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Volumn 19, Issue 1, 2008, Pages 30-40

LARG and mDia1 link Gα12/13 to cell polarity and microtubule dynamics

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PERICENTRIN; PROTEIN GA 12; PROTEIN GA 13; PROTEIN LARG; UNCLASSIFIED DRUG;

EID: 38749118958     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E06-11-1045     Document Type: Article
Times cited : (47)

References (62)
  • 1
    • 12344320203 scopus 로고    scopus 로고
    • Microtubule plus-end-tracking proteins: Mechanisms and functions
    • Akhmanova, A., and Hoogenraad, C. C. (2005). Microtubule plus-end-tracking proteins: mechanisms and functions. Curr. Opin. Cell Biol. 17, 47-54.
    • (2005) Curr. Opin. Cell Biol , vol.17 , pp. 47-54
    • Akhmanova, A.1    Hoogenraad, C.C.2
  • 3
    • 0031443277 scopus 로고    scopus 로고
    • The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation
    • Barrett, K., Leptin, M., and Settleman, J. (1997). The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation. Cell 91, 905-915.
    • (1997) Cell , vol.91 , pp. 905-915
    • Barrett, K.1    Leptin, M.2    Settleman, J.3
  • 4
    • 34247615185 scopus 로고    scopus 로고
    • GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases
    • Birkenfeld, J., Nalbant, P., Bohl, B. P., Pertz, O., Hahn, K. M., and Bokoch, G. M. (2007). GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases. Dev. Cell 12, 699-712.
    • (2007) Dev. Cell , vol.12 , pp. 699-712
    • Birkenfeld, J.1    Nalbant, P.2    Bohl, B.P.3    Pertz, O.4    Hahn, K.M.5    Bokoch, G.M.6
  • 5
    • 0036261720 scopus 로고    scopus 로고
    • Booden, M. A., Siderovski, D. P., and Der, C. J. (2002). Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA. Mol. Cell Biol. 22, 4053-4061.
    • Booden, M. A., Siderovski, D. P., and Der, C. J. (2002). Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA. Mol. Cell Biol. 22, 4053-4061.
  • 6
    • 35748946040 scopus 로고    scopus 로고
    • Get to grips: Steering local actin dynamics with IQGAPs
    • Brandt, D. T., and Grosse, R. (2007). Get to grips: steering local actin dynamics with IQGAPs. EMBO Rep. 8, 1019-1023.
    • (2007) EMBO Rep , vol.8 , pp. 1019-1023
    • Brandt, D.T.1    Grosse, R.2
  • 8
    • 9644278070 scopus 로고    scopus 로고
    • Homo-oligomerization is essential for F-actin assembly by the formin family FH2 domain
    • Copeland, J. W., Copeland, S. J., and Treisman, R. (2004). Homo-oligomerization is essential for F-actin assembly by the formin family FH2 domain. J. Biol. Chem. 279, 50250-50256.
    • (2004) J. Biol. Chem , vol.279 , pp. 50250-50256
    • Copeland, J.W.1    Copeland, S.J.2    Treisman, R.3
  • 9
    • 0036854328 scopus 로고    scopus 로고
    • The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization
    • Copeland, J. W., and Treisman, R. (2002). The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization. Mol. Biol. Cell 13, 4088-4099.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 4088-4099
    • Copeland, J.W.1    Treisman, R.2
  • 10
    • 26244449496 scopus 로고    scopus 로고
    • Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells
    • Czuchra, A., Wu, X., Meyer, H., van Hengel, J., Schroeder, T., Geffers, R., Rottner, K., and Brakebusch, C. (2005). Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells. Mol. Biol. Cell 16, 4473-4484.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4473-4484
    • Czuchra, A.1    Wu, X.2    Meyer, H.3    van Hengel, J.4    Schroeder, T.5    Geffers, R.6    Rottner, K.7    Brakebusch, C.8
  • 12
    • 0028218025 scopus 로고
    • Pericentrin, a highly conserved centrosome protein involved in microtubule organization
    • Doxsey, S. J., Stein, P., Evans, L., Calarco, P. D., and Kirschner, M. (1994). Pericentrin, a highly conserved centrosome protein involved in microtubule organization. Cell 76, 639-650.
