-
2
-
-
0037428498
-
Cyclic GMP-dependent protein kinase regulates the expression of thioredoxin and thioredoxin peroxidase-1 during hormesis in response to oxidative stress-induced apoptosis
-
Andoh T, Chiueh CC, and Chock PB (2003) Cyclic GMP-dependent protein kinase regulates the expression of thioredoxin and thioredoxin peroxidase-1 during hormesis in response to oxidative stress-induced apoptosis. J Biol Chem 278:885-890.
-
(2003)
J Biol Chem
, vol.278
, pp. 885-890
-
-
Andoh, T.1
Chiueh, C.C.2
Chock, P.B.3
-
3
-
-
0036272812
-
Preconditioning-mediated neuroprotection: Role of nitric oxide, cGMP and new protein expression
-
Andoh T, Chock PB, and Chiueh CC (2002a) Preconditioning-mediated neuroprotection: role of nitric oxide, cGMP and new protein expression. Ann NY Acad Sci 962:1-7.
-
(2002)
Ann NY Acad Sci
, vol.962
, pp. 1-7
-
-
Andoh, T.1
Chock, P.B.2
Chiueh, C.C.3
-
4
-
-
0037155817
-
The roles of thioredoxin in protection against oxidative stress-induced apoptosis in SH-SY5Y cells
-
Andoh T, Chock PB, and Chiueh CC (2002b) The roles of thioredoxin in protection against oxidative stress-induced apoptosis in SH-SY5Y cells. J Biol Chem 277:9655-9660.
-
(2002)
J Biol Chem
, vol.277
, pp. 9655-9660
-
-
Andoh, T.1
Chock, P.B.2
Chiueh, C.C.3
-
5
-
-
0030463422
-
Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2′-NH2-MPTP on serotonergic and noradrenergic nerve terminals
-
Andrews AM, Ladenheim B, Epstein CJ, Cadet JL, and Murphy DL (1996) Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2′-NH2-MPTP on serotonergic and noradrenergic nerve terminals. Mol Pharmacol 50:1511-1519.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 1511-1519
-
-
Andrews, A.M.1
Ladenheim, B.2
Epstein, C.J.3
Cadet, J.L.4
Murphy, D.L.5
-
6
-
-
0037087155
-
Thioredoxin suppresses 1-methyl-4-phenylpyridinium-induced neurotoxicity in rat PC12 cells
-
Bai J, Nakamura H, Hattori I, Tanito M, and Yodoi J (2002) Thioredoxin suppresses 1-methyl-4-phenylpyridinium-induced neurotoxicity in rat PC12 cells. Neurosci Lett 321:81-84.
-
(2002)
Neurosci Lett
, vol.321
, pp. 81-84
-
-
Bai, J.1
Nakamura, H.2
Hattori, I.3
Tanito, M.4
Yodoi, J.5
-
8
-
-
0001496694
-
A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine
-
Burns RS, Chiueh CC, Markey SP, Ebert MH, Jacobowitz DM, and Kopin IJ (1983) A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine. Proc Natl Acad Sci USA 80:4546-4550.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 4546-4550
-
-
Burns, R.S.1
Chiueh, C.C.2
Markey, S.P.3
Ebert, M.H.4
Jacobowitz, D.M.5
Kopin, I.J.6
-
9
-
-
0026074120
-
(-)Deprenyl induces activities of both superoxide dismutase and catalase but not of glutathione peroxidase in the striatum of young male rats
-
Carrillo MC, Kanai S, Nokubo M, and Kitani K (1991) (-)Deprenyl induces activities of both superoxide dismutase and catalase but not of glutathione peroxidase in the striatum of young male rats. Life Sci 48:517-521.
-
(1991)
Life Sci
, vol.48
, pp. 517-521
-
-
Carrillo, M.C.1
Kanai, S.2
Nokubo, M.3
Kitani, K.4
-
10
-
-
0023630084
-
Dopamine in the extrapyramidal motor function. a study based upon the MPTP-induced primate model of parkinsonism
-
Chiueh CC (1988) Dopamine in the extrapyramidal motor function. A study based upon the MPTP-induced primate model of parkinsonism. Ann NY Acad Sci 515:226-238.
-
(1988)
Ann NY Acad Sci
, vol.515
, pp. 226-238
-
-
Chiueh, C.C.1
-
11
-
-
85069009154
-
Cyclic GMP-mediated preconditioning gene induction as a treatment of Alzheimer's dementia and Parkinson's disease
-
(Mizuno Y, Fisher A, and Hanin I eds), Advances in Behavioral Biology, Kluwer Academic/Plenum Publishers, New York
-
Chiueh CC and Andoh T (2002) Cyclic GMP-mediated preconditioning gene induction as a treatment of Alzheimer's dementia and Parkinson's disease, in Mapping the Progress of Alzheimer's and Parkinson's Disease (Mizuno Y, Fisher A, and Hanin I eds), pp 447-454. Advances in Behavioral Biology, Vol. 51. Kluwer Academic/Plenum Publishers, New York.
