Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation

Molecular Therapy

Volumn 10, Issue 4, 2004, Pages 719-729

  Fumoto, Shintaro ^a   Kawakami, Shigeru ^a   Ito, Yoshitaka ^a   Shigeta, Kosuke ^a   Yamashita, Fumiyoshi ^a   Hashida, Mitsuru ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Cationic liposomes; Gene therapy; Hepatocytes; Plasmid DNA; Targeting

Indexed keywords

ASIALOGLYCOPROTEIN RECEPTOR; CATION; LIPOSOME; PLASMID DNA; RECEPTOR BLOCKING AGENT; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CELL SPECIFICITY; CELL STRAIN HEPG2; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA TRANSFECTION; DRUG DESIGN; DRUG DISTRIBUTION; DRUG RELEASE; DRUG STABILITY; FEMALE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER CELL; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; THEORY; TRANSGENE;

ANIMALS; CELL LINE; DNA; FEMALE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GALACTOSE; GENE EXPRESSION; HEPATOCYTES; LIPOSOMES; LIVER; LUCIFERASES; MALE; MICE; MICE, INBRED ICR; PERFUSION; PLASMIDS; RATS; RATS, WISTAR; SODIUM CHLORIDE; TRANSFECTION;

EID: 4644247385     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.07.015     Document Type: Article

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