    • (1994) Cell , vol.76 , pp. 639-650
    • Doxsey, S.J.1    Stein, P.2    Evans, L.3    Calarco, P.D.4    Kirschner, M.5
  • 13
    • 33845459805 scopus 로고    scopus 로고
    • The Formin mDia regulates GSK3{beta} through novel PKCs to promote microtubule stabilization but not MTOC reorientation in migrating fibroblasts
    • Eng, C. H., Huckaba, T. M., and Gundersen, G. G. (2006). The Formin mDia regulates GSK3{beta} through novel PKCs to promote microtubule stabilization but not MTOC reorientation in migrating fibroblasts. Mol. Biol. Cell 17, 5004-5016.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 5004-5016
    • Eng, C.H.1    Huckaba, T.M.2    Gundersen, G.G.3
  • 14
    • 0037434790 scopus 로고    scopus 로고
    • Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
    • Etienne-Manneville, S., and Hall, A. (2003). Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. Nature 421, 753-756.
    • (2003) Nature , vol.421 , pp. 753-756
    • Etienne-Manneville, S.1    Hall, A.2
  • 15
    • 33646864565 scopus 로고    scopus 로고
    • Staying in shape with formins
    • Faix, J., and Grosse, R. (2006). Staying in shape with formins. Dev. Cell 10, 693-706.
    • (2006) Dev. Cell , vol.10 , pp. 693-706
    • Faix, J.1    Grosse, R.2
  • 16
    • 0141533034 scopus 로고    scopus 로고
    • Roles of Rho-family GTPases in cell polarisation and directional migration
    • Fukata, M., Nakagawa, M., and Kaibuchi, K. (2003). Roles of Rho-family GTPases in cell polarisation and directional migration. Curr. Opin. Cell Biol. 15, 590-597.
    • (2003) Curr. Opin. Cell Biol , vol.15 , pp. 590-597
    • Fukata, M.1    Nakagawa, M.2    Kaibuchi, K.3
  • 18
    • 0034711449 scopus 로고    scopus 로고
    • Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho
    • Fukuhara, S., Chikumi, H., and Gutkind, J. S. (2000). Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho. FEBS Lett. 485, 183-188.
    • (2000) FEBS Lett , vol.485 , pp. 183-188
    • Fukuhara, S.1    Chikumi, H.2    Gutkind, J.S.3
  • 19
    • 0037223675 scopus 로고    scopus 로고
    • A plus-end raft to control microtubule dynamics and function
    • Galjart, N., and Perez, F. (2003). A plus-end raft to control microtubule dynamics and function. Curr. Opin. Cell Biol. 15, 48-53.
    • (2003) Curr. Opin. Cell Biol , vol.15 , pp. 48-53
    • Galjart, N.1    Perez, F.2
  • 21
    • 29644433350 scopus 로고    scopus 로고
    • Galpha12/13 is essential for directed cell migration and localized Rho-Dia1 function
    • Goulimari, P., Kitzing, T. M., Knieling, H., Brandt, D. T., Offermanns, S., and Grosse, R. (2005). Galpha12/13 is essential for directed cell migration and localized Rho-Dia1 function. J. Biol. Chem. 280, 42242-42251.
    • (2005) J. Biol. Chem , vol.280 , pp. 42242-42251
    • Goulimari, P.1    Kitzing, T.M.2    Knieling, H.3    Brandt, D.T.4    Offermanns, S.5    Grosse, R.6
  • 22
    • 0038240513 scopus 로고    scopus 로고
    • A role for VASP in RhoA-Diaphanous signalling to actin dynamics and SRF activity
    • Grosse, R., Copeland, J. W., Newsome, T. P., Way, M., and Treisman, R. (2003). A role for VASP in RhoA-Diaphanous signalling to actin dynamics and SRF activity. EMBO J. 22, 3050-3061.