-
(2002)
Mapping the Progress of Alzheimer's and Parkinson's Disease
, vol.51
, pp. 447-454
-
-
Chiueh, C.C.1
Andoh, T.2
-
12
-
-
0028658438
-
In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia
-
Chiueh CC, Wu RM, Mohanakumar KP, Sternberger LM, Krishna G, Obata T, and Murphy DL (1994) In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia. Ann NY Acad Sci 738:25-36.
-
(1994)
Ann NY Acad Sci
, vol.738
, pp. 25-36
-
-
Chiueh, C.C.1
Wu, R.M.2
Mohanakumar, K.P.3
Sternberger, L.M.4
Krishna, G.5
Obata, T.6
Murphy, D.L.7
-
13
-
-
0021712735
-
Pargyline and deprenyl prevent the neurotoxicity of 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP) in monkeys
-
Cohen G, Pasik P, Cohen B, Leist A, Mytilineou C, and Yahr MD (1984) Pargyline and deprenyl prevent the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) in monkeys. Eur J Pharmacol 106:209-210.
-
(1984)
Eur J Pharmacol
, vol.106
, pp. 209-210
-
-
Cohen, G.1
Pasik, P.2
Cohen, B.3
Leist, A.4
Mytilineou, C.5
Yahr, M.D.6
-
14
-
-
0028786336
-
Transcriptional regulation by MAP kinases
-
Davis RJ (1995) Transcriptional regulation by MAP kinases. Mol Reprod Dev 42:459-467.
-
(1995)
Mol Reprod Dev
, vol.42
, pp. 459-467
-
-
Davis, R.J.1
-
16
-
-
0036327342
-
Pergolide protects doperminergic neurons in primary culture under stress condition
-
Gille G, Rausch WD, Hung ST, Moldzio R, Janetzky B, Hundemer HP, Kolter T, and Reichman H (2002) Pergolide protects doperminergic neurons in primary culture under stress condition. J Neural Transm 109:633-643.
-
(2002)
J Neural Transm
, vol.109
, pp. 633-643
-
-
Gille, G.1
Rausch, W.D.2
Hung, S.T.3
Moldzio, R.4
Janetzky, B.5
Hundemer, H.P.6
Kolter, T.7
Reichman, H.8
-
17
-
-
0021224694
-
Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1, 2,5,6-tetrahydropyridine by monoamine oxidase inhibitors
-
Heikkila RE, Manzino L, Cabbat FS, Duvoisin RC, Heinonen EH, and Lammintausta R (1991) Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors. Nature (Lond) 311:467-469.
-
(1991)
Nature (Lond)
, vol.311
, pp. 467-469
-
-
Heikkila, R.E.1
Manzino, L.2
Cabbat, F.S.3
Duvoisin, R.C.4
Heinonen, E.H.5
Lammintausta, R.6
-
19
-
-
0141746553
-
Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha
-
Kang SW, Chae HZ, Seo MS, Kim K, Baines IC, and Rhee SG (1998) Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha. J Biol Chem 273:6297-6302.
-
(1998)
J Biol Chem
, vol.273
, pp. 6297-6302
-
-
Kang, S.W.1
Chae, H.Z.2
Seo, M.S.3
Kim, K.4
Baines, I.C.5
Rhee, S.G.6
-
20
-
-
0028260335
-
(-)Deprenyl increases the life span as well as activities of superoxide dismutase and catalase but not of glutathione peroxidase in selective brain regions in Fischer rats
-
Kitani K, Kanai S, Carrillo MC, and Ivy GO (1994) (-)Deprenyl increases the life span as well as activities of superoxide dismutase and catalase but not of glutathione peroxidase in selective brain regions in Fischer rats. Ann NY Acad Sci 717:60-71.
-
(1994)
Ann NY Acad Sci
, vol.717
, pp. 60-71
-
-
Kitani, K.1
Kanai, S.2
Carrillo, M.C.3
Ivy, G.O.4
-
21
-
-
0033770513
-
(-)Deprenyl (Selegiline): Past, present and future
-
Knoll J (2000) (-)Deprenyl (Selegiline): past, present and future. Neurobiology 8:179-199.
