Enhancement of transfection activity of lipoplexes by complexation with transferrin-bearing fusogenic polymer-modified liposomes

International Journal of Pharmaceutics

Volumn 325, Issue 1-2, 2006, Pages 186-190

  Sakaguchi, Naoki ^a   Kojima, Chie ^a   Harada, Atsushi ^a   Koiwai, Kazunori ^b   Shimizu, Kazuhiro ^b   Emi, Nobuhiko ^c   Kono, Kenji ^a  

^a Osaka Prefecture University   (Japan)

^b TERUMO CORPORATION   (Japan)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cationic liposome; Fusogenic liposome; Gene delivery; Lipoplex; Transferrin

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; 3' [N (N',N' DIMETHYLAMINOETHANE)CARBAMOYL]CHOLESTEROL; 3,5 DIPENTADECYLOXYBENZAMIDINE; BENZAMIDINE DERIVATIVE; CHOLESTEROL DERIVATIVE; GLYCIDOL; LIPOPLEX; LIPOSOME; TRANSFERRIN; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; DRUG DELIVERY SYSTEM; ENHANCER REGION; GENE DELIVERY SYSTEM; GENE THERAPY; GENETIC TRANSFECTION; PRIORITY JOURNAL;

GENETIC VECTORS; HELA CELLS; HUMANS; LIPOSOMES; LUCIFERASES; MODELS, GENETIC; POLYMERS; RECOMBINANT FUSION PROTEINS; TECHNOLOGY, PHARMACEUTICAL; TRANSFECTION; TRANSFERRIN;

EID: 33750024189     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.06.015     Document Type: Article

References (20)

1. Boussif O., Lezoualc'h F., Zanta M.A., Mergny M.D., Scherman D., Demeneix B., and Behr J.P. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 7297-7301
2. Brown M.D., Schätzlein A.G., and Uchegbu I.F. Gene delivery with synthetic (non-viral) carriers. Int. J. Pharm. 229 (2001) 1-21
3. Farhood H., Serbina N., and Huang L. The role of dioleoylphosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim. Biophys. Acta 1235 (1995) 289-295
4. Friend D.S., Papahadjopoulos D., and Debs R.J. Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. Biochim. Biophys. Acta 1278 (1996) 41-50
5. Harigai T., Kondo M., Isozaki M., Kasukawa H., Hagiwara H., Uchiyama H., and Kimura J. Preferential binding of polyethylene glycol-coated liposomes containing a novel cationic lipid, TRX-20, to human subendothelial cells via chondritin sulfate. Pharm. Res. 18 (2001) 1284-1290
6. Kamata H., Yagisawa H., Takahashi S., and Hirata H. Amphiphilic peptides enhance the efficiency of liposome-mediated DNA transfection. Nucleic Acids Res. 22 (1994) 536-537
7. Kichler A., Mechtler K., Behr J.P., and Wagner E. Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer. Bioconjugate Chem. 8 (1997) 213-221
8. Kono K., Zenitani K., and Takagishi T. Novel pH-sensitive liposomes: liposomes bearing a poly(ethylene glycol) derivatives. Biochim. Biophys. Acta 1193 (1994) 1-9
9. Kono K., Igawa T., and Takagishi T. Cytoplasmic delivery mediated by liposomes modified with a pH-sensitive poly(ethylene glycol) derivative. Biochim. Biophys. Acta 1325 (1997) 143-154
10. Kono K., Torikoshi Y., Mitsutomi M., Itoh T., Emi N., Yanagie H., and Takagishi T. Novel gene delivery systems: complexes of fusogenic polymer-modified liposomes and lipoplexes. Gene Ther. 8 (2001) 5-12
11. Mok K.W.C., and Cullis P.R. Structural and fusogenic properties of cationic liposomes in the presence of plasmid DNA. Biophys. J. 73 (1997) 2534-2545
12. Mönkkönen J., and Urtti A. Lipid fusion in oligonucleotide and gene delivery with cationic lipids. Adv Drug Delivery Rev. 34 (1998) 37-49
13. Niidome T., and Huang L. Gene therapy progress and prospects: non-viral vectors. Gene Ther. 9 (2002) 1647-1652
14. Pouton C.W., and Seymour L.W. Key issues in non-viral gene delivery. Adv. Drug Deliv. Rev. 34 (1998) 3-19
15. Simoes S., Slepushkin V., Gaspar R., de Lima M.C.P., and Düzgünes N. Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusogenic peptides. Gene Therapy 5 (1998) 955-964
16. Sonawane N.D., Szoka Jr. F.C., and Verkman A.S. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J. Biol. Chem. 278 (2003) 44826-44831
17. Takahashi T., Kono K., Itoh T., Emi N., and Takagishi T. Synthesis of novel cationic lipids having polyamidoamine dendrons and their transfection activity. Bioconjugate Chem. 14 (2003) 764-773
18. Takahashi T., Harada A., Emi N., and Kono K. Preparation of efficient gene carriers using a polyamidoamine dendron-bearing lipid: improvement of serum resistance. Bioconjugate Chem. 16 (2005) 1160-1165
19. Wagner E. Application of membrane-active peptides for non-viral gene delivery. Adv. Drug Deliv. Rev. 38 (1999) 279-289
20. Zabner J., Fasbender A.J., Moninger T., Poellinger K.A., and Welsh M.J. Cellular and molecular barriers to gene transfer by a cationic lipid. J. Biol. Chem. 270 (1995) 18997-19007