Biology of thioredoxin and its association with Alzheimer's disease and Parkinson's disease

Yaoxue Xuebao

Volumn 43, Issue 1, 2008, Pages 1-8

  Li, Li Bo ^a   Liu, Geng Tao ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Alzheimer's disease; Biology; Parkinson's disease; Thioredoxin

Indexed keywords

ANTIOXIDANT; NEUROPROTECTIVE AGENT; THIOREDOXIN;

ALZHEIMER DISEASE; ANIMAL; APOPTOSIS; DRUG EFFECT; HUMAN; METABOLISM; OXIDATION REDUCTION REACTION; PARKINSON DISEASE; PHYSIOLOGY; REVIEW;

ALZHEIMER DISEASE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; HUMANS; NEUROPROTECTIVE AGENTS; OXIDATION-REDUCTION; PARKINSON DISEASE; THIOREDOXINS;

EID: 38849111345     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (48)

1. Nakamura H. Thioredoxin and its related molecules: update 2005 [J]. Antioxid Redox Signal, 2005, 7:823-828.
2. Lillig CH, Holmgren A. Thioredoxin and related molecules - from biology to health and disease [J]. Antioxid Redox Signal, 2007, 9:25-47.
3. Pekkari K, Holmgren A. Truncated thioredoxin: physiological functions and mechanism [J]. Antioxid Redox Signal, 2004, 6:53-61.
4. Yoshioka J, Schreiter ER, Lee RT. Role of thioredoxin in cell growth through interactions with signaling molecules [J]. Antioxid Redox Signal, 2006, 8:2143-2151.
5. Tagaya Y, Maeda Y, Mitsui A, et al. ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction [J]. EMBO J, 1989, 8:757 -764. Erratum in: EMBO J, 1994, 13:2244.
6. Sadek CM, Jimenez A, Damdimopoulos AE, et al. Characterization of human thioredoxin-like 2. A novel microtubule-binding thioredoxin expressed predominantly in the cilia of lung airway epithelium and spermatid manchette and axoneme [J]. J Biol Chem, 2003, 278: 13133-13142.
7. Arner ES, Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase [J]. Eur J Biochem, 2000, 267:6102-6109.
8. Gromer S, Urig S, Becker K. The thioredoxin system-from science to clinic [J]. Med Res Rev, 2004, 24:40-89.
9. Kaimul AM, Nakamura H, Masutani H, et al. Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome [J]. Free Radic Biol Med, 2007, 43:861-868.
10. Kanzok SM, Fechner A, Bauer H, et al. Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster [J]. Science, 2001, 291:643-646.
11. Yoshida T, Oka S, Masutani H, et al. The role of thioredoxin in the aging process: involvement of oxidative stress [J]. Antioxid Redox Signal, 2003, 5:563-570.
12. Yoshida T, Nakamura H, Masutani H, et al. The involvement of thioredoxin and thioredoxin binding protein-2 on cellular proliferation and aging process [J]. Ann N Y Acad Sci, 2005, 1055:1-12.
13. Stadtman ER, Van Remmen H, Richardson A, et al. Methionine oxidation and aging [J]. Biochim Biophys Acta, 2005, 1703:135-140.
14. Trigona WL, Mullarky IK, Cao Y, et al. Thioredoxin reductase regulates the induction of haem oxygenase-1 expression in aortic endothelial cells [J]. Biochem J, 2006, 394:207-216.
15. Hirota K, Nakamura H, Masutani H, et al. Thioredoxin superfamily and thioredoxin-inducing agents [J]. Ann N Y Acad Sci, 2002, 957:189-199.
16. Powis G, Montfort WR. Properties and biological activities of thioredoxins [J]. Annu Rev Pharmacol Toxicol, 2001, 41:261-295.
17. Saitoh M, Nishitoh H, Fujii M, et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1 [J]. EMBOJ, 1998, 17: 2596-2606.
18. Biaglow JE, Miller RA. The thioredoxin reductase/thioredoxin system: novel redox targets for cancer therapy [J]. Cancer Biol Ther, 2005, 4:6-13.
19. 3 upregulated protein 1 (VDUP1) is a regulator for redox signaling and stress-mediated diseases [J]. J Dermatol, 2006, 33:662-669.
20. Kabe, Y, Ando K, Hirao S, et al. Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus [J]. Antioxid Redox Signal, 2005, 7:395-403.
21. Kobayashi-Miura M, Shioji K, Hoshino Y, et al. Oxygen sensing and redox signaling: the role of thioredoxin in embryonic development and cardiac diseases [J]. Am J Physiol Heart Cire Physiol, 2007, 292:112040-2050.
22. Tanaka T, Hosoi F, Yamaguchi-Iwai Y, et al. Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis [J]. EMBO J, 2002, 21:1695-1703.
23. Nonn L, Williams RR, Erickson RP, et al. The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice [J]. Mol Cell Biol, 2003, 23:916-922.
24. Miranda-Vizuete A, Ljung J, Damdimopoulos AK, et al. Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa [J]. J Biol Chem, 2001, 276:31567-31574.
