Pyranmycins, a Novel Class of Aminoglycosides with Improved Acid Stability: The SAR of D-Pyranoses on Ring III of Pyranmycin

Organic Letters

Volumn 4, Issue 26, 2002, Pages 4603-4606

  Chang, Cheng Wei Tom ^a   Hui, Yu ^a   Elchert, Bryan ^a   Wang, Jinhua ^a   Li, Jie ^a   Rai, Ravi ^a  

^a UTAH STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; HYDROCHLORIC ACID; NEOMYCIN; PYRANMYCIN; PYRONE DERIVATIVE; TRISACCHARIDE;

ARTICLE; CARBOHYDRATE ANALYSIS; CHEMISTRY; CONFORMATION; DRUG STABILITY; MOLECULAR GENETICS; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; DRUG STABILITY; HYDROCHLORIC ACID; MOLECULAR SEQUENCE DATA; NEOMYCIN; PYRONES; STRUCTURE-ACTIVITY RELATIONSHIP; TRISACCHARIDES;

EID: 0141661741     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0269042     Document Type: Article

References (7)

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3. Cohen, M. L. Science 2002, 257, 1050-1055.
4. (b) Neu, H. C. Science 2002, 257, 1064-1072.
5. These glycosyl acetates were prepared from peracetylation of lactose, maltose, and xylose purchased from Acros Chemical Co.
6. 4).
7. Schmidt, R. R.; Jung K.-H. In Preparative Carbohydrate Chemistry; Hannessian, S., Ed.; Marcel Dekker: New York, 1997; p 297.