Human brain carboxypeptidase B, which cleaves β-amyloid peptides in vitro, is expressed in the endoplasmic reticulum of neurons

European Journal of Neuroscience

Volumn 13, Issue 9, 2001, Pages 1653-1657

  Matsumoto, Akira ^a   Itoh, Kyoko ^a   Seki, Tsuneyoshi ^a   Motozaki, Kenjiro ^a   Matsuyama, Shogo ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

amyloid peptides; Alzheimer's disease; Endoplasmic reticulum; Exopeptidase; Human brain carboxypeptidase B; Secretase

Indexed keywords

AMYLOID BETA PROTEIN; CARBOXYPEPTIDASE B; EXOPEPTIDASE; HEAT SHOCK PROTEIN 70; PROTEINASE; SYNTHETIC PEPTIDE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CASE REPORT; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; DENSITY GRADIENT CENTRIFUGATION; DOSE RESPONSE; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MICROSOME; NERVE CELL; PERIKARYON; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PURIFICATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANTIBODY SPECIFICITY; CARBOXYPEPTIDASE B; CARBOXYPEPTIDASES; CARRIER PROTEINS; CENTRIFUGATION, DENSITY GRADIENT; ENDOPLASMIC RETICULUM; EPITOPE MAPPING; HEAT-SHOCK PROTEINS; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSOMES; MIDDLE AGED; MOLECULAR CHAPERONES; NEURONS; OLIGOPEPTIDES; PROTEIN STRUCTURE, TERTIARY; SUBCELLULAR FRACTIONS;

EID: 0035000638     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816x.2001.01540.x     Document Type: Article

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