25. Calabrese V, Guagliano E, Sapienza M, et al. Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vilagenes [J]. Neurochem Res, 2007, 32:757-773.
26. Lovell MA, Xie C, Gabbita SP, et al. Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain [J]. Free Radic Biol Med. 2000, 28:418-427.
27. Takagi Y, Hattori I, Nozaki K, et al. Excitotoxic hippocampal injury is attenuated in thioredoxin transgenic mice [J]. J Cereb Blood Flow Metab, 2000, 20:829-833.
28. Akterin S, Cowburn RF, Miranda-Vizuete A, et al. Involvement of glutaredoxin-1 and thioredoxin-1 in beta-amyloid toxicity and Alzheimer's disease [J]. Cell Death Differ, 2006, 13:1454-1465.
29. Masutani H, Bai J, Kim YC. et al. Thioredoxin as a neurotrophic cofactor and an important regulator of neuroprotection [J]. Mol Neurobiol, 2004, 29: 229-242.
30. Stadtman ER, Moskovitz J, Levine RL. Oxidation of methionine residues of proteins: biological consequences [J]. Antioxid Redox Signal, 2003, 5:577-582.
31. Chiueh C, Lee S, Andoh T, et al. Induction of antioxidalive and antiapoptolic thioredoxin supports neuroprotective hypothesis of estrogen [J]. Endocrine, 2003, 21:27-31.
32. Cao J, Sun HY, Zhu ZR, et al. Antioxidant effects of dehydroepiandrosterone are related to up-regulation of thioredoxin in SH-SY5Y cells [J]. Acta Biochim Biophys Sin, 2005, 37:119-125.
33. Landino LM, Skreslet TE, Alston JA. Cysteine oxidation of tau and microtubule-associated protein-2 by peroxynitrite: modulation of microtubule assembly kinetics by the thioredoxin reductase system [J]. J Biol Chem, 2004, 279:35101-35105.
34. Qin Y, Gao J, Zhang TT, et al. Changes of thioredoxin mRNA level in neurons insulted by sodium azide [J]. Acta Biol Exp Sin, 2002, 35:26-30.
35. 2 in PC12 cells [J]. Arch Biochem Biophys, 2002, 397:414-423.
36. Bai J, Nakamura H, Hattori I, et al. Thioredoxin suppresses 1-methyl-4-phenylpyridinium-induced neuro-toxicity in rat PC12 cells [J]. Neurosci Lett, 2002, 321: 81-84.
37. Bai J, Nakamura H, Kwon YW, et al. Does thioredoxin-1 prevent mitochondria- and endoplasmic reticulum-mediated neuroloxicity of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine? [J] Antioxid Redox Signal, 2007, 9: 603-608.
38. Hirota K, Nakamura H, Arai T, et al. Geranylgeranylacetone enhances expression of thioredoxin and suppresses ethanol-induced cytotoxicity in cultured hepatocytes [J]. Biochem Biophys Res Commun, 2000, 275:825-830.
39. Dekigai H, Nakamura H, Bai J, et al. Geranylgeranylacetone promotes induction and secretion of thioredoxin in gastric mucosal cells and peripheral blood lymphocytes J]. Free Radic Res, 2001, 35:23-30.
40. Kojima S, Matsuki O, Nomura T, et al. Elevation of antioxidant potency in the brain of mice by low-dose gamma-ray irradiation and its effect on 1-melhyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) induced brain damage [J]. Free Radic Biol Med, 1999, 26:388-395.
41. Feng J. Microtubule: a common target for parkin and Parkinson' s disease toxins [J]. Neuroscientist, 2006, 12:469-476.
42. Andoh T, Chock PB, Chiueh CC. Preconditioning-mediated neuroprotection: role of nitric oxide, cGMP, and new protein expression [J] Ann N Y Acad Sci, 2002, 962:1-7.
43. Andoh T, Chock PB, Chiueh CC. The roles of thioredoxin in protection against oxidative stress-induced apoptosis in SH-SY5Y cells [J]. J Biol Chem, 2002, 277:9655-9660.
44. Joguchi A, Otsuka I, Minagawa S, et al. Overexpression of VDUP1 mRNA sensitizes HeLa cells to paraquat [J]. Biochem Biophys Res Commun, 2002, 293:293-297.
45. Umeda-Kameyama Y, Tsuda M, Ohkura C, et al. Thioredoxin suppresses Parkin-associated endothelin receptor-like receptor-induced neurotoxicity and extends longevity in Drosophila [J]. J Biol Chem, 2007, 282: 11180-11187.
46. Nagatsu T, Sawada M. Molecular mechanism of the relation of monoamine oxidase B and its inhibitors to Parkinson's disease: possible implications of glial cells [J]. J Neural Transm Suppl, 2006, (71):53-65.
47. Andoh T, Chock PB, Murphy DL, et al. Role of the redox protein thioredoxin in cytoprotective mechanism evoked by (-)-deprenyl [J]. Mol Pharmacol, 2005, 68:1408-1414.
48. Uehara T, Nakamura T, Yao D, et al. S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration [J]. Nature, 2006, 441:513-517.