    • (2003) EMBO J , vol.22 , pp. 3050-3061
    • Grosse, R.1    Copeland, J.W.2    Newsome, T.P.3    Way, M.4    Treisman, R.5
  • 23
    • 0034697039 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase mediates Ras activation by gonadotropin-releasing hormone
    • Grosse, R., Roelle, S., Herrlich, A., Hohn, J., and Gudermann, T. (2000). Epidermal growth factor receptor tyrosine kinase mediates Ras activation by gonadotropin-releasing hormone. J. Biol. Chem. 275, 12251-12260.
    • (2000) J. Biol. Chem , vol.275 , pp. 12251-12260
    • Grosse, R.1    Roelle, S.2    Herrlich, A.3    Hohn, J.4    Gudermann, T.5
  • 24
    • 0034110277 scopus 로고    scopus 로고
    • Contribution of receptor/G protein signaling to cell growth and transformation
    • Gudermann, T., Grosse, R., and Schultz, G. (2000). Contribution of receptor/G protein signaling to cell growth and transformation. Naunyn Schmiedebergs Arch. Pharmacol. 361, 345-362.
    • (2000) Naunyn Schmiedebergs Arch. Pharmacol , vol.361 , pp. 345-362
    • Gudermann, T.1    Grosse, R.2    Schultz, G.3
  • 25
    • 0035966322 scopus 로고    scopus 로고
    • Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1
    • Habas, R., Kato, Y., and He, X. (2001). Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell 107, 843-854.
    • (2001) Cell , vol.107 , pp. 843-854
    • Habas, R.1    Kato, Y.2    He, X.3
  • 26
    • 0033911382 scopus 로고    scopus 로고
    • Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during Drosophila morphogenesis
    • Halsell, S. R., Chu, B. I., and Kiehart, D. P. (2000). Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during Drosophila morphogenesis. Genetics 155, 1253-1265.
    • (2000) Genetics , vol.155 , pp. 1253-1265
    • Halsell, S.R.1    Chu, B.I.2    Kiehart, D.P.3
  • 27
    • 33744459471 scopus 로고    scopus 로고
    • Kelly, P., Moeller, B. J., Juneja, J., Booden, M. A., Der, C. J., Daaka, Y., Dewhirst, M. W., Fields, T. A., and Casey, P. J. (2006a). The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis. Proc. Natl. Acad. Sci. USA 103, 8173-8178.
    • Kelly, P., Moeller, B. J., Juneja, J., Booden, M. A., Der, C. J., Daaka, Y., Dewhirst, M. W., Fields, T. A., and Casey, P. J. (2006a). The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis. Proc. Natl. Acad. Sci. USA 103, 8173-8178.
  • 28
    • 33748744077 scopus 로고    scopus 로고
    • A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion
    • Kelly, P., Stemmle, L. N., Madden, J. F., Fields, T. A., Daaka, Y., and Casey, P. J. (2006b). A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion. J. Biol. Chem. 281, 26483-26490.
    • (2006) J. Biol. Chem , vol.281 , pp. 26483-26490
    • Kelly, P.1    Stemmle, L.N.2    Madden, J.F.3    Fields, T.A.4    Daaka, Y.5    Casey, P.J.6
  • 29
    • 0031042342 scopus 로고    scopus 로고
    • Relationship between the distribution of stress fibers and centrosomes in endothelial cells of the rat aorta
    • Kiosses, W. B., McKee, N. H., and Kalnins, V. I. (1997). Relationship between the distribution of stress fibers and centrosomes in endothelial cells of the rat aorta. Cell Motil. Cytoskeleton 36, 228-235.
    • (1997) Cell Motil. Cytoskeleton , vol.36 , pp. 228-235
    • Kiosses, W.B.1    McKee, N.H.2    Kalnins, V.I.3
  • 30
    • 33745737636 scopus 로고    scopus 로고
    • Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1
    • Kita, K., Wittmann, T., Nathke, I. S., and Waterman-Storer, C. M. (2006). Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1. Mol. Biol. Cell 17, 2331-2345.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 2331-2345
    • Kita, K.1    Wittmann, T.2    Nathke, I.S.3    Waterman-Storer, C.M.4
  • 32
    • 34247541603 scopus 로고    scopus 로고
    • Cortical microtubule contacts position the spindle in C. elegans embryos
    • Kozlowski, C., Srayko, M., and Nedelec, F. (2007). Cortical microtubule contacts position the spindle in C. elegans embryos. Cell 129, 499-510.
