Influence of virgin coconut oil on blood coagulation factors, lipid levels and LDL oxidation in cholesterol fed Sprague-Dawley rats

e-SPEN

Volumn 3, Issue 1, 2008, Pages

  Nevin, K G ^a   Rajamohan, T ^a  

^a UNIVERSITY OF KERALA   (India)

Author keywords

Atherosclerosis; Copra oil; PUFA; Risk factors; Sunflower oil; Thrombosis; Virgin coconut oil; Vitamins

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; ALPHA CAROTENE; ALPHA TOCOPHEROL; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 5; CHOLESTEROL; COCONUT OIL; COPPER ION; FIBRIN; FIBRINOGEN; GOLD WINNER; LOW DENSITY LIPOPROTEIN; PHYTOSTEROL; POLYPHENOL; PROTHROMBIN; RETINOL; SUNFLOWER OIL; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; VEGETABLE OIL; VIRGIN COCONUT OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; LIPID BLOOD LEVEL; LIPOPROTEIN METABOLISM; MALE; NONHUMAN; OXIDATION; PROTHROMBIN TIME; RAT; SPRAGUE DAWLEY RAT; THROMBOSIS; TRIACYLGLYCEROL BLOOD LEVEL; VITAMIN BLOOD LEVEL;

EID: 38549095649     PISSN: 17514991     EISSN: 17514991     Source Type: Journal    
DOI: 10.1016/j.eclnm.2007.09.003     Document Type: Article

References (65)

