Elevation of antioxidant potency in the brain of mice by low-dose γ- ray irradiation and its effect on 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced brain damage

Free Radical Biology and Medicine

Volumn 26, Issue 3-4, 1999, Pages 388-395

  Kojima, Shuji ^a   Matsuki, Osamu ^a   Nomura, Takaharu ^a   Yamaoka, Kiyonori ^b   Takahashi, Marekiyo ^c   Niki, Etsuo ^c  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b Respiratory Center   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Ray; Free radical; Glutathione; Mouse brain; MPTP; Neurodegenerative disorders; Thioredoxin

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ANTIOXIDANT; CATALASE; FREE RADICAL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; SUPEROXIDE DISMUTASE; THIOREDOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN RADIATION; DEGENERATIVE DISEASE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INDUCTION; FEMALE; GAMMA RADIATION; LIPID PEROXIDATION; LOW ENERGY RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE LEVEL;

ANALYSIS OF VARIANCE; ANIMALS; ANTIOXIDANTS; BRAIN; CATALASE; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FREE RADICAL SCAVENGERS; GAMMA RAYS; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MICE; MICE, INBRED C57BL; MPTP POISONING; SUPEROXIDE DISMUTASE; THIOREDOXIN;

ANIMALIA;

EID: 0032953601     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(98)00200-7     Document Type: Article

References (47)