    • (2007) Cell , vol.129 , pp. 499-510
    • Kozlowski, C.1    Srayko, M.2    Nedelec, F.3
  • 33
    • 34250634798 scopus 로고    scopus 로고
    • Distinct regions of Galpha13 participate in its regulatory interactions with RGS homology domain-containing RhoGEFs
    • Kreutz, B., Hajicek, N., Yau, D. M., Nakamura, S., and Kozasa, T. (2007). Distinct regions of Galpha13 participate in its regulatory interactions with RGS homology domain-containing RhoGEFs. Cell Signal. 19, 1681-1689.
    • (2007) Cell Signal , vol.19 , pp. 1681-1689
    • Kreutz, B.1    Hajicek, N.2    Yau, D.M.3    Nakamura, S.4    Kozasa, T.5
  • 34
    • 0038709397 scopus 로고    scopus 로고
    • The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization
    • Ligon, L. A., Shelly, S. S., Tokito, M., and Holzbaur, E. L. (2003). The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization. Mol. Biol. Cell 14, 1405-1417.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 1405-1417
    • Ligon, L.A.1    Shelly, S.S.2    Tokito, M.3    Holzbaur, E.L.4
  • 35
    • 21344451993 scopus 로고    scopus 로고
    • Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements
    • Lin, F., Sepich, D. S., Chen, S., Topczewski, J., Yin, C., Solnica-Krezel, L., and Hamm, H. (2005). Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements. J. Cell Biol. 169, 777-787.
    • (2005) J. Cell Biol , vol.169 , pp. 777-787
    • Lin, F.1    Sepich, D.S.2    Chen, S.3    Topczewski, J.4    Yin, C.5    Solnica-Krezel, L.6    Hamm, H.7
  • 36
    • 33847776094 scopus 로고    scopus 로고
    • Microtubule-organizing centres: A re-evaluation
    • Luders, J., and Stearns, T. (2007). Microtubule-organizing centres: a re-evaluation. Nat. Rev. Mol. Cell Biol. 8, 161-167.
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 161-167
    • Luders, J.1    Stearns, T.2
  • 37
    • 0142026440 scopus 로고    scopus 로고
    • Search-and- capture of microtubules through plus-end-binding proteins (-TIPs)
    • Mimori-Kiyosue, Y., and Tsukita, S. (2003). "Search-and- capture" of microtubules through plus-end-binding proteins (-TIPs). J. Biochem. 134, 321-326.
    • (2003) J. Biochem , vol.134 , pp. 321-326
    • Mimori-Kiyosue, Y.1    Tsukita, S.2
  • 38
    • 33748637333 scopus 로고    scopus 로고
    • Integrin signalling in directed cell migration
    • Moissoglu, K., and Schwartz, M. A. (2006). Integrin signalling in directed cell migration. Biol. Cell 98, 547-555.
    • (2006) Biol. Cell , vol.98 , pp. 547-555
    • Moissoglu, K.1    Schwartz, M.A.2
  • 39
    • 0038234801 scopus 로고    scopus 로고
    • G-proteins as transducers in transmembrane signalling
    • Offermanns, S. (2003). G-proteins as transducers in transmembrane signalling. Prog. Biophys. Mol. Biol. 83, 101-130.
    • (2003) Prog. Biophys. Mol. Biol , vol.83 , pp. 101-130
    • Offermanns, S.1
  • 41
    • 0026068650 scopus 로고
    • The Drosophila gastrulation gene concertina encodes a G alpha-like protein
    • Parks, S., and Wieschaus, E. (1991). The Drosophila gastrulation gene concertina encodes a G alpha-like protein. Cell 64, 447-458.
    • (1991) Cell , vol.64 , pp. 447-458
    • Parks, S.1    Wieschaus, E.2
  • 43
    • 0035920247 scopus 로고    scopus 로고
    • Reuther, G. W., Lambert, Q. T., Booden, M. A., Wennerberg, K., Becknell, B., Marcucci, G., Sondek, J., Caligiuri, M. A., and Der, C. J. (2001). Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA. J. Biol. Chem. 276, 27145-27151.