-
(2000)
Neurobiology
, vol.8
, pp. 179-199
-
-
Knoll, J.1
-
22
-
-
0032953601
-
Elevation of antioxidant potency in the brain of mice by low-dose γ-ray irradiation and its effect on 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced brain damage
-
Kojima S, Matsuki O, Nomura T, Yamaoka K, Takahashi M, and Niki E (1999) Elevation of antioxidant potency in the brain of mice by low-dose γ-ray irradiation and its effect on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced brain damage. Free Radic Biol Med 26:388-395.
-
(1999)
Free Radic Biol Med
, vol.26
, pp. 388-395
-
-
Kojima, S.1
Matsuki, O.2
Nomura, T.3
Yamaoka, K.4
Takahashi, M.5
Niki, E.6
-
23
-
-
0034721690
-
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
-
Kordower JH, Emborg ME, Bloch J, Ma SY, Chu Y, Leventhal L, McBride J, Chen EY, Palfi S, Roitberg BZ, et al. (2000) Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science (Wash DC) 290:767-773.
-
(2000)
Science (Wash DC)
, vol.290
, pp. 767-773
-
-
Kordower, J.H.1
Emborg, M.E.2
Bloch, J.3
Ma, S.Y.4
Chu, Y.5
Leventhal, L.6
McBride, J.7
Chen, E.Y.8
Palfi, S.9
Roitberg, B.Z.10
-
24
-
-
0037145696
-
Effects of shortand long-term (-)-deprenyl administration on mRNA for copper, zinc- And manganese-superoxide dismutase and glutathione peroxidase in rat brain
-
Kunikowska G, Gallagher I, Glover V, Clow A, and Jenner P (2002) Effects of shortand long-term (-)-deprenyl administration on mRNA for copper, zinc- and manganese-superoxide dismutase and glutathione peroxidase in rat brain. Brain Res 953:1-11.
-
(2002)
Brain Res
, vol.953
, pp. 1-11
-
-
Kunikowska, G.1
Gallagher, I.2
Glover, V.3
Clow, A.4
Jenner, P.5
-
25
-
-
0026308237
-
Deprenyl's effect at slowing progression of parkinsonian disability: The DATATOP study
-
The Parkinson Study Group
-
LeWitt PA (1991) Deprenyl's effect at slowing progression of parkinsonian disability: the DATATOP study. The Parkinson Study Group. Acta Neurol Scand Suppl 136:79-86.
-
(1991)
Acta Neurol Scand Suppl
, vol.136
, pp. 79-86
-
-
LeWitt, P.A.1
-
27
-
-
0020695378
-
Clinical and laboratory studies with selective monoamineoxidase- inhibiting drugs. Implications for hypothesized neurotransmitter changes associated with depression and antidepressant drug effects
-
Murphy DL, Cohen RM, Siever LJ, Roy B, Karoum F, Wyatt RJ, Garrick NA, and Linnoila M (1983) Clinical and laboratory studies with selective monoamineoxidase-inhibiting drugs. Implications for hypothesized neurotransmitter changes associated with depression and antidepressant drug effects. Mod Probl Pharmacopsychiatry 19:287-303.
-
(1983)
Mod Probl Pharmacopsychiatry
, vol.19
, pp. 287-303
-
-
Murphy, D.L.1
Cohen, R.M.2
Siever, L.J.3
Roy, B.4
Karoum, F.5
Wyatt, R.J.6
Garrick, N.A.7
Linnoila, M.8
-
28
-
-
0022394212
-
Deprenyl protects dopamine neurons from the neurotoxic effect of 1-methyl-4-phenylpyridinium ion
-
Mytilineou C and Cohen G (1985) Deprenyl protects dopamine neurons from the neurotoxic effect of 1-methyl-4-phenylpyridinium ion. J Neurochem 45:1951-1953.
-
(1985)
J Neurochem
, vol.45
, pp. 1951-1953
-
-
Mytilineou, C.1
Cohen, G.2
-
29
-
-
0031889724
-
Neuroprotection by S-nitrosoglutathione of brain dopamine neurons from oxidative stress
-
Rauhala P, Lin AM, and Chiueh CC (1998) Neuroprotection by S-nitrosoglutathione of brain dopamine neurons from oxidative stress. FASEB J 12:165-173.
-
(1998)
FASEB J
, vol.12
, pp. 165-173
-
-
Rauhala, P.1
Lin, A.M.2
Chiueh, C.C.3
-
30
-
-
0031260363
-
Deprenyl induces GFAP immunoreactivity in the intact and injured dopaminergic nigrostriatal system but fails to counteract axotomy- Induced degenerative changes
-
Revuelta M, Venero JL, Machado A, and Cano J (1997) Deprenyl induces GFAP immunoreactivity in the intact and injured dopaminergic nigrostriatal system but fails to counteract axotomy- induced degenerative changes. Glia 21:204-216.
