Synthesis of an unusual branched-chain sugar, 5-C-methyl-L-idopyranose for SAR studies of pyranmycins: Implication for the future design of aminoglycoside antibiotics

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 17, 2004, Pages 4389-4393

  Wang, Jinhua ^a   Li, Jie ^a   Czyryca, Przemyslaw G ^a   Chang, Huiwen ^a   Kao, Jeff ^b   Tom Chang, Cheng Wei ^a  

^a UTAH STATE UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

Aminoglycoside antibiotics; Antibacterial; Branched chain sugar; Drug development; Pyranmycins

Indexed keywords

5 C METHYL LEVO IDOPYRANOSE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; PYRAN DERIVATIVE; SUGAR; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; HEXOSES; MICROBIAL SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 3843122215     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.06.064     Document Type: Article

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32. +]) m/e 499.2615; measure m/e 499.2605