Does thioredoxin-1 prevent mitochondria- and endoplasmic reticulum-mediated neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine?

Antioxidants and Redox Signaling

Volumn 9, Issue 5, 2007, Pages 603-608

  Bai, Jie ^a,b   Nakamura, Hajime ^c   Kwon, Yong Won ^a   Tanito, Masaki ^a   Ueda, Shugo ^c   Tanaka, Toru ^a   Hattori, Itaro ^a   Ban, Sadayuki ^d   Momoi, Takashi ^e   Kitao, Yasuko ^f   Ogawa, Satoshi ^f   Yodoi, Junji ^a  

^a KYOTO UNIVERSITY   (Japan)

^b Kunming University of Science and Technology   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^e NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^f KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ADENOSINE TRIPHOSPHATE; CASPASE 12; MITOCHONDRIAL DNA; THIOREDOXIN; THIOREDOXIN I; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHORT SURVEY; TRANSGENIC MOUSE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; 1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; CELL DEATH; ENDOPLASMIC RETICULUM; HELA CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; NEUROTOXINS; PC12 CELLS; RATS; SIGNAL TRANSDUCTION; THIOREDOXIN;

MUS; MUS MUSCULUS;

EID: 34247118321     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2006.1513     Document Type: Short Survey

References (29)

1. Aridor M and Balch WE. Integration of endoplasmic reticulum signaling in health and disease. Nat Med 5: 745-751, 1999.
2. Bai J, Nakamura H, Hattori I, Tanito M, and Yodoi J. Thioredoxin suppresses 1-methyl-4-phenylpyridinium-induced neurotoxicity in rat PC12 cells. Neurosci Lett 321: 81-84, 2002.
3. Bai J, Nakamura H, Kwon YW, Hattori I, Yamaguchi Y, Kim YC, Kondo N, Oka S, Ueda S, Masutani H, and Yodoi J. Critical roles of thioredoxin in nerve growth factor-mediated signal transduction and neurite outgrowth in PC12 cells. J Neurosci 23: 503-509, 2003.
4. +)-induced cell cycle arrest. J Biol Chem 279: 38710-38714, 2004.
5. Chan P, Di Monte DA, Luo JJ, DeLanney LE, Irwin I, and Langston JW. Rapid ATP loss caused by methamphetamine in the mouse striatum: relationship between energy impairment and dopaminergic neurotoxicity. J Neurochem 62: 2484-2487, 1994.
6. Endoh M, Kunishita T, and Tabira T. Thioredoxin from activated macrophages as a trophic factor for central cholinergic neurons in vitro. Biochem Biophys Res Commun 192: 760-765, 1993.
7. Fujita E, Kouroku Y, Jimbo A, Isoai A, Maruyama K, and Momoi T. Caspase-12 processing and fragment translocation into nuclei of tunicamycin-treated cells. Cell Death Differ 9: 1108-1114, 2002.
8. Hantraye P, Brouillet E, Ferrante R, Palfi S, Dolan R, Matthews RT, and Beal MF. Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons. Nat Med 2: 1017-1021, 1996.
9. Holmgren A. Thioredoxin. Annu Rev Biochem 54: 237-271, 1985.
10. Imai Y, Soda M, Murakami T, Shoji M, Abe K, and Takahashi R. A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. J Biol Chem 278: 51901-51910, 2003.
11. Inazu M, Takeda H, and Matsumiya T. Expression and functional characterization of the extraneuronal monoamine transporter in normal human astrocytes. J Neurochem 84: 43-52, 2003.
12. Inomata Y, Nakamura H, Tanito M, Teratani A, Kawaji T, Kondo N, Yodoi J, and Tanihara H. Thioredoxin inhibits NMDA-induced neurotoxicity in the rat retina. J Neurochem 98: 372-385, 2006.
13. Jankovi J. Parkinsonism. In: Wyngaarden JB, Smith LH, Bennett JC (Eds). Cecil's Textbook of Medicine. Philadelphia: Saunders, 1992, p. 2130-2133.
14. Kitao Y, Ozawa K, Miyazaki M, Tamatani M, Kobayashi T, Yanagi H, Okabe M, Ikawa M, Yamashima T, Stern DM, Hori O, and Ogawa S. Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity. J Clin Invest 108: 1439-1450, 2001.
15. Kondo N, Ishii Y, Kwon YW, Tanito M, Horita H, Nishinaka Y, Nakamura H, and Yodoi J. Redox-sensing release of human thioredoxin from T lymphocytes with negative feedback loops. J Immunol 172: 442-448, 2004.
16. Langston JW and Irwin I. MPTP: current concepts and controversies. Clin Neuropharmacol 9: 485-507, 1986.
17. Matsuo Y, Akiyama N, Nakamura H, Yodoi J, Noda M, and Kizaka-Kondoh S. Identification of a novel thioredoxin-related transmembrane protein. J Biol Chem 276: 10032-10038, 2001.
18. Mattson MP, LaFerla FM, Chan SL, Leissring MA, Shepel PN, and Geiger JD. Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders. Trends Neurosci 23: 222-229, 2000.
19. Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, and Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403: 98-103, 2000.
20. Nakamura H, Matsuda M, Furuke K, Kitaoka Y, Iwata S, Toda K, Inamoto T, Yamaoka Y, Ozawa K, and Yodoi J. Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide. Immunol Lett 42: 75-80, 1994.
21. Nicklas WJ, Vyas I, and Heikkila RE. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Life Sci 36: 2503-2508, 1985.
22. Okuyama H, Nakamura H, Shimahara Y, Uyama N, Kwon YW, Kawada N, Yamaoka Y, and Yodoi J. Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice. J Hepatol 42: 117-123, 2005.
23. Pakkenberg B, Moller A, Gundersen HJ, Mouritzen Dam A, and Pakkenberg H. The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method. J Neurol Neurosurg Psychiatry 54: 30-33, 1991.
24. Przedborski S, Jackson-Lewis V, Yokoyama R, Shibata T, Dawson VL, and Dawson TM. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proc Natl Acad Sci USA 93: 4565-4571, 1996.
25. Przedborski S, Tieu K, Perier C, and Vila M. MPTP as a mitochondrial neurotoxic model of Parkinson's disease. J Bioenerg Biomembr 36: 375-379, 2004.
26. Ryu EJ, Harding HP, Angelastro JM, Vitolo OV, Ron D, and Greene LA. Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. J Neurosci 22: 10690-10698, 2002.
27. Takagi Y, Mitsui A, Nishiyama A, Nozaki K, Sono H, Gon Y, Hashimoto N, and Yodoi J. Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage. Proc Natl Acad Sci USA 96: 4131-4136, 1999.
28. Tanaka T, Hosoi F, Yamaguchi-Iwai Y, Nakamura H, Masutani H, Ueda S, Nishiyama A, Takeda S, Wada H, Spyrou G, and Yodoi J. Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis. EMBO J 21: 1695-1703, 2002.
29. Tanito M, Kwon YW, Kondo N, Bai J, Masutani H, Nakamura H, Fujii J, Ohira A, and Yodoi J. Cytoprotective effects of geranylgeranylacetone against retinal photooxidative damage. J Neurosci 25: 2396-2404, 2005.