Generation of highly potent nonviral gene vectors by complexation of lipoplexes and transferrin-bearing fusogenic polymer-modified liposomes in aqueous glucose solution

Biomaterials

Volumn 29, Issue 9, 2008, Pages 1262-1272

  Sakaguchi, Naoki ^a   Kojima, Chie ^a   Harada, Atsushi ^a   Koiwai, Kazunori ^b   Shimizu, Kazuhiro ^b   Emi, Nobuhiko ^c   Kono, Kenji ^a  

^a Osaka Prefecture University   (Japan)

^b TERUMO CORPORATION   (Japan)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Fusion; Gene therapy; Lipoplex; Liposome; Nonviral vector; Transferrin

Indexed keywords

LIPOSOME COMPLEXES; NONVIRAL VECTORS; TRANSFECTION ACTIVITY;

ACIDITY; BIOACTIVITY; FUSION REACTIONS; GLUCOSE; LIPOSOMES; SOLUTIONS;

GENETIC ENGINEERING;

3,5 DIPENTADECYLOXYBENZAMIDINE; BENZAMIDINE DERIVATIVE; GLUCOSE; GLYCIDOL; LIPOPLEX; LIPOSOME; PHOSPHATE BUFFERED SALINE; POLYMER; SUCCINYLATED POLY(GLYCIDOL); TRANSFERRIN; TRX 20; UNCLASSIFIED DRUG;

ACIDITY; AQUEOUS SOLUTION; ARTICLE; BINDING AFFINITY; CELL SPECIFICITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; LIGAND BINDING; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; TARGET CELL;

BENZAMIDINES; BIOCOMPATIBLE MATERIALS; CHOLESTEROL; FATTY ACIDS; GENE THERAPY; GENETIC VECTORS; GLUCOSE; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; LIPOSOMES; MATERIALS TESTING; MEMBRANE FUSION; MICROSCOPY, ATOMIC FORCE; PARTICLE SIZE; POLYMERS; PROPYLENE GLYCOLS; SOLUTIONS; TRANSFECTION; TRANSFERRIN;

EID: 38349022507     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2007.11.016     Document Type: Article

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