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Volumn 6, Issue 3, 2008, Pages 500-506

Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase

(13) Petković, Hrvoje a,e Sandmann, Axel b Challis, Iain R a Hecht, Hans Jürgen c Silakowski, Barbara c Low, Lindsey a Beeston, Nicola a Kuščer, Enej a,e Garcia Bernardo, Jose d Leadlay, Peter F a,d Kendrew, Steven G a Wilkinson, Barrie a Müller, Rolf b

a Biotica (United Kingdom)

b SAARLAND UNIVERSITY (Germany)

c HELMHOLTZ CENTRE FOR INFECTION RESEARCH (Germany)

d UNIVERSITY OF CAMBRIDGE (United Kingdom)

e UNIVERSITY OF LJUBLJANA (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; MOLECULAR STRUCTURE; MUTAGENESIS; SUBSTRATES;

ACYL TRANSFERASE; EPOTHILONE POLYKETIDE SYNTHASE; SUBSTRATE SELECTION;

ENZYME KINETICS;

HYBRID PROTEIN; LACTONE; POLYKETIDE SYNTHASE; TRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; SACCHAROPOLYSPORA; SITE DIRECTED MUTAGENESIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; HUMANS; LACTONES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POLYKETIDE SYNTHASES; PROTEIN HYBRIDIZATION; PROTEIN STRUCTURE, TERTIARY; SACCHAROPOLYSPORA; SUBSTRATE SPECIFICITY; TRANSFERASES;

EID: 38549152290 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/b714804f Document Type: Article

Times cited : (45)

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