-
(1997)
Glia
, vol.21
, pp. 204-216
-
-
Revuelta, M.1
Venero, J.L.2
Machado, A.3
Cano, J.4
-
31
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, and Ichijo H (1998) Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO (Eur Mol Biol Organ) J 17:2596-2606.
-
(1998)
EMBO (Eur Mol Biol Organ) J
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
32
-
-
0030574241
-
Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage
-
Semkova I, Wolz P, Schilling M, and Krieglstein J (1996) Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage. Eur J Pharmacol 315:19-30.
-
(1996)
Eur J Pharmacol
, vol.315
, pp. 19-30
-
-
Semkova, I.1
Wolz, P.2
Schilling, M.3
Krieglstein, J.4
-
33
-
-
0036231440
-
Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: A randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial
-
Shoulson I, Oakes D, Fahn S, Lang A, Langston JW, LeWitt P, Olanow CW, Penney JB, Tanner C, Kieburtz K, et al. (2002) Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial. Ann Neurol 51:604-612.
-
(2002)
Ann Neurol
, vol.51
, pp. 604-612
-
-
Shoulson, I.1
Oakes, D.2
Fahn, S.3
Lang, A.4
Langston, J.W.5
LeWitt, P.6
Olanow, C.W.7
Penney, J.B.8
Tanner, C.9
Kieburtz, K.10
-
34
-
-
0029078456
-
The monoamine oxidase-B inhibitor l-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits
-
Sprague JE and Nichols DE (1995) The monoamine oxidase-B inhibitor l-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits. J Pharmacol Exp Ther 273:667-673.
-
(1995)
J Pharmacol Exp Ther
, vol.273
, pp. 667-673
-
-
Sprague, J.E.1
Nichols, D.E.2
-
35
-
-
0023109435
-
Cognitive effects of l-deprenyl in Alzheimer's disease
-
Tariot PN, Sunderland T, Weingartner H, Murphy DL, Welkowitz JA, Thompson K, and Cohen RM (1987) Cognitive effects of l-deprenyl in Alzheimer's disease. Psychopharmacology 91:489-495.
-
(1987)
Psychopharmacology
, vol.91
, pp. 489-495
-
-
Tariot, P.N.1
Sunderland, T.2
Weingartner, H.3
Murphy, D.L.4
Welkowitz, J.A.5
Thompson, K.6
Cohen, R.M.7
-
36
-
-
0037734329
-
Neuroprotection by deprenyl and other propargylamines: Glyceraldehydes-3-phosphate dehydrogenase rather than monoamine oxidase B
-
Tatton WG, Chalmers-Redman RM, and Tatton NA (2003) Neuroprotection by deprenyl and other propargylamines: glyceraldehydes-3-phosphate dehydrogenase rather than monoamine oxidase B. J Neural Transm 110:509-515.
-
(2003)
J Neural Transm
, vol.110
, pp. 509-515
-
-
Tatton, W.G.1
Chalmers-Redman, R.M.2
Tatton, N.A.3
-
37
-
-
0030300164
-
(-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase
-
Tatton WG, Wadia JS, Ju WY, Chalmers-Redman RM, and Tatton NA (1996) (-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase. J Neural Transm Suppl 48:45-59.
-
(1996)
J Neural Transm Suppl
, vol.48
, pp. 45-59
-
-
Tatton, W.G.1
Wadia, J.S.2
Ju, W.Y.3
Chalmers-Redman, R.M.4
Tatton, N.A.5
-
38
-
-
0027173524
-
Protective effect of deprenyl against 1-methyl-4-phenylpyridinium neurotoxicity in rat striatum
-
Vizuete ML, Steffen V, Ayala A, Cano J, and Machado A (1993) Protective effect of deprenyl against 1-methyl-4-phenylpyridinium neurotoxicity in rat striatum. Neurosci Lett 152:113-116.
-
(1993)
Neurosci Lett
, vol.152
, pp. 113-116
-
-
Vizuete, M.L.1
Steffen, V.2
Ayala, A.3
Cano, J.4
Machado, A.5
-
40
-
-
0032531886
-
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2
-
Yang L, Matthews RT, Schulz JB, Klockgether T, Liao AW, Martinou JC, Penney JB Jr, Hyman BT, and Beal MF (1998) 1-Methyl-4-phenyl-1,2,3,6- tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2. J Neurosci 18:8145-8152.
-
(1998)
J Neurosci
, vol.18
, pp. 8145-8152
-
-
Yang, L.1
Matthews, R.T.2
Schulz, J.B.3
Klockgether, T.4
Liao, A.W.5
Martinou, J.C.6
Penney Jr., J.B.7
Hyman, B.T.8
Beal, M.F.9
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