metabolite
    • Kawanishi S., Inoue S., Kawanishi M. Human DNA damage induced by 1,2,4-benzenetriol, a benzene metabolite. Cancer Res. 49:1989;164-168.
    • (1989) Cancer Res. , vol.49 , pp. 164-168
    • Kawanishi, S.1    Inoue, S.2    Kawanishi, M.3
  • 19
    • 0027325387 scopus 로고
    • The induction of cytochrome P450 2E1 by nitrogen- And sulfur-containing heterocycles: Expression and molecular regulation
    • Kim S.G., Novak R.F. The induction of cytochrome P450 2E1 by nitrogen- and sulfur-containing heterocycles: expression and molecular regulation. Toxicol. Appl. Pharmacol. 120:1993;257-265.
    • (1993) Toxicol. Appl. Pharmacol. , vol.120 , pp. 257-265
    • Kim, S.G.1    Novak, R.F.2
  • 20
    • 0025137467 scopus 로고
    • An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Puissant C., Houdebine L.-M. An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Biotechniques. 8:1990;148-149.
    • (1990) Biotechniques , vol.8 , pp. 148-149
    • Puissant, C.1    Houdebine, L.-M.2
  • 21
    • 0027050428 scopus 로고
    • Transcriptional regulation of rat microsomal epoxide hydrolase gene by antimycotic agents
    • Kim S.G. Transcriptional regulation of rat microsomal epoxide hydrolase gene by antimycotic agents. Mol. Pharmacol. 42:1992;273-279.
    • (1992) Mol. Pharmacol. , vol.42 , pp. 273-279
    • Kim, S.G.1
  • 22
    • 0021368690 scopus 로고
    • Rat liver glutathione S-transferases: Complete nucleotide sequence of a glutathione S-transferases mRNA and the regulation of the Ya, Yb and Yc mRNAs by 3-methylcholanthrene and phenobarbital
    • Pickett C.B., Telakowski-Hopkins C.A., -F. Ding G.J., Argenbright L., Lu A.Y.H. Rat liver glutathione S-transferases: complete nucleotide sequence of a glutathione S-transferases mRNA and the regulation of the Ya, Yb and Yc mRNAs by 3-methylcholanthrene and phenobarbital. J. Biol. Chem. 259:1984;5182-5188.
    • (1984) J. Biol. Chem. , vol.259 , pp. 5182-5188
    • Pickett, C.B.1    Telakowski-Hopkins, C.A.2    Ding, G.J.-F.3    Argenbright, L.4    Lu, A.Y.H.5
  • 23
    • 0019167355 scopus 로고
    • Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
    • Griffith O.W. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal. Biochem. 106:1980;207-212.
    • (1980) Anal. Biochem. , vol.106 , pp. 207-212
    • Griffith, O.W.1
  • 25
    • 0030604292 scopus 로고    scopus 로고
    • Carbon tetrachoride: Genetic effects and other modes of action
    • McGregor D., Lang M. Carbon tetrachoride: genetic effects and other modes of action. Mutation Res. 366:1996;181-195.
    • (1996) Mutation Res. , vol.366 , pp. 181-195
    • McGregor, D.1    Lang, M.2
  • 27
    • 0021688414 scopus 로고
    • Prevention of granulocyte-mediated oxidant lung in rats by a hydroxyl radical scavenger, dimethylthiourea
    • Fox R.B. Prevention of granulocyte-mediated oxidant lung in rats by a hydroxyl radical scavenger, dimethylthiourea. J. Clin. Invest. 74:1984;1456-1464.
    • (1984) J. Clin. Invest. , vol.74 , pp. 1456-1464
    • Fox, R.B.1
  • 28
    • 0242320651 scopus 로고
    • Malignant tumors in the eyelids and auricular region of thiourea-treated rats
    • A. Rosin, H. Ungar, Malignant tumors in the eyelids and auricular region of thiourea-treated rats, Cancer Res. 17 (1957) 302-305.
    • (1957) Cancer Res. , vol.17 , pp. 302-305
    • Rosin, A.1    Ungar, H.2
  • 29
    • 0018642835 scopus 로고
    • S-oxygenation N-substituted thioureas catalyzed by the pig liver microsomal FAD-containing monooxygenase
    • Poulsen L.L., Hyslop R.M., Ziegler D.M. S-oxygenation N-substituted thioureas catalyzed by the pig liver microsomal FAD-containing monooxygenase. Arch. Biochem. Biophys. 198:1979;78-88.
    • (1979) Arch. Biochem. Biophys. , vol.198 , pp. 78-88
    • Poulsen, L.L.1    Hyslop, R.M.2    Ziegler, D.M.3
  • 30
    • 0022502928 scopus 로고
    • Dimethylthiourea decreases acute lung edema in phorbol myristate acetate-treated rabbits
    • Jackson J.H., White C.W., McMurtry I.F., Berger E.M., Repine J.E. Dimethylthiourea decreases acute lung edema in phorbol myristate acetate-treated rabbits. J. Appl. Physiol. 61:1986;353-360.
    • (1986) J. Appl. Physiol. , vol.61 , pp. 353-360
    • Jackson, J.H.1    White, C.W.2    McMurtry, I.F.3    Berger, E.M.4    Repine, J.E.5
  • 31
    • 0030951561 scopus 로고    scopus 로고
    • Induction of hepatic heme oxygenase and changes in cytochrome P450s in response to oxidative stress produced by stilbenes and stilbene oxides in rats
    • Oguro T., Kaneko E., Numazawa S., Imaoka S., Funae Y., Yoshida T. Induction of hepatic heme oxygenase and changes in cytochrome P450s in response to oxidative stress produced by stilbenes and stilbene oxides in rats. J. Pharmacol. Exp. Ther. 280:1997;1455-1462.
    • (1997) J. Pharmacol. Exp. Ther. , vol.280 , pp. 1455-1462
    • Oguro, T.1    Kaneko, E.2    Numazawa, S.3    Imaoka, S.4    Funae, Y.5    Yoshida, T.6
  • 32
    • 0031426310 scopus 로고    scopus 로고
    • Alkylating of cellular macromolecules and target specificity of carcinogenic nitrodialkylamines: Metabolic activation by cytochromes P450 2B1 and 2E1
    • Shu L., Hollenberg P.F. Alkylating of cellular macromolecules and target specificity of carcinogenic nitrodialkylamines: Metabolic activation by cytochromes P450 2B1 and 2E1. Carcinogenesis. 18:1997;801-810.
    • (1997) Carcinogenesis , vol.18 , pp. 801-810
    • Shu, L.1    Hollenberg, P.F.2


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