1. Kelleher C.C. Plasma fibrinogen and factor VII as risk factors for cardiovascular disease. Eur J Epidemiol 1 (1992) 79-82
2. Vinson J.A., Mandarano M.A., Shuta D.L., Bagchi M., and Bagchi D. Beneficial effects of a novel IH636 grape seed proanthocyanidin extract and a niacin-bound chromium in a hamster atherosclerosis model. Mol Cell Biochem 240 (2002) 99-103
3. Leadley R.J., Chi L., Rebello S.S., and Gagnon A. Contribution of in vivo models of thrombosis to the discovery and development of novel antithrombotic agents. J Pharmacol Toxicol Methods 43 (2000) 101-116
4. Wang X., and Xu L. An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research. Thromb Res 115 (2005) 95-100
5. Hoak J.C. Fatty acids in animals: thrombosis and hemostasis. Am J Clin Nutr 5 (1997) 1683S-1686S
6. Knapp H.R. Dietary fatty acids in human thrombosis and hemostasis. Am J Clin Nutr 65 (1997) 1687S-1698S
7. Nordoy A., and Goodnight S.H. Dietary lipids and thrombosis. Relationships to atherosclerosis. Arterioscler Thromb Vasc Biol 10 (1990) 149-163
8. Ferroni P., Basili S., and Davi G. New insights in the pathogenesis of prothrombotic state associated with hypercholesterolemia. Recenti Prog Med 95 (2004) 169-178
9. Expert Panel. Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel II). JAMA 269 (1993) 3015-3023
10. Glass C.K., and Witztum J.L. Atherosclerosis. The road ahead. Cell 104 (2001) 503-516
11. Niki E., and Noguchi N. Effects of antioxidants against atherosclerosis. Mol Cell Biochem 234 (2002) 19-25
12. Li L.X., Chen J.X., Liao D.F., and Yu L. Probucol inhibits oxidized-low density lipoprotein-induced adhesion of monocytes to endothelial cells by reducing P-selectin synthesis in vitro. Endothelium 6 (1998) 1-8
13. Thorin E., Hamilton C.A., Dominiczak M.H., and Reid J.L. Chronic exposure of cultured bovine endothelial cells to oxidized LDL abolishes prostacyclin release. Arterioscler Thromb 14 (1994) 453-459
14. Xu X.P., Meisel S.R., Ong J.M., Kaul S., Cercek B., Rajavashisth T.B., et al. Oxidized low-density lipoprotein regulates matrix metalloproteinase-9 and its tissue inhibitor in human monocyte-derived macrophages. Circulation 99 (1999) 993-998
15. Sini H., and Devi K.S. Antioxidant activities of the chloroform extract of Solanum trilobatum. Pharm Biol 42 (2004) 462-466
16. Kowada M., Ames A., Majno G., and Wright R.L. Cerebral ischemia: an improved experimental method for study cardiovascular effects and demonstration of an early vascular lesion in rabbit. J Neurosurg 28 (1968) 150-157
17. Ashton E.L., Best J.D., and Ball M.J. Effects of monounsaturated enriched sunflower oil on CHD risk factors including LDL size and copper-induced LDL oxidation. J Am Coll Nutr 20 (2001) 320-326
18. Nevin K.G., and Rajamohan T. Beneficial effects of virgin coconut oil on lipid parameters and in vitro LDL oxidation. Clin Biochem 37 (2004) 830-835
19. Butte W. Rapid method for the determination of fatty acid profiles from fats and oils using trimethylsulphonium hydroxide for transesterification. J Chromatogr 261 (1983) 142-145
20. Eder K., and Brandsch C. Effect of fatty acid composition of rapeseed oil on plasma lipids, fatty acid composition of tissues and susceptibility of low-density lipoprotein to lipid peroxidation in cholesterol-fed hamsters. Eur J Lipid Sci Technol 104 (2002) 3-13
21. Ramnik S. Clinical hematology, medical laboratory technology; methods and interpretations (1999), Med Pub (P) Ltd., India
22. Fearnley G.R., Chakrabarti R., and Evans J.E. Fibrinolytic treatment of rheumatoid arthritis with phenformin plus ethyloestrenol. Lancet 288 (1966) 757-761
23. King E.J., and Wootten I.D.P. Procedure for plasma. Microanalysis in medical biochemistry. 3rd ed. (1959), J&A Churchill (L), London
24. Daniel L.K. Enzymes in blood clotting. Methods Enzymol 2 (1955) 139-166
25. Powell W.S. Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica. Prostaglandins 20 (1980) 947-957
26. Wong P.Y., Malik K.U., Taylor B.M., Schneider W.P., McGiff J.C., and Sun F.F. Epoxidation of prostacyclin in the rabbit kidney. J Biol Chem 260 (1985) 9150-9153
27. Catiganin G.L. An HPLC method for the simultaneous determination of retinol and α-tocopherol in plasma or serum. Methods Enzymol 123 (1986) 215-219
28. Berlin E., Bhathena S.J., McClure D., and Peters R.C. Dietary menhaden and corn oils and the red blood cell membrane lipid composition and fluidity in hyper- and normocholesterolemic miniature swine. J Nutr 128 (1998) 1421-1428
29. Dodge J.T., Mitchell C., and Hanahan D.J. The preparation and chemical characteristics of hemoglobin free ghosts of human erythrocytes. Arch Biochem Biophys 100 (1963) 119-130
30. Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95 (1979) 351-358
31. Bairakatari E., Elisaf M., and Tzallas C. Evaluation of five methods for determining low density lipoprotein cholesterol (LDL-C) in hemodialysis patients. Clin Biochem 34 (2001) 593-602
32. Alder L., Hill J.S., and Frohlich J. Precipitation of apo B containing lipoproteins. Clin Biochem 33 (2000) 187-190
33. Abell L.L., Levy B.B., Brodie B.B., and Kendall F.E. A simplified method for the estimation of total cholesterol in serum and demonstration of its specificity. J Biol Chem 195 (1952) 357-366
34. Van Handel E., and Zilversmit D.B. Micromethod for the direct determination of serum triglycerides. J Lab Clin Med 50 (1957) 152-157
35. Brummel K.E., Butenas S., and Mann K.G. An integrated study of fibrinogen during blood coagulation. J Biol Chem 274 (1999) 22862-22870
36. Koopman J., Maas A., Rezaee F., Havekes L., Verheijen J., Gijbels M., et al. Fibrinogen and atherosclerosis: a study in transgenic mice. Fibrinolysis 11 (1997) 19-21