    • Reuther, G. W., Lambert, Q. T., Booden, M. A., Wennerberg, K., Becknell, B., Marcucci, G., Sondek, J., Caligiuri, M. A., and Der, C. J. (2001). Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA. J. Biol. Chem. 276, 27145-27151.
  • 44
    • 0037009077 scopus 로고    scopus 로고
    • Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle
    • Rogers, S. L., Rogers, G. C., Sharp, D. J., and Vale, R. D. (2002). Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle. J. Cell Biol. 158, 873-884.
    • (2002) J. Cell Biol , vol.158 , pp. 873-884
    • Rogers, S.L.1    Rogers, G.C.2    Sharp, D.J.3    Vale, R.D.4
  • 45
    • 6944252346 scopus 로고    scopus 로고
    • Drosophila RhoGEF2 associates with microtubule plus ends in an EB1-dependent manner
    • Rogers, S. L., Wiedemann, U., Hacker, U., Turck, C., and Vale, R. D. (2004). Drosophila RhoGEF2 associates with microtubule plus ends in an EB1-dependent manner. Curr. Biol. 14, 1827-1833.
    • (2004) Curr. Biol , vol.14 , pp. 1827-1833
    • Rogers, S.L.1    Wiedemann, U.2    Hacker, U.3    Turck, C.4    Vale, R.D.5
  • 46
    • 34250902907 scopus 로고    scopus 로고
    • Rac inhibits thrombin-induced Rho activation: Evidence of a Pak-dependent GTPase crosstalk
    • Rosenfeldt, H., Castellone, M. D., Randazzo, P. A., and Gutkind, J. S. (2006). Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk. J. Mol. Signal. 1, 8.
    • (2006) J. Mol. Signal , vol.1 , pp. 8
    • Rosenfeldt, H.1    Castellone, M.D.2    Randazzo, P.A.3    Gutkind, J.S.4
  • 47
    • 0036305635 scopus 로고    scopus 로고
    • ROCK and Dia have opposing effects on adherens junctions downstream of Rho
    • Sahai, E., and Marshall, C. J. (2002). ROCK and Dia have opposing effects on adherens junctions downstream of Rho. Nat. Cell Biol. 4, 408-415.
    • (2002) Nat. Cell Biol , vol.4 , pp. 408-415
    • Sahai, E.1    Marshall, C.J.2
  • 48
    • 33845683023 scopus 로고    scopus 로고
    • The Schizosaccharomyces pombe EB1 homolog Mal3p binds and stabilizes the microtubule lattice seam
    • Sandblad, L., Busch, K. E., Tittmann, P., Gross, H., Brunner, D., and Hoenger, A. (2006). The Schizosaccharomyces pombe EB1 homolog Mal3p binds and stabilizes the microtubule lattice seam. Cell 127, 1415-1424.
    • (2006) Cell , vol.127 , pp. 1415-1424
    • Sandblad, L.1    Busch, K.E.2    Tittmann, P.3    Gross, H.4    Brunner, D.5    Hoenger, A.6
  • 50
    • 0030917227 scopus 로고    scopus 로고
    • The role of RhoA in tissue polarity and Frizzled signalling
    • Strutt, D. I., Weber, U., and Mlodzik, M. (1997). The role of RhoA in tissue polarity and Frizzled signalling. Nature 387, 292-295.
    • (1997) Nature , vol.387 , pp. 292-295
    • Strutt, D.I.1    Weber, U.2    Mlodzik, M.3
  • 52
    • 0037014472 scopus 로고    scopus 로고
    • Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology
    • Swiercz, J. M., Kuner, R., Behrens, J., and Offermanns, S. (2002). Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology. Neuron 35, 51-63.
    • (2002) Neuron , vol.35 , pp. 51-63
    • Swiercz, J.M.1    Kuner, R.2    Behrens, J.3    Offermanns, S.4
  • 53
    • 5644249233 scopus 로고    scopus 로고
    • Regulation of RGS-RhoGEFs by Galpha12 and Galpha13 proteins
    • Tanabe, S., Kreutz, B., Suzuki, N., and Kozasa, T. (2004). Regulation of RGS-RhoGEFs by Galpha12 and Galpha13 proteins. Methods Enzymol. 390, 285-294.