1. Oberly, L. W.; Oberly, T. D. Free radicals, cancer and aging, In: Johnson, J. E. Jr.; Miquel, J., eds. Free radicals, aging and degenerative diseases. New York: Alan R Liss, Inc.; 1986:325-371.
2. Jesberger J.A., Richardson J.S. Oxygen free radicals and brain dysfunction. Int. J. Neurosci. 57:1991;1-7.
3. Simonian N.A., Coyle J.T. Oxidative stress in neurodegenerative disease. Annu. Rev. Pharmacol. Toxicol. 36:1996;83-106.
4. Meister A., Anderson M.E. Glutathione. Ann. Rev. Biochem. 52:1983;611-660.
5. Jain A., Martensson J., Einar E., Auld P.A.M., Meister A. Glutathione deficiency leads to mitochondrial damage in the brain. Proc. Natl. Acad. Sci. USA. 88:1991;1913-1917.
6. Martensson J., Jain A., Stole E., Frayer W., Auld P.A.M., Meister A. Inhibition of glutathione synthesis in the newborn rat; A model of endogenously produced oxidative stress. Proc. Natl. Acad. Sci. USA. 88:1991;9360-9364.
7. Sofic E., Paulus W., Jellinger K., Riederer P., Youdim M.B.H. Selective increase of iron in substantia nigra zona compacta of Parkinson's disease. J. Neurochem. 56:1991;978-982.
8. Dexter D.T., Carayon A., Wells F.R., Javoy-Agid F., Agid Y., Wells F.R., Daniel S.E., Lees A.J., Jenner P., Marsden C.D. Alterations in the levels of iron and ferritin and other trace metals in Parkinson's disease and other neurodegenerative disease affecting the basal ganglia. Brain Res. 114:1991;1953-1975.
9. Jellinger K., Paulus W., Grundke-Iqbal I., Riederer P., Youdim M.B.H. Brain iron and ferritin in Parkinson's disease and Alzheimer's disease. J. Neural Transm. Park. Dis. Dement. Sect. 2:(Austria):1990;327-340.
10. Schapira A.H.V., Cooper J.M., Dexter D.T., Clark J.B., Jenner P., Marsden C.D. Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. 54:1990;823-827.
11. Kojima S., Matsuki O., Kinoshita I., Valdes-Gonzalët T., Shimura N., Kubodera A. Does small-dose γ-ray radiation induce endogenous antioxidant potential in vivo? Biol. Pharm. Bull. 20:1997;601-604.
12. 4-induced liver damage. Anticancer Res. 18:1998;2471-2476.
13. Kojima S., Matsuki O., Nomura T., Kubodera A., Honda Y., Honda S., Tanooka H., Wakasugi K., Yamaoka K. Induction of mRNAs for glutathione-related proteins in mouse liver by low doses of γ-rays. Biochim. Biophys. Acta. 1381:1998;312-318.
14. Langston J.W., Forno L.S., Rebert C.S., Irwin I. Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP) in the squirrel monkey. Brain Res. 292:1984;390-394.
15. Sonsalla P.K., Heikkila R.E. The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice. Eur. J. Pharmacol. 129:1986;339-345.
16. Przedborski S., Kostic V., Jackson-Lewis V., Niani A.B., Simonetti S., Fahn S., Carlson E., Epstein C.J., Cadet J.L. Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. J. Neurosci. 12:1992;1658-1667.
17. +-induced oxygen radical formation with mitochondrial enzymes. Free Radic. Biol. Med. 15:1993;181-186.
18. Singer T.P., Ramsay R.R., Sonsalla P., Nicklas W.J., Heikkila R.E. Biochemical mechanisms underlying MPTP-induced and idiopathic Parkinsonism. New Vista. Adv. Neurol. 60:1993;300-305.
19. Cadet J.L., Ali S.F., Rothman R.B., Epstein C.L. Neurotoxicity, drugs and the Cu, Zn-superoxide dismutase transgenic mice. Mol. Neurobiol. 11:1995;155-163.
20. Sriram K., Pai K.S., Boyd M.R., Ravindranath V. Evidence for generation of oxidative stress in brain by MPTP in vitro and in vivo studies in mice . Brain Res. 749:1997;44-52.
21. Acuna-Castroviejo D., Coto-Montes A., Monti M.G., Ortiz G.S., Reiter R.J. Melatonin is protective against MPTP-induced striatal and hippocampal lesions. Life Sci. 60:1997;23-29.
22. Sedlack J., Lindsay R.H. Estimation of total protein-bound and non-protein sulfhydryl group in tissue with Ellman's reagent. Analyt. Biochem. 25:1968;192-205.
23. Lowry O.H., Rosebrough N.J., Farr A.L., Randall A.L. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 183:1951;265-275.
24. Ohkawa H., Ohishi N., Yagi K. Assay of lipid peroxide in animal tissue by thiobarbituric acid reaction. Analyt. Biochem. 95:1979;351-358.
25. Yamamoto Y., Takahashi K. Glutathione peroxidase isolated from plasma reduces phospholipid hydroperoxide. Arch. Biochem. Biophys. 86:1993;271-278.
26. Oberley, L. W.; Spitz, D. R. Assay of superoxide dismutase activity in tumor tissue. In: Colowick, S. P.; Kaplan, N. O., eds. Methods in enzymology. Acad. Press 105 (ed. Packer, L.), 1984:457-464.
27. Aebi H.I. Catalase. Bergmeyer J., Maraianne G. Methods in enzymatic analyses. vol 3:1983;273-285 Verlag Chemie, Florida.
28. Kitaoka Y., Sorachi K., Nakamura H., Matsutani H., Mitsui A., Kobayashi F., Mori T., Yodoi J. Detection of adult T-cell leukemia-derived factor/human thioredoxin in human serum. Immunol. Lett. 41:1994;155-161.
29. Luthman M., Holmgren A. Rat liver thioredoxin and thioredoxin reductase Purification and characterization . Biochemistry. 21:1982;6628-6633.
30. Collinson L.P., Dawes I.W. Inducibility of the response of yeast cells to peroxide stress. J. Gen. Microbiol. 138:1992;329-335.
31. Flattery-O'Brien J., Collinson L.P., Dawes I.W. Saccharomyces cerevisiae has an inducible response to menadione that differs to that of hydrogen peroxide. J. Gen. Microbiol. 139:1993;501-507.
32. Jamieson D.J. Saccharomyces cerevisiae has distinct adaptive responses to both hydrogen peroxide and menadione. J. Bacteriol. 174:1992;6678-6681.
33. Kimball R.E., Reddy K., Pierce K., Mustafa T.H., Cross C.E. Oxygen toxicity augmentation of antioxidant defense mechanisms in rat lung . Am. J. Physiol. 230:1976;1425-1431.
34. Galiazzo F., Schiesser A., Rotilio G. Glutathione peroxidase in yeast. Presence of the enzyme and induction by oxidative conditions. Biochem. Biophys. Res. Commun. 147:1987;1200-1205.
35. Shiraishi N., Aono K., Utsumi K. Increased metallothionein content in rat liver induced by X-irradiation and exposure to high oxygen tension. Radiat. Res. 95:1983;298-302.
36. Williams R.S., Thomas J.A., Fina M., German Z., Benjamin I.J. Human heat shock protein 70 (hsp 70) protects murine cells from injury during metabolic stress. J. Clin. Invest. 92:1993;503-508.
37. Jamieson D.J., Rivers S.L., Stephen D.W. Analysis of Saccharomyces cerevisiae protein induced by peroxide and superoxide stress. Microbiology. 140:1994;3277-3283.
38. Szekely J.G., Perry K.A., Petkau A. Stimulated responses to lognormally continuous low radiation doses. Health. Phys. 45:1983;699-711.
39. Quintiliani M. The oxygen effect in radiation interaction on DNA and enzymes. Int. J. Radiat. Biol. 50:1986;573-594.
40. Flohë L., Günzler W.A. Glutathione-dependent enzymatic oxido-reduction reaction. Aras I.M., Jakoby W.B. Glutathione metabolism and function . vol. 6:1976;17-34 Raven Press, New York.
41. Lash L.H., Hagen T.M., Jones D.P. Exogenous glutathione protects intestinal epithelial cells from oxidative injury. Proc. Natl. Acad. Sci. USA. 83:1986;4641-4645.
42. Godwin A.K., Meister A., O'Dwyer P.J., Huang C.S., Hamilton T.C., Anderson M.E. High resistance to cisplatin in human ovarian cell lines is associated with marked increase of glutathione synthesis. Proc. Natl. Acad. Sci. USA. 89:1992;3070-3074.
43. Okamoto, T.; Ogiwara, H.; Hayashi, T.; Mitsui, A.; Kawabe, T.; Yodoi, J. Human thioredoxin/adult T cell leukemia-derived factor activates the enhancer binding protein of human immunodeficiency virus type I by thiol redox control mechanism. Int. Immunol. 4:811-819; 1992.©
44. Schenk H.M., Klein W., Erdbrugger W., Drüge W., Schulze-Osthoff K. Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-κB and AP-1. Proc. Natl. Acad. Sci. USA. 91:1994;1672-1676.
45. Xanthoudakis S., Miao G., Pan Y.C., Curran T. Redox activation of fos-jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J. 11:1992;3323-3335.
46. 2 and antioxidant have opposite effects on activation of NF-κB and AP-1 in intact cells AP-1 as secondary antioxidant-responsive factor . EMBO J. 12:1993;2005-2015.
47. Ramsay P.R., McKeown K.A., Johnson E.A., Booth R.G., Singer P. Inhibition of NADH oxidation by pyridine derivatives. Biochem. Biophys. Res. Commun. 146:1987;53-60.