37. Katzmann J.A., Nesheim M.E., Hibbard L.S., and Mann K.G. Isolation of functional human coagulation factor V by using a hybridoma antibody. Proc Natl Acad Sci U S A 78 (1981) 162-166
38. Needleman P., Raz A., Minkes M.S., Ferrendelli J.A., and Sprecher H. Triene prostaglandins: prostacyclin and thromboxane biogenesis and unique biological properties. Proc Natl Acad Sci U S A 6 (1979) 944-948
39. Cylwik D., Mogielnicki A., Kramkowski K., Stokowski J., and Buczko W. Antithrombotic effect of L-arginine in hypertensive rats. J Physiol Pharmacol 55 (2004) 563-574
40. Stief T.W., Weippert M., Kretschmer V., and Renz H. Arginine inhibits hemostasis activation. Thromb Res 104 (2001) 265-274
41. Sarandol E., Safak O., Dirican M., and Uncu G. Oxidizability of apolipoprotein B-containing lipoproteins and serum paraoxonase/arylesterase activities in preeclampsia. Clin Biochem 37 (2004) 990-996
42. Buege J.A., and Aust S.D. Microsomal lipid peroxidation. Methods Enzymol 52 (1978) 302-310
43. Hu X., Jandacek R.J., and White W.S. Intestinal absorption of beta-carotene ingested with a meal rich in sunflower oil or beef tallow: postprandial appearance in triacylglycerol-rich lipoproteins in women. Am J Clin Nutr 71 (2000) 1170-1180
44. Hagve T.A., Lie O., and Gronn M. The effect of dietary N-3 fatty acids on osmotic fragility and membrane fluidity of human erythrocytes. Scand J Clin Lab Invest 215 (1993) 75-84
45. Palozza P., Sgarlata E., Luberto C., Piccioni E., Anti M., Marra G., et al. n-3 Fatty acids induce oxidative modifications in human erythrocytes depending on dose and duration of dietary supplementation. Am J Clin Nutr 64 (1996) 297-304
46. Laureles L.R., Rodriguez F.M., Reano C.E., Santos G.A., Laurena A.C., and Mendoza E.M. Variability in fatty acid and triacylglycerol composition of the oil of coconut (Cocos nucifera L.) hybrids and their parentals. J Agri Food Chem 50 (2002) 1581-1586
47. Blackburn G.L., Kater G., Mascioli E.A., Kowalchuck M., Babayan V.K., and Bistrian B.R. A re-evaluation of coconut oils effect on serum cholesterol and atherogenesis. J Philipp Med Assoc 65 (1989) 144-152
48. Lim-Sylianco C.Y., Mallorca R., Serrano E., and Wu L.S.A. A comparison of germ cell antigenotoxic activity of non dietary coconut oil and soyabean oil. Philipp J Coconut Stud 17 (1992) 1-5
49. Nestle P. Isoflavones: effects on cardiovascular risk and functions. International congress series. Atherosclerosis XIII.Proceedings of the 13th International atherosclerosis symposium 1262 (2004) 317-319
50. Leontowicz H., Gorinstein S., Lojek A., Leontowicz M.M., Soliva-Fortuny R., Park Y.-S., et al. Comparative content of some bioactive compounds in apples, peaches and pears and their influence on lipids and antioxidant capacity in rats. J Nutr Biochem 13 (2002) 603-610
51. Yamakoshi J., Kataoka S., Koga T., and Ariga T. Proanthocyanidin-rich extract from grape seeds attenuates the development of aortic atherosclerosis in cholesterol-fed rabbits. Atherosclerosis 142 (1999) 139-149
52. Constantinescu A., Han D., and Packer L. Vitamin E recycling in human erythrocyte membranes. J Biol Chem 268 (1993) 10906-10913
53. Steiner M. Vitamin E, a modifier of platelet function: rationale and use in cardiovascular and cerebrovascular disease. Nutr Rev 57 (1999) 306-309
54. Wu D., Koga T., Martin K.R., and Meydani M. Effect of vitamin E on human aortic endothelial cell production of chemokines and adhesion to monocytes. Atherosclerosis 147 (1999) 297-307
55. Gökkusu C., Özden T.A., and Mostafa T. The relationship between oxidative stress and membrane ATPase enzyme activities in hypercholesterolemic rats supplemented with vitamin. Eur J Med 4 (2004) 70-76
56. Jayakumari N., Ambikakumari V., Balakrishnan K.G., and Iyer K.S. Antioxidant status in relation to free radical production during stable and unstable anginal syndromes. Atherosclerosis 94 (1992) 183-190
57. Riemersma R.A., Wood D.A., Macintyre C.C., Elton R.A., Gey K.F., and Oliver M.F. Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene. Lancet 337 (1991) 1-5
58. Nilsson J. Lipoproteins and inflammation in atherosclerosis. Fibrinolysis 11 (1997) 129-132
59. Kawai Y., Saito A., Shibata N., Kobayashi M., Yamada S., Osawa T., et al. Covalent binding of oxidized cholesteryl esters to protein: implications for oxidative modification of low density lipoprotein and atherosclerosis. J Biol Chem 278 (2003) 21040-21049
60. Banfi C., Camera M., Giandomenico G., Toschi V., Arpaia M., Mussoni L., et al. Vascular thrombogenicity induced by progressive LDL oxidation: protection by antioxidants. Thromb Haemost 89 (2003) 544-553
61. Esterbauer H., Puhl H., Dieber-Rotheneder M., Waeg G., and Rabl H. Effect on oxidative modification of LDL. Ann Med 23 (1991) 573-581
62. Quinn M.T., Parthasarathy S., Fong L.G., and Steinberg D. Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis. Proc Natl Acad Sci U S A 84 (1987) 2995-2998
63. Ishii H., Kizaki K., Horie S., and Kazama M. Oxidized low density lipoprotein reduces thrombomodulin transcription in cultured human endothelial cells through degradation of the lipoprotein in lysosomes. J Biol Chem 271 (1996) 8458-8465
64. Grafe M., Auch-Schwelk W., Hertel H., Terbeek D., Steinheider G., Loebe M., et al. Human cardiac microvascular and macrovascular endothelial cells respond differently to oxidatively modified LDL. Atherosclerosis 137 (1998) 87-95
65. Allison B.A., Nilsson L., Karpe F., Hamsten A., and Eriksson P. Effects of native, triglyceride enriched, and oxidatively modified LDL on plasminogen activator inhibitor-1 expression in human endothelial cells. Arterioscler Thromb Vasc Biol 19 (1999) 1354-1360