    • (2004) Methods Enzymol , vol.390 , pp. 285-294
    • Tanabe, S.1    Kreutz, B.2    Suzuki, N.3    Kozasa, T.4
  • 54
    • 0042206775 scopus 로고    scopus 로고
    • Receptor-dependent RhoA activation in G12/G13-deficient cells: Genetic evidence for an involvement of Gq/G11
    • Vogt, S., Grosse, R., Schultz, G., and Offermanns, S. (2003). Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11. J. Biol. Chem. 278, 28743-28749.
    • (2003) J. Biol. Chem , vol.278 , pp. 28743-28749
    • Vogt, S.1    Grosse, R.2    Schultz, G.3    Offermanns, S.4
  • 55
    • 0344758986 scopus 로고    scopus 로고
    • Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
    • Wang, H. R., Zhang, Y., Ozdamar, B., Ogunjimi, A. A., Alexandrova, E., Thomsen, G. H., and Wrana, J. L. (2003). Regulation of cell polarity and protrusion formation by targeting RhoA for degradation. Science 302, 1775-1779.
    • (2003) Science , vol.302 , pp. 1775-1779
    • Wang, H.R.1    Zhang, Y.2    Ozdamar, B.3    Ogunjimi, A.A.4    Alexandrova, E.5    Thomsen, G.H.6    Wrana, J.L.7
  • 56
    • 0030911424 scopus 로고    scopus 로고
    • p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin
    • Watanabe, N., Madaule, P., Reid, T., Ishizaki, T., Watanabe, G., Kakizuka, A., Saito, Y., Nakao, K., Jockusch, B. M., and Narumiya, S. (1997). p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. EMBO J. 16, 3044-3056.
    • (1997) EMBO J , vol.16 , pp. 3044-3056
    • Watanabe, N.1    Madaule, P.2    Reid, T.3    Ishizaki, T.4    Watanabe, G.5    Kakizuka, A.6    Saito, Y.7    Nakao, K.8    Jockusch, B.M.9    Narumiya, S.10
  • 58
    • 0029784842 scopus 로고    scopus 로고
    • Whitehead, I. P., Khosravi-Far, R., Kirk, H., Trigo-Gonzalez, G., Der, C. J., and Kay, R. (1996). Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors. J. Biol. Chem. 271, 18643-18650.
    • Whitehead, I. P., Khosravi-Far, R., Kirk, H., Trigo-Gonzalez, G., Der, C. J., and Kay, R. (1996). Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors. J. Biol. Chem. 271, 18643-18650.
  • 59
    • 0035178210 scopus 로고    scopus 로고
    • Cell motility: Can Rho GTPases and microtubules point the way?
    • Wittmann, T., and Waterman-Storer, C. M. (2001). Cell motility: can Rho GTPases and microtubules point the way? J. Cell Sci. 114, 3795-3803.
    • (2001) J. Cell Sci , vol.114 , pp. 3795-3803
    • Wittmann, T.1    Waterman-Storer, C.M.2
  • 60
    • 33748659504 scopus 로고    scopus 로고
    • The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src
    • Yamana, N. et al. (2006). The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src. Mol. Cell Biol. 26, 6844-6858.
    • (2006) Mol. Cell Biol , vol.26 , pp. 6844-6858
    • Yamana, N.1
  • 61
    • 33750493895 scopus 로고    scopus 로고
    • Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts
    • Yang, L., Wang, L., and Zheng, Y. (2006). Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts. Mol. Biol. Cell 17, 4675-4685.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 4675-4685
    • Yang, L.1    Wang, L.2    Zheng, Y.3
  • 62
    • 0032966501 scopus 로고    scopus 로고
    • Amorphous no longer: The centrosome comes into focus
    • Zimmerman, W., Sparks, C. A., and Doxsey, S. J. (1999). Amorphous no longer: the centrosome comes into focus. Curr. Opin. Cell Biol. 11, 122-128.
    • (1999) Curr. Opin. Cell Biol , vol.11 , pp. 122-128
    • Zimmerman, W.1    Sparks, C.A.2    Doxsey, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.