Aluminum inhibits proteolytic degradation of amyloid β peptide by cathepsin D: A potential link between aluminum accumulation and neuritic plaque deposition

FEBS Letters

Volumn 580, Issue 28-29, 2006, Pages 6543-6549

  Sakamoto, Takashi ^a   Saito, Hisaka ^a   Ishii, Kazuyuki ^a   Takahashi, Hidenobu ^a   Tanabe, Shinzo ^a   Ogasawara, Yuki ^a  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Aluminum; Alzheimer's Disease; Amyloid peptide; Cathepsin D; Inhibition

Indexed keywords

ALUMINUM; AMYLOID BETA PROTEIN; CATHEPSIN D; DEFEROXAMINE;

ARTICLE; CATABOLISM; CONTROLLED STUDY; ENZYME SUBSTRATE; HUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; SENILE PLAQUE;

ALUMINUM; AMYLOID BETA-PROTEIN; CATHEPSIN D; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; DEFEROXAMINE; HEMOGLOBINS; HUMANS; IRON; PROTEIN DENATURATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, SECONDARY; SENILE PLAQUES; ZINC;

EID: 37849189833     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.10.075     Document